Recombinant Mouse anti-Human GTF2B Monoclonal antibody (JJC2)

Name: Recombinant Mouse anti-Human GTF2B Monoclonal antibody (JJC2)
SKU: MOB-2012CT
Rating: 5 (1 reviews)

CAT#: MOB-2012CT

Recombinant Mouse monoclonal antibody to Human GTF2B, expressed in Chinese Hamster Ovary cells(CHO).

Gene Expression

Subcellular Location Figure 1 IF staining of human cell line HEK 293

Immunofluorescent staining of human cell line HEK 293 shows localization to nucleoplasm & nuclear bodies.

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/61626/1153_H2_2_selected.jpg

Normal Tissue Figure 2 IHC staining of human rectum

Immunohistochemical staining of human rectum shows strong nuclear positivity in glandular cells.

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/61626/ihc_selected.jpg

Normal Tissue Figure 3 Cerebral cortex

Neuronal cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Nuclear

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/61626/140313_B_9_5.jpg

Normal Tissue Figure 4 Colon

Endothelial cells Staining: Medium Intensity: Moderate Quantity:>75% Location: nuclear Glandular cells Staining: High Intensity: Strong Quantity:>75% Location: nuclear Peripheral nerve/ganglion Staining: Medium Intensity: Moderate Quantity:>75% Location: Nuclear

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/61626/140313_A_9_3.jpg

Normal Tissue Figure 5 Kidney

Cells in glomeruli Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous nuclear Cells in tubules Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous nuclear

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/61626/140313_A_8_5.jpg

Normal Tissue Figure 6 Testis

Leydig cells Staining: Medium Intensity: Moderate Quantity:>75% Pachytene spermatocytes Staining: High Intensity: Strong Quantity: 75%-25% Peritubular cells Staining: Medium Intensity: Moderate Quantity:>75% Preleptotene spermatocytes Staining: High Intensity: Strong Quantity:>75% Round or early spermatids Staining: Medium Intensity: Moderate Quantity:>75% Sertoli cells Staining: High Intensity: Strong Quantity:>75% Spermatogonia cells Staining: High Intensity: Strong

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/61626/140313_A_4_6.jpg

Normal Tissue Figure 7 Lymph node

Germinal center cells Staining: Medium Intensity: Moderate Quantity:>75% Location: nuclear Non-germinal center cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Nuclear

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/61626/140313_A_9_8.jpg

RNA Expression Figure 8 RNA cell line category: Low cell line specificity

Cell lines ordered by descending RNA expression order

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000137947-GTF2B

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Specifications

Immunogen
Human TFIIB eukaryotic transcription factor.

Host Species
Mouse

Species Reactivity
Human

Clone
JJC2

Applications
Used for immunoassay techniques such as: ChImmunoprecipitation; Immunoprecipitation; Western Blot

Conjugate
Unconjugated

Product Property

Purity
Ascites

Format
Liquid

Buffer
Preservative: None Constituents: Raw Ascites

Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

Target

Alternative Names
GTF2B; general transcription factor IIB; TF2B; TFIIB; transcription initiation factor IIB; S300-II; general transcription factor TFIIB; RNA polymerase II transcription factor IIB;

Gene ID
2959

UniProt ID
Q00403

Protein Refseq
NP_001505

Function
DNA binding; metal ion binding; protein binding; thyroid hormone receptor binding; transcription factor binding; translation initiation factor activity; zinc ion binding;

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Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Datasheet

Datasheet - MOB-2012CT.pdf

MSDS

MSDS - MOB-2012CT.pdf

COA

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