Anti-Human IFN alpha Recombinant Antibody (Rontalizumab) (CAT#: TAB-074)
Recombinant monoclonal antibody to IFN alpha. Rontalizumab is a humanized monoclonal antibody. for treatment of systemic lupus erythematosus.
Specific Inquiry
WB
Figure 1 The human antibody specifically recognized IFNα1b but not recombinant IFNα2b or IFNγ as determined by Western blotting.
Purified human IFNα1b, IFNα2b and IFNγ were probed with AIFNα1bIgG01.
Ouyang, S., Gong, B., Li, J. Z., Zhao, L. X., Wu, W., Zhang, F. S., ... & Liang, W. (2012). Structural insights into a human anti-IFN antibody exerting therapeutic potential for systemic lupus erythematosus. Journal of molecular medicine, 90(7), 837-846.
Specifications
- Immunogen
- The details of the immunogen for this antibody are not available.
- Host Species
- Mouse
- Derivation
- Humanized (from mouse)
- Type
- IgG1 - kappa
- Specificity
- Tested positive against native human antigen.
- Species Reactivity
- Human
- Applications
- WB
- CAS
- 948570-30-7
- Generic Name
- Rontalizumab
- UNII
- LDO2FIQ61I
- MW
- 145.9 kDa
- Related Disease
- Systemic lupus erythematosus (SLE)
Product Property
- Purity
- >95.0%, determined by analysis by RP-HPLC & analysis by SDS-PAGE.
- Storage
- Store it under sterile conditions at -20°C upon receiving. Recommend to pack the protein into smaller quantities for optimal storage.
Applications
- Application Notes
- The IFN alpha antibody has been reported in applications of Western Blot.
Target
- Alternative Names
- Rontalizumab;948570-30-7;rhuMAb IFN alpha;RG7415;IFNA1;interferon, alpha 1;interferon alpha-1/13;IFL;IFN;IFN ALPHA;IFN alpha 1b;IFN alphaD;IFNA13;IFNA@;interferon alpha 1b;leIF D;IFN-alpha 1b;IFN-alpha-1/13;interferon-alpha1;interferon alpha-D;IFN-ALPHA;I
- Gene ID
- 3439
- UniProt ID
- P01562
Related Resources
Please refer to Rontalizumab Overview to learn more about the mechanism of action, clinical projects, and approved drugs of Rontalizumab.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "Rontalizumab"
Afuco™ Anti-IFNA1 ADCC Recombinant Antibody (Rontalizumab), ADCC EnhancedThis product is an ADCC enhanced antibody produced by our Afuco™ platform. Recombinant monoclonal antibody to IFN alpha. Rontalizumab is a humanized monoclonal antibody. for treatment of systemic lupus erythematosus.
See other products for "IFNA1"
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1099z | Mouse Anti-IFNA1 Recombinant Antibody (clone 42B6) | ELISA, WB, FuncS | Mouse IgG1 |
| HPAB-0055LY | Human Anti-IFNA1 Recombinant Antibody (HPAB-0055LY) | ELISA, Inhib, FC | Humanized IgG4 |
| HPAB-0056LY | Mouse Anti-IFNA1 Recombinant Antibody (HPAB-0056LY) | FC, ELISA | Mouse IgG |
| MRO-1955-CN | Rabbit Anti-IFNA1 Polyclonal Antibody (MRO-1955-CN) | WB, IF, IHC, FC | Rabbit IgG |
| HPAB-0127-WJ | Human Anti-IFNA1 Recombinant Antibody (HPAB-0127-WJ) | ELISA, SPR, Neut, WB, Inhib | Human IgG, λ |
Mouse Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-747 | Anti-IFNA1 Recombinant Antibody (Faralimomab) | FuncS, IF, Neut, ELISA, FC, IP, IHC | IgG1 |
Human Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-H62 | Anti-Human IFNA1 Recombinant Antibody (Sifalimumab) | ELISA, Inhib | IgG1 - kappa |
Neutralizing Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-960CQ | Mouse Anti-IFNA1 Recombinant Antibody (clone N27) | WB, Neut, ELISA | Mouse IgG1, κ |
| NEUT-961CQ | Mouse Anti-IFNA1 Recombinant Antibody (clone 8U18) | Neut, WB | Mouse IgG1 |
| NEUT-1070CQ | Mouse Anti-IFNA1 Recombinant Antibody (clone F17) | Neut | Mouse IgG1 |
| NEUT-1071CQ | Mouse Anti-IFNA1 Recombinant Antibody (clone K9) | Neut | Mouse IgG1 |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-4599 | Rabbit Anti-IFNA1 Recombinant Antibody (clone TH112DS) | WB | Rabbit IgG |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0322-YC-S(P) | Mouse Anti-IFNA1 Recombinant Antibody; scFv Fragment (HPAB-0322-YC-S(P)) | Neut, ELISA | Mouse scFv |
| HPAB-0323-YC-S(P) | Human Anti-IFNA1 Recombinant Antibody; scFv Fragment (HPAB-0323-YC-S(P)) | ELISA | Humanized scFv |
| HPAB-0055LY-S(P) | Human Anti-IFNA1 Recombinant Antibody; scFv Fragment (HPAB-0055LY-S(P)) | ELISA, Inhib, FC | Humanized scfv |
| HPAB-0056LY-S(P) | Mouse Anti-IFNA1 Recombinant Antibody; scFv Fragment (HPAB-0056LY-S(P)) | ELISA, Inhib, FC | Mouse scfv |
| HPAB-0127-WJ-S(P) | Human Anti-IFNA1 Recombinant Antibody; scFv Fragment (HPAB-0127-WJ-S(P)) | ELISA | Human scFv |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0322-YC-F(E) | Mouse Anti-IFNA1 Recombinant Antibody; Fab Fragment (HPAB-0322-YC-F(E)) | Neut, ELISA | Mouse Fab |
| HPAB-0323-YC-F(E) | Human Anti-IFNA1 Recombinant Antibody; Fab Fragment (HPAB-0323-YC-F(E)) | ELISA | Humanized Fab |
| HPAB-0324-YC-F(E) | Human Anti-IFNA1 Recombinant Antibody; Fab Fragment (HPAB-0324-YC-F(E)) | ELISA | Human Fab |
| HPAB-0325-YC-F(E) | Human Anti-IFNA1 Recombinant Antibody (clone AIA22); Fab Fragment | ELISA, Neut | Human Fab |
| HPAB-0127-WJ-F(E) | Human Anti-IFNA1 Recombinant Antibody; Fab Fragment (HPAB-0127-WJ-F(E)) | ELISA | Human Fab |
ADCC Enhanced Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AFC-TAB-747 | Afuco™ Anti-IFNA1 ADCC Recombinant Antibody (Faralimomab), ADCC Enhanced | FuncS, IF, Neut, ELISA, FC, IP | ADCC enhanced antibody |
| AFC-TAB-074 | Afuco™ Anti-IFNA1 ADCC Recombinant Antibody (Rontalizumab), ADCC Enhanced | ELISA, FC, IP, FuncS, IF, Neut | ADCC enhanced antibody |
| AFC-TAB-H62 | Afuco™ Anti-IFNA1 ADCC Recombinant Antibody (Sifalimumab), ADCC Enhanced | IP, IF, FuncS, FC, Neut, ELISA | ADCC enhanced antibody |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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