Recombinant Mouse anti-Human NFATC2 Monoclonal antibody (25A10.D6.D2) (CAT#: MOB-2278CT)
Recombinant Mouse Monoclonall antibody to Human NFATC2, expressed in Chinese Hamster Ovary cells(CHO).
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Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line U-251 MG
(Immunofluorescent staining of human cell line U-251 MG shows localization to nucleoplasm & cytosol.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/8789/18_H10_2_selected.jpg
(Immunofluorescent staining of human cell line U-251 MG shows localization to nucleoplasm & cytosol.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/8789/18_H10_2_selected.jpg
Figure 2 High expression in appendix.
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/18567/43328_A_1_2_val_selected.jpg
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/18567/43328_A_1_2_val_selected.jpg
Figure 3 Lymph node
(Germinal center cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous Non-germinal center cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/8789/23788_A_7_8.jpg
(Germinal center cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous Non-germinal center cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/8789/23788_A_7_8.jpg
Figure 4 Cerebral cortex
(Endothelial cells Staining: Low Intensity: Moderate Quantity: <25% Location: Nuclear Glial cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous nuclear Neuronal cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous nuclear Neuropil Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/8789/23593_B_8_5.jpg
(Endothelial cells Staining: Low Intensity: Moderate Quantity: <25% Location: Nuclear Glial cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous nuclear Neuronal cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous nuclear Neuropil Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/8789/23593_B_8_5.jpg
Figure 5 Colon
(Endothelial cells Staining: Low Intensity: Weak Quantity: 75%-25% Enterocytes Staining: Low Intensity: Weak Quantity: 75%-25% Enterocytes - Goblet cells Staining: Low Intensity: Weak Quantity: 75%-25% Mucosal lymphoid cells Staining: Medium Intensity: Moderate)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/8789/23788_A_7_3.jpg
(Endothelial cells Staining: Low Intensity: Weak Quantity: 75%-25% Enterocytes Staining: Low Intensity: Weak Quantity: 75%-25% Enterocytes - Goblet cells Staining: Low Intensity: Weak Quantity: 75%-25% Mucosal lymphoid cells Staining: Medium Intensity: Moderate)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/8789/23788_A_7_3.jpg
Figure 6 RNA cell line category: Cell line enhanced (HDLM-2, HMC-1, SK-MEL-30, WM-115)
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000101096-NFATC2
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000101096-NFATC2
Specifications
- Immunogen
- Synthetic peptide: AISSPSGLAYPDDVLDYGL.The immunizing peptide corresponds to amino acid residues 51-69 of mouse NFAT1-A, B and C isoforms.The sequence of this N-terminal peptide is ~70% homologous with human NFAT1.
- Host Species
- Mouse
- Specificity
- Expressed in thymus, spleen, heart, testis, brain, placenta, muscle and pancreas.
- Species Reactivity
- Human
- Clone
- 25A10.D6.D2
- Applications
- Used for immunoassay techniques such as: Immunohistochemistry paraffin embedded sections; GSA; Immunocytochemistry; Immunoprecipitation; Western Blot
- Conjugate
- Unconjugated
Product Property
- Purity
- IgG fraction
- Format
- Liquid
- Buffer
- PBS with 0.05% sodium azide
- Storage
- Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Target
- Alternative Names
- NFATC2; nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2; NFAT1; NFATP; nuclear factor of activated T-cells, cytoplasmic 2; NF-ATc2; NFAT pre-existing subunit; T cell transcription factor NFAT1; T-cell transcription factor NFAT1; NFAT transcription complex, preexisting component; preexisting nuclear factor of activated T-cells 2; nuclear factor of activated T-cells, preexisting component;
- Gene ID
- 18019
- UniProt ID
- B5B2R5
- Function
- DNA binding; protein binding; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; transcription regulatory region DNA binding;
Related Resources
cAMP Signaling Pathway
Canonical Wnt Signaling Pathway
Non-Canonical Wnt Signaling Pathway
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-3148z | Mouse Anti-NFATC2 Recombinant Antibody (clone 37H4) | WB, IHC, IP, ELISA, IF | Mouse IgG1 |
| MRO-1083-CN | Recombinant Rabbit Anti-NFATc2 Monoclonal Antibody (JA11-08) | WB, IF, IHC, FC | Rabbit IgG |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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