Recombinant Mouse anti-Human NFATC2 Monoclonal antibody (25A10.D6.D2)
CAT#: MOB-2278CT
Recombinant Mouse Monoclonall antibody to Human NFATC2, expressed in Chinese Hamster Ovary cells(CHO).
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line U-251 MG
Immunofluorescent staining of human cell line U-251 MG shows localization to nucleoplasm & cytosol.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/8789/18_H10_2_selected.jpg
Normal Tissue
Figure 2 High expression in appendix.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/18567/43328_A_1_2_val_selected.jpg
Normal Tissue
Figure 3 Lymph node
Germinal center cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous Non-germinal center cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/8789/23788_A_7_8.jpg
Normal Tissue
Figure 4 Cerebral cortex
Endothelial cells Staining: Low Intensity: Moderate Quantity: <25% Location: Nuclear Glial cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous nuclear Neuronal cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous nuclear Neuropil Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/8789/23593_B_8_5.jpg
Normal Tissue
Figure 5 Colon
Endothelial cells Staining: Low Intensity: Weak Quantity: 75%-25% Enterocytes Staining: Low Intensity: Weak Quantity: 75%-25% Enterocytes - Goblet cells Staining: Low Intensity: Weak Quantity: 75%-25% Mucosal lymphoid cells Staining: Medium Intensity: Moderate
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/8789/23788_A_7_3.jpg
RNA Expression
Figure 6 RNA cell line category: Cell line enhanced (HDLM-2, HMC-1, SK-MEL-30, WM-115)
Cell lines ordered by descending RNA expression order
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000101096-NFATC2
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Specifications
- Immunogen
- Synthetic peptide: AISSPSGLAYPDDVLDYGL.The immunizing peptide corresponds to amino acid residues 51-69 of mouse NFAT1-A, B and C isoforms.The sequence of this N-terminal peptide is ~70% homologous with human NFAT1.
- Host Species
- Mouse
- Specificity
- Expressed in thymus, spleen, heart, testis, brain, placenta, muscle and pancreas.
- Species Reactivity
- Human
- Clone
- 25A10.D6.D2
- Applications
- Used for immunoassay techniques such as: Immunohistochemistry paraffin embedded sections; GSA; Immunocytochemistry; Immunoprecipitation; Western Blot
- Conjugate
- Unconjugated
Product Property
- Purity
- IgG fraction
- Format
- Liquid
- Buffer
- PBS with 0.05% sodium azide
- Storage
- Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Target
- Alternative Names
- NFATC2; nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2; NFAT1; NFATP; nuclear factor of activated T-cells, cytoplasmic 2; NF-ATc2; NFAT pre-existing subunit; T cell transcription factor NFAT1; T-cell transcription factor NFAT1; NFAT transcription complex, preexisting component; preexisting nuclear factor of activated T-cells 2; nuclear factor of activated T-cells, preexisting component;
- Gene ID
- 18019
- UniProt ID
- B5B2R5
- Function
- DNA binding; protein binding; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; transcription regulatory region DNA binding;
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Related Signaling Pathways
cAMP Signaling Pathway
Canonical Wnt Signaling Pathway
Non-Canonical Wnt Signaling Pathway
Downloadable Resources
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
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COA
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| MOB-3148z | Mouse Anti-NFATC2 Recombinant Antibody (clone 37H4) | WB, IHC, IP, ELISA, IF | Mouse IgG1 |
| MRO-1083-CN | Recombinant Rabbit Anti-NFATc2 Monoclonal Antibody (JA11-08) | WB, IF, IHC, FC | Rabbit IgG |
| CAT | Product Name | Application | Type |
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| MOR-2430 | Hi-Affi™ Recombinant Rabbit Anti-NFATC2 Monoclonal Antibody (DS2430AB) | WB | IgG |
| CAT | Product Name | Application | Type |
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| VS13-YC792 | CytoStream™ Rabbit Anti-NFATC2 Recombinant Antibody (VS13-YC792) | WB, ICC, IF, IHC-P, FC | Rabbit IgG |
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