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Recombinant Mouse anti-Human PTK2 Monoclonal antibody (N232) (CAT#: MOB-0669CT)

Recombinant Mouse monoclonal antibody to Human PTK2, expressed in Chinese Hamster Ovary cells(CHO).


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Specific Inquiry
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  • Conjugation:
  • Endotoxin:
  • Purity:
  • Fc Engineering:
  • Gene Expression
  • Datasheet
  • MSDS
  • COA
Subcellular Location and Protein Expression
Figure 1 IF staining of human cell line U-2 OS
Figure 1 IF staining of human cell line U-2 OS
(Immunofluorescent staining of human cell line U-2 OS shows localization to cytosol & focal adhesion sites.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/1842/if_selected.jpg
Figure 2 IHC staining of human urinary bladder
Figure 2 IHC staining of human urinary bladder
(Immunohistochemical staining of human urinary bladder shows moderate cytoplasmic and membranous positivity in urothelial cells)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/1842/66971_A_6_5_selected.jpg
Normal Tissue
Figure 3 Cerebral cortex
Figure 3 Cerebral cortex
(Neuronal cells
Staining: Low
Intensity: Weak
Quantity: 75%-25%
Location: Cytoplasmic/membranous
Neuropil
Staining: Low
Intensity: Weak
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/1842/66971_B_8_5.jpg
Figure 4 Colon
Figure 4 Colon
(Endothelial cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
Glandular cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
Peripheral nerve/ganglion
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/1842/66971_A_8_3.jpg
Figure 5 Liver
Figure 5 Liver
(Hepatocytes
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/1842/66971_A_9_4.jpg
Figure 6 Kidney
Figure 6 Kidney
(Cells in glomeruli
Staining: Low
Intensity: Weak
Quantity:>75%
Location: Cytoplasmic/membranous
Cells in tubules
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/1842/66971_A_9_5.jpg
Figure 7 Testis
Figure 7 Testis
(Cells in seminiferous ducts
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
Leydig cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/1842/66971_A_6_6.jpg
Figure 8 Breast
Figure 8 Breast
(Glandular cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
Myoepithelial cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/1842/66971_B_1_4.jpg
Figure 9 Lymph node
Figure 9 Lymph node
(Germinal center cells
Staining: Low
Intensity: Weak
Quantity: 75%-25%
Location: Cytoplasmic/membranous
Non-germinal center cells
Staining: Low
Intensity: Weak
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/1842/66971_A_9_8.jpg
RNA Expression
Figure 10 RNA cell line category: Low cell line specificity
Figure 10 RNA cell line category: Low cell line specificity
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000169398-PTK2/subcellular

Specifications

  • Immunogen
  • Synthetic peptide conjugated to KLH corresponding to amino acid residues around tyrosine 397 of human FAK. This peptide sequence has high homology to the conserved tyrosine site in rat and mouse FAK.
  • Host Species
  • Mouse
  • Species Reactivity
  • Human
  • Clone
  • N232
  • Applications
  • Used for immunoassay techniques such as: Enzyme-linked Immunosorbent Assay; Western Blot
  • Conjugate
  • Unconjugated

Product Property

  • Purity
  • Protein A purified
  • Format
  • Liquid
  • Buffer
  • Preservative: 0.05% Sodium Azide Constituents: 50% Glycerol, PBS, 1mg/ml BSA
  • Storage
  • Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

Target

  • Alternative Names
  • PTK2; protein tyrosine kinase 2; FAK; FADK; FAK1; FRNK; PPP1R71; p125FAK; pp125FAK; focal adhesion kinase 1; FADK 1; PTK2 protein tyrosine kinase 2; FAK-related non-kinase polypeptide; focal adhesion kinase isoform FAK-Del33; focal adhesion kinase-related nonkinase; protein phosphatase 1 regulatory subunit 71; protein phosphatase 1, regulatory subunit 71;
  • Function
  • ATP binding; JUN kinase binding; SH2 domain binding; non-membrane spanning protein tyrosine kinase activity; nucleotide binding; protein binding; protein kinase activity; protein kinase binding; protein tyrosine kinase activity; signal transducer activity

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

See other products for "PTK2"

Recombinant Antibody

CAT Product Name Application Type
MOB-2031z Mouse Anti-PTK2 Recombinant Antibody (clone 11B8) WB, ELISA, ICC, IHC Mouse IgG1
MRO-0564-CN Recombinant Rabbit Anti-PTK2 Monoclonal Antibody (CBACN-222) WB, IF, IHC, IP, FC Rabbit IgG
ZG-0329J Mouse Anti-PTK2 Recombinant Antibody (ZG-0329J) WB, ELISA Mouse IgG
ZG-0330J Mouse Anti-PTK2 Recombinant Antibody (ZG-0330J) WB, ELISA Mouse IgG
ZG-0331J Mouse Anti-PTK2 Recombinant Antibody (ZG-0331J) WB, IHC, IF, ELISA Mouse IgG

Chicken IgY Antibody

CAT Product Name Application Type
BRD-0748MZ Chicken Anti-FAK1 Polyclonal IgY ELISA, IHC, IP, WB Chicken antibody

Rabbit Monoclonal Antibody

CAT Product Name Application Type
MOR-2924 Hi-Affi™ Recombinant Rabbit Anti-PTK2 Monoclonal Antibody (DS2924AB) ICC, WB IgG
MOR-4573 Hi-Affi™ Recombinant Rabbit Anti-PTK2 Monoclonal Antibody (TH85DS) WB, IF, ICC, FC IgG
MOR-4678 Hi-Affi™ Recombinant Rabbit Anti-PTK2 Monoclonal Antibody (TH192DS) WB, IF, ICC, IHC-P, FC, ELISA IgG
MOR-4679 Hi-Affi™ Recombinant Rabbit Anti-PTK2 Monoclonal Antibody (TH193DS) IF, ICC, IHC-P, FC IgG
MOR-4680 Hi-Affi™ Recombinant Rabbit Anti-PTK2 Monoclonal Antibody (TH194DS) WB, IF, ICC, FC IgG

MHC Tetramer for Cancer

CAT Product Name Application Type
MHC-LC2719 PE-A*02:01/Human PTK2 (SLDLASLIL) MHC Tetramer FCM
MHC-LC2720 PE-A*02:07/Human PTK2 (SLDLASLIL) MHC Tetramer FCM
MHC-LC4514 PE-Mamu-A1*001:01/Human PTK2 (LTAAHALAV) MHC Tetramer FCM

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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