Anti-Human Phosphatidylserine Recombinant Antibody (TAB-175)

Customer Review

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Rachel Adams
25.Apr,23

Excellent for Phosphatidylserine

The Anti-Human Phosphatidylserine Therapeutic Antibody (Bavituximab) has been excellent for our phosphatidylserine studies. Its quality is top-notch, providing clear and reliable results. This product has significantly improved the accuracy of our experiments and saved us a lot of troubleshooting time.

Michael Clark
07.Aug,22

Effective and Dependable

We incorporated this antibody into our phosphatidylserine protocols, and it has been a great asset. The consistency and reliability are impressive, allowing for accurate and reproducible results. The reliable performance has made it an invaluable tool in our lab.

Laura Harris
03.Jun,21

Consistent High-Quality Results

This antibody has proven to be consistent and high-quality in our phosphatidylserine procedures. The reproducible results have significantly improved our experiments, making it a crucial part of our research toolkit. The consistent performance has greatly enhanced our data quality.

Q&As

1. Is the anti-Human Phosphatidylserine therapeutic antibody Bavituximab suitable for use in Western blotting?

   A: Yes, the anti-Human Phosphatidylserine therapeutic antibody Bavituximab (TAB-175) is suitable for use in Western blotting. It provides specific binding to phosphatidylserine, allowing for reliable detection in Western blot assays.

2. What are the storage recommendations for the anti-Human Phosphatidylserine therapeutic antibody Bavituximab?

   A: The recommended storage condition for the anti-Human Phosphatidylserine therapeutic antibody Bavituximab (TAB-175) is at -20°C or lower. For short-term storage, it can be kept at 2-8°C. To ensure stability, avoid repeated freeze-thaw cycles.

3. Can the anti-Human Phosphatidylserine therapeutic antibody Bavituximab be used in immunoprecipitation assays?

   A: Yes, the anti-Human Phosphatidylserine therapeutic antibody Bavituximab (TAB-175) can be used in immunoprecipitation assays. It provides specific binding to phosphatidylserine, enabling the successful precipitation of the target molecule from complex mixtures.

4. Is the anti-Human Phosphatidylserine therapeutic antibody Bavituximab effective in ELISA applications?

   A: Yes, the anti-Human Phosphatidylserine therapeutic antibody Bavituximab (TAB-175) is effective in ELISA applications. It has been validated for use in such assays and provides reliable detection of phosphatidylserine.

5. What is the optimal dilution for using the anti-Human Phosphatidylserine therapeutic antibody Bavituximab in immunofluorescence?

   A: The optimal dilution for using the anti-Human Phosphatidylserine therapeutic antibody Bavituximab (TAB-175) in immunofluorescence is typically 1:100 to 1:500. It is advisable to perform a dilution series to determine the best working concentration for your specific experimental conditions.

View the frequently asked questions answered by Creative Biolabs Support.

Citations

1. Laggner, Maria, et al. "The secretome of irradiated peripheral blood mononuclear cells attenuates activation of mast cells and basophils." EBioMedicine 81 (2022). https://doi.org/10.1016/j.ebiom.2022.104093
   The study focused on the anti-allergic potential of the secretome of gamma-irradiated peripheral blood mononuclear cells (PBMCsec) in reducing the activation of mast cells and basophils, which are key players in allergic reactions. Researchers used both in vitro and in vivo models to investigate how PBMCsec influences mast cell degranulation and basophil activation, finding that PBMCsec effectively attenuates the activation of these immune cells. Specifically, topical application of PBMCsec on mouse ears significantly reduced tissue swelling caused by mast cell degranulation, while in vitro studies showed that PBMCsec inhibited mediator release from human dermal mast cells and basophils upon allergen stimulation. Transcriptomic analyses revealed that PBMCsec downregulates genes involved in immune cell activation and degranulation, underscoring its potential as an anti-allergic treatment.
   Creative Biolabs provided the anti-human phosphatidylserine antibody Bavituximab (Cat#: TAB-175) used in this study. This antibody was essential for the blocking experiments that aimed to determine the role of phosphatidylserine (PS) in PBMCsec-mediated inhibition of basophil activation. The use of Bavituximab helped to elucidate the mechanisms by which PBMCsec prevents immune cell degranulation, thereby supporting the identification of PS and other lipid species as the active components responsible for the anti-allergic effects observed.

Cite This Product

To accurately reference this product in your publication, please use the following citation information:

(Creative Biolabs Cat# TAB-175, RRID: AB_3111848)

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Biosimilar Overview

Please refer to Bavituximab Overview to learn more about the mechanism of action, clinical projects, and approved drugs of Bavituximab.

Downloadable Resources

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Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Datasheet

MSDS

COA

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Protocol & Troubleshooting

We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.

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