Human Anti-IL12 Recombinant Antibody (clone CNTO1275); Fab Fragment
CAT#: PFBL-597
Recombinant Humanized Antibody (CNTO-1275) Fab Fragment is specific to IL-12, expressed in Chinese Hamster Ovary cells (CHO). This Fab fragment prevents IL-12 and IL-23 bioactivity by preventing their interaction with the cell surface IL-12Rβ1 protein, thus effectively neutralizing both IL-12 (Th1)-mediated and IL-23 (Th17)-mediated cellular responses.
Specifications
- Immunogen
- Human interleukin 12B
- Host Species
- Human
- Derivation
- Humanized
- Type
- Humanized Fab
- Specificity
- Human IL12
- Species Reactivity
- Human
- Clone
- CNTO1275
- Applications
- Neut, ELISA
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- IL12B; interleukin 12B; CLMF; NKSF; CLMF2; IMD28; IMD29; NKSF2; IL-12B; interleukin-12 subunit beta; CLMF p40; IL-12 subunit p40; IL12, subunit p40; interleukin 12, p40; interleukin-12 beta chain; NK cell stimulatory factor chain 2; cytotoxic lymphocyte maturation factor 40 kDa subunit; natural killer cell stimulatory factor, 40 kD subunit; interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40)
- Gene ID
- 3593
- UniProt ID
- P29460
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Related Diseases
Asthma
Inflammatory Bowel Diseases
Downloadable Resources
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "Clone CNTO1275"
- CAT
- Product Name
See other products for "IL12"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PSBL-597 | Human Anti-IL12 Recombinant Antibody (clone CNTO1275); scFv Fragment | Neut, ELISA | Humanized scFv |
| HPAB-1551WJ-S(P) | Human Anti-IL12 Recombinant Antibody; scFv Fragment (clone 70-1) | ELISA, WB | Human scFv |
| HPAB-1552WJ-S(P) | Human Anti-IL12 Recombinant Antibody; scFv Fragment (clone 101-11) | ELISA, WB | Human scFv |
| HPAB-1554WJ-S(P) | Human Anti-IL12 Recombinant Antibody; scFv Fragment (clone 78-34) | ELISA, WB | Human scFv |
| HPAB-1585WJ-S(P) | Human Anti-IL12 Recombinant Antibody; scFv Fragment (clone J695) | ELISA, WB | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-1151CQ | Rat Anti-IL12 Recombinant Antibody (clone 20C2) | Block, ELISA, WB | Rat IgG1 |
| NEUT-1153CQ | Rat Anti-IL12 Recombinant Antibody (clone C8.6) | Block, ELISA, WB | Rat IgG1 |
| NEUT-1162CQ | Mouse Anti-IL12 Recombinant Antibody (clone B-T21) | ELISA, Block | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-1152CQ | Mouse Anti-IL12 Recombinant Antibody (clone 31H23) | Neut, WB | Mouse IgG1 |
| NEUT-1154CQ | Mouse Anti-IL12 Recombinant Antibody (clone CBL092) | Neut, WB, IHC | Mouse IgG1 |
| NEUT-1155CQ | Mouse Anti-IL12 Recombinant Antibody (clone CBL244) | ELISA, Neut | Mouse IgG1 |
| NEUT-1156CQ | Rat Anti-IL12 Recombinant Antibody (clone 9A5) | Block, ELISA, ICC, IF, IHC, IP, WB | Rat IgG2b |
| NEUT-1157CQ | Rat Anti-Il12 Recombinant Antibody (NEUT-1157CQ) | WB, IP, Neut, FC | Rat IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0844-FY | Human Anti-IL12 Recombinant Antibody (clone Y61) | Inhib, WB, IHC, ELISA, FuncS | Human IgG |
| MOB-Z041-YC | Human Anti-IL12 Recombinant Antibody (clone DEC.YC041) | WB, ELISA, IF, FC | Human IgG1, κ |
| HPAB-1551WJ | Human Anti-IL12 Recombinant Antibody (clone 70-1) | ELISA, WB | Human IgG1 |
| HPAB-1552WJ | Human Anti-IL12 Recombinant Antibody (clone 101-11) | ELISA, WB | Human IgG1 |
| HPAB-1554WJ | Human Anti-IL12 Recombinant Antibody (clone 78-34) | ELISA, WB | Human IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0844-FY-S(P) | Human Anti-IL12 Recombinant Antibody (clone Y61); Fab Fragment | Neut | Human Fab |
| HPAB-1551WJ-F(E) | Human Anti-IL12 Recombinant Antibody; Fab Fragment (clone 70-1) | ELISA, WB | Human Fab |
| HPAB-1552WJ-F(E) | Human Anti-IL12 Recombinant Antibody; Fab Fragment (clone 101-11) | ELISA, WB | Human Fab |
| HPAB-1554WJ-F(E) | Human Anti-IL12 Recombinant Antibody; Fab Fragment (clone 78-34) | ELISA, WB | Human Fab |
| HPAB-1585WJ-F(E) | Human Anti-IL12 Recombinant Antibody; Fab Fragment (clone J695) | ELISA, WB | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-FY123 | Human Anti-IL12 (clone Y61) scFv-Fc Chimera | Neut | Human IgG1, scFv-Fc |
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