Human Anti-IL12 Recombinant Antibody (clone CNTO1275); Fab Fragment (CAT#: PFBL-597)
Recombinant Humanized Antibody (CNTO-1275) Fab Fragment is specific to IL-12, expressed in Chinese Hamster Ovary cells (CHO). This Fab fragment prevents IL-12 and IL-23 bioactivity by preventing their interaction with the cell surface IL-12Rβ1 protein, thus effectively neutralizing both IL-12 (Th1)-mediated and IL-23 (Th17)-mediated cellular responses.
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Custom Production
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
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Specifications
- Immunogen
- Human interleukin 12B
- Host Species
- Human
- Derivation
- Humanized
- Type
- Humanized Fab
- Specificity
- Human IL12
- Species Reactivity
- Human
- Clone
- CNTO1275
- Applications
- Neut, ELISA
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- IL12B; interleukin 12B; CLMF; NKSF; CLMF2; IMD28; IMD29; NKSF2; IL-12B; interleukin-12 subunit beta; CLMF p40; IL-12 subunit p40; IL12, subunit p40; interleukin 12, p40; interleukin-12 beta chain; NK cell stimulatory factor chain 2; cytotoxic lymphocyte maturation factor 40 kDa subunit; natural killer cell stimulatory factor, 40 kD subunit; interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40)
- Gene ID
- 3593
- UniProt ID
- P29460
Related Resources
Asthma
Inflammatory Bowel Diseases
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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ScFv-Fc Chimera Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PSBL-597 | Human Anti-IL12 Recombinant Antibody (clone CNTO1275); scFv Fragment | Neut, ELISA | Humanized scFv |
| HPAB-1551WJ-S(P) | Human Anti-IL12 Recombinant Antibody; scFv Fragment (clone 70-1) | ELISA, WB | Human scFv |
| HPAB-1552WJ-S(P) | Human Anti-IL12 Recombinant Antibody; scFv Fragment (clone 101-11) | ELISA, WB | Human scFv |
| HPAB-1554WJ-S(P) | Human Anti-IL12 Recombinant Antibody; scFv Fragment (clone 78-34) | ELISA, WB | Human scFv |
| HPAB-1585WJ-S(P) | Human Anti-IL12 Recombinant Antibody; scFv Fragment (clone J695) | ELISA, WB | Human scFv |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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