Afuco™ Anti-Human IL17RB ADCC Recombinant Antibody, ADCC Enhanced (CAT#: AFC-385CL)
Anti-IL17RB ADCC Enhanced Antibody is an ADCC enhanced antibody produced by our Afuco™ platform. The antibody which bind interleukin-17 receptor B may be useful in therapy, such as the treatment of asthma, ulcerative colitis or Crohn's disease.
Specific Inquiry
Subcellular Location and Protein Expression
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line OE19
(Immunofluorescent staining of human cell line OE19 shows localization to plasma membrane & vesicles.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/5482/2038_F4_1_selected.jpg
(Immunofluorescent staining of human cell line OE19 shows localization to plasma membrane & vesicles.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/5482/2038_F4_1_selected.jpg
Figure 2 Cerebral cortex
(Neuronal cells
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/5482/15814_B_7_5.jpg
(Neuronal cells
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/5482/15814_B_7_5.jpg
Figure 3 Adrenal gland
(Glandular cells
Staining:High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/5482/15814_B_4_5.jpg
(Glandular cells
Staining:High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/5482/15814_B_4_5.jpg
Figure 4 Liver
(Hepatocytes
Staining:High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/5482/15814_A_8_4.jpg
(Hepatocytes
Staining:High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/5482/15814_A_8_4.jpg
Figure 5 Kidney
(Distal tubules
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
Proximal tubules (cell body)
Staining:High
Intensity: Strong
Quantity:>75%)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/5482/15814_A_8_5.jpg
(Distal tubules
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
Proximal tubules (cell body)
Staining:High
Intensity: Strong
Quantity:>75%)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/5482/15814_A_8_5.jpg
Figure 6 Testis
(Leydig cells
Staining:High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/5482/15814_A_4_6.jpg
(Leydig cells
Staining:High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/5482/15814_A_4_6.jpg
Figure 7 RNA cell line category: Cell line enhanced (CACO-2, Hep G2, OE19)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000056736-IL17RB
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000056736-IL17RB
Specifications
- Host Species
- Mouse
- Derivation
- Mouse
- Type
- ADCC enhanced antibody
- Species Reactivity
- Human
- Related Disease
- Asthma
Product Property
- Purity
- >90% assessed by SDS-PAGE
- Storage
- Store at -20°C. Avoid multiple freeze/thaw cycles.
Target
- Alternative Names
- IL17RB; interleukin 17 receptor B; CRL4; EVI27; IL17BR; IL17RH1; interleukin-17 receptor B; IL-17RB; IL-17Rh1; IL-17B receptor; IL-17 receptor B; cytokine receptor CRL4; IL-17 receptor homolog 1; cytokine receptor-like 4; interleukin 17B receptor; interleukin-17B receptor; interleukin 17 receptor homolog 1
- Gene ID
- 55540
- UniProt ID
- Q9NRM6
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Single Domain Antibody Products
IgG Antibody Products
Neutralizing Antibody Products
ScFv Antibody Products
Fab Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NAB-1426-VHH | Recombinant Anti-Human IL17RB VHH Single Domain Antibody | WB, IP, ICC, FC, FA | Llama VHH |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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