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    Human Anti-IL33 Recombinant Antibody; Fab Fragment (TAB-0460CL-F(E)) (CAT#: TAB-0460CL-F(E))

    The antibody is a recombinant human antibody Fab fragment that binds to the human interleukin 33 (IL33), which is a important cytokine that binds to and signals through the IL1RL1/ST2 receptor. The antibody was purified by affinity chromatography. It specifically binds to human IL33 and can be potentially used in the research of disease of immune system.

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    • Fc Engineering:

    • Modalities:

    Custom Production

    We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.

    Sequences:
    Isotype :
    Purity :
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    Other Requirements:
    We require custom production
    • Gene Expression
    • Datasheet
    • MSDS
    • COA
    Subcellular Location and Protein Expression
    Figure 1 IF staining of human cell line EFO-21
    Figure 1 IF staining of human cell line EFO-21
    (Immunofluorescent staining of human cell line EFO-21 shows localization to nucleoplasm & vesicles.)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/22899/1907_B1_4_selected.jpg
    Figure 2 IHC staining of human colon
    Figure 2 IHC staining of human colon
    (Immunohistochemical staining of human colon shows nuclear positivity in endothelial cells.)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/24426/53688_A_7_3_selected.jpg
    Figure 3 IF staining of human cell line BJ
    Figure 3 IF staining of human cell line BJ
    (Immunofluorescent staining of human cell line BJ shows localization to nucleoplasm.)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/22899/1936_B1_1_red_green.jpg
    Figure 4 IF staining of human cell line U-2 OS
    Figure 4 IF staining of human cell line U-2 OS
    (Immunofluorescent staining of human cell line U-2 OS shows localization to nucleoplasm.)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/22899/1953_C1_1_red_green.jpg
    Normal Tissue
    Figure 5 Cerebral cortex
    Figure 5 Cerebral cortex
    (Endothelial cells
    Staining:Medium
    Intensity: Moderate
    Quantity: 75%-25%
    Location: Cytoplasmic/membranous nuclear)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/7057/18488_B_8_5.jpg
    Figure 6 Colon
    Figure 6 Colon
    (Endothelial cells
    Staining:High
    Intensity: Strong
    Quantity:>75%
    Location: Nuclear)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/7057/18488_A_7_3.jpg
    Figure 7 Endometrium
    Figure 7 Endometrium
    (Cells in endometrial stroma
    Staining:High
    Intensity: Strong
    Quantity: 75%-25%
    Location: Nuclear
    Glandular cells
    Staining:High
    Intensity: Strong
    Quantity: 75%-25%
    Location: Nuclear)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/7057/18488_B_4_3.jpg
    Figure 8 Lymph node
    Figure 8 Lymph node
    (Non-germinal center cells
    Staining:Medium
    Intensity: Strong
    Quantity: <25%
    Location: Nuclear)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/7057/18488_A_7_8.jpg
    RNA Expression
    Figure 9 RNA cell line category: Group enriched (hTERT-RPE1, U-2197)
    Figure 9 RNA cell line category: Group enriched (hTERT-RPE1, U-2197)
    (Cell lines ordered by descending RNA expression order.)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000137033-IL33

    Specifications

    • Host Species
    • Human
    • Type
    • Human Fab
    • Specificity
    • Human
    • Species Reactivity
    • Human
    • Applications
    • Neut, FuncS
    • Related Disease
    • IL-33 related diseases, such as inflammation

    Product Property

    • Purity
    • >95% as determined by SDS-PAGE
    • Concentration
    • Please refer to the vial label for the specific concentration.
    • Buffer
    • PBS
    • Preservative
    • No preservatives
    • Storage
    • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

    Target

    • Alternative Names
    • IL33; interleukin 33; DVS27; IL1F11; NF-HEV; NFEHEV; C9orf26; interleukin-33; IL-33; IL-1F11; DVS27-related protein; interleukin-1 family member 11; nuclear factor for high endothelial venules; nuclear factor from high endothelial venules

    Product Notes

    This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

    • Increased sensitivity
    • Confirmed specificity
    • High repeatability
    • Excellent batch-to-batch consistency
    • Sustainable supply
    • Animal-free production

    See more details about Hi-Affi™ recombinant antibody benefits.

    Downloads

    Download resources about recombinant antibody development and antibody engineering to boost your research.

    See other products for "Il33"

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    Please select product type
    Single Domain Antibodies Human Antibodies Chimeric Antibodies Neutralizing Antibodies Rabbit Monoclonal Antibodies ScFv Antibodies IgG Antibodies Fab Antibodies ScFv-Fc Chimeras IHC Kits & Antibodies
    CAT Product Name Application Type
    NAB-769-sdAb Recombinant Anti-Mouse Il33 VHH Single Domain Antibody ICC, ChiP, FC, FA Llama VHH

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    For Research Use Only. Not For Clinical Use.

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