This immunotoxin was achieved by conjugating/fusing the Anti-IgM monoclonal antibody to ricin toxin. It was expressed in CHO and purified with affinity chromatography. The immunotoxin selectively binds to leptomeningeal neoplasia cell. Then the ricin A chain is incorporated into the cell by receptor-mediated endocytosis, blocking ribosomal protein synthesis and ultimately leading to cell death. It was designed for treatment of leptomeningeal neoplasia.
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
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CAT | Product Name | Application | Type |
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NAB-2642-VHH | Recombinant Anti-human IgM VHH Single Domain Antibody | IHC, ICC, IP, ChiP, Neut | Llama VHH |
NABG-116 | Llama Anti-human IgM VHH Single Domain Antibody [Biotin] | ELISA, WB, BLI, SPR |
CAT | Product Name | Application | Type |
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BRD-0269MZ | Chicken Anti-Human IgM Polyclonal IgY | WB | Chicken antibody |
CAT | Product Name | Application | Type |
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NEUT-373CQ | Mouse Anti-IgM Recombinant Antibody (clone M15/8) | ELISA, FC, IHC-Fr, IP, Block | Mouse IgG1, κ |
CAT | Product Name | Application | Type |
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MOR-1778 | Rabbit Anti-IgM Recombinant Antibody (clone DS1778AB) | ICC, IHC, FC, ELISA | Rabbit IgG |
CAT | Product Name | Application | Type |
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MOB-076LC | Mouse Anti-IgM Recombinant Antibody (clone 12M) | ELISA | Mouse IgG |
MOB-190CQ | Armenian Hamster IgM Isotype Control Antibody | WB, IP, ICC, IF, FuncS, FC, ICFC | Armenian Hamster IgM |
MOB-189CQ | Armenian Hamster IgG Isotype Control Antibody | WB, IP, ICC, IF, FuncS, FC, ICFC | Armenian Hamster IgG |
FN-064CQ | Mouse Anti-IGM Recombinant Antibody (clone UCHB1) | ELISA, FC, FuncS | Mouse IgG1 |
VS-0224-XY70 | Mouse Anti-IgM Recombinant Antibody (clone NRBM) | FC, IHC-Fr | Mouse IgG1 |
CAT | Product Name | Application | Type |
---|---|---|---|
FAMAB-0134-CN-S(P) | Mouse Anti-IgM Recombinant Antibody (clone DA4.4); scFv Fragment | ELISA | Mouse scFv |
FAMAB-0135-CN-S(P) | Rat Anti-IgM Recombinant Antibody (clone Bet2); scFv Fragment | ELISA | Rat scFv |
HPAB-1286WJ-S(P) | Human Anti-IgM Recombinant Antibody (clone MSI19D10); scFv Fragment | ELISA, WB | Human scFv |
HPAB-1287WJ-S(P) | Human Anti-IgM Recombinant Antibody (clone CB2bG8); scFv Fragment | ELISA, WB | Human scFv |
HPAB-1288WJ-S(P) | Human Anti-IgM Recombinant Antibody (clone AKJR4); scFv Fragment | ELISA, WB | Human scFv |
CAT | Product Name | Application | Type |
---|---|---|---|
FAMAB-0134-CN-F(E) | Mouse Anti-IgM Recombinant Antibody (clone DA4.4); Fab Fragment | ELISA | Mouse Fab |
FAMAB-0135-CN-F(E) | Rat Anti-IgM Recombinant Antibody (clone Bet2); Fab Fragment | ELISA | Rat Fab |
HPAB-1286WJ-F(E) | Human Anti-IgM Recombinant Antibody (clone MSI19D10); Fab Fragment | ELISA, WB | Human Fab |
HPAB-1287WJ-F(E) | Human Anti-IgM Recombinant Antibody (clone CB2bG8); Fab Fragment | ELISA, WB | Human Fab |
HPAB-1288WJ-F(E) | Human Anti-IgM Recombinant Antibody (clone AKJR4); Fab Fragment | ELISA, WB | Human Fab |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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