Anti-Human KCNA3 Single Domain Antibody, Research Grade Biosimilar (CAT#: TAB-466CL)
Recombinant Human monoclonal Single Domain Antibody expressed in E. coli binding to Human KCNA3. The anti-Kv1.3 single domain antibodies, something that has historically been difficult to achieve with other drug modalities such as small molecules and peptide-based toxins. The Kv1.3 ion channel represents an important target in inflammatory disease as it helps control ion influx required for activation of T lymphocytes.
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Custom Production
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
We require custom production
Normal Tissue
RNA Expression
Figure 1 IHC staining of human cerebral cortex
(Immunohistochemical staining of human cerebral cortex shows strong cytoplasmic positivity in Astrocytes.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/16625/ihc_selected.jpg
(Immunohistochemical staining of human cerebral cortex shows strong cytoplasmic positivity in Astrocytes.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/16625/ihc_selected.jpg
Figure 2 Cerebral cortex
(Glial cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/16625/39156_B_9_5.jpg
(Glial cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/16625/39156_B_9_5.jpg
Figure 3 RNA cell line category: Cell line enhanced (HDLM-2, Karpas-707, U-266/70, U-266/84)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000177272-KCNA3
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000177272-KCNA3
Specifications
- Host Species
- Human
- Type
- Single Domain Antibody
- Species Reactivity
- Human
- Related Disease
- Inflammatory Diseases
Product Property
- Purity
- >95%, by SDS-PAGE, under reducing conditions
- Storage
- ≥1 year at -20°C. If the reconstituted antibody cannot be used within two weeks, it should be aliquoted into smaller vials and stored at -20°C
Target
- Alternative Names
- KCNA3; potassium channel, voltage gated shaker related subfamily A, member 3; MK3; HGK5; HLK3; PCN3; HPCN3; KV1.3; HUKIII; potassium voltage-gated channel subfamily A member 3; potassium channel 3; type n potassium channel; voltage-gated K(+) channel HuKI
- Gene ID
- 3738
- UniProt ID
- P22001
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Humanized Antibody Products
IgG Antibody Products
ScFv-Fc Chimera Products
Extracellular Vesicle (EV) Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0634CL | Human Anti-KCNA3 Recombinant Antibody (TAB-0634CL) | ELISA | Humanized IgG |
| TAB-0634CL-S(P) | Human Anti-KCNA3 Recombinant Antibody; scFv Fragment (TAB-0634CL-S(P)) | ELISA | Humanized scFv |
| TAB-0634CL-F(E) | Human Anti-KCNA3 Recombinant Antibody; Fab Fragment (TAB-0634CL-F(E)) | ELISA | Humanized Fab |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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