Mouse Anti-LDLR Recombinant Antibody (clone 12G4); scFv Fragment
CAT#: HPAB-0095-YC-S(P)
Provided is a monoclonal antibody raised against the human LDL (Low Density Lipoprotein) receptor, binding to the peptide corresponding to amino acids 195-222 in the peptide sequence for the human LDL receptor; to the use thereof as a drug; to a pharmaceutical composition containing this antibody; and to the use thereof in immunohistochemical analyses of cancerous, healthy, or cirrhotic tissues, in Western-Blot or ELISA analyses, or in in vivo quantification tests.
Gene Expression
Normal Tissue
Figure 1 IHC staining of human liver
Immunohistochemical staining of human liver shows strong cytoplasmic positivity in hepatocytes.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/9647/ihc_selected.jpg
Normal Tissue
Figure 2 IHC staining of human colon
Immunohistochemical staining of human colon shows moderate cytoplasmic positivity in glandular cells.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/13159/29364_A_8_3_selected.jpg
Normal Tissue
Figure 3 Cerebral cortex
Neuronal cells
Staining: Low
Intensity: Moderate
Quantity: <25%
Location: Cytoplasmic/membranou
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/9647/25258_B_7_5.jpg
Normal Tissue
Figure 4 Stomach
Glandular cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/9647/25258_A_6_1.jpg
Normal Tissue
Figure 5 Kidney
Cells in tubules
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/9647/25258_A_7_5.jpg
Normal Tissue
Figure 6 Testis
Leydig cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/9647/25258_A_4_6.jpg
Normal Tissue
Figure 7 Lymph node
Non-germinal center cells
Staining: Low
Intensity: Moderate
Quantity: <25%
Location: Cytoplasmic/membranous nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/13159/29364_A_9_8.jpg
RNA Expression
Figure 8 RNA cell line category: Low cell line specificity
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000130164-LDLR
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Specifications
- Immunogen
- Amino acids 195-222 in the peptide sequence for the human LDL receptor
- Host Species
- Mouse
- Type
- Mouse scFv
- Specificity
- Human MUC1
- Species Reactivity
- Human, Mouse, Rat
- Clone
- 12G4
- Applications
- ELISA, WB, IHC, FuncS
- Related Disease
- Cancer
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
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Related Diseases
Cushing Syndrome
Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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Protocol & Troubleshooting
We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.
See other products for "Clone 12G4"
- CAT
- Product Name
See other products for "LDLR"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-0029MZ | Recombinant Mouse Anti-Human LDLR Antibody (clone JgG-C8) | WB, FC, IF | Mouse antibody |
| MOB-0040MZ | Recombinant Mouse Anti-Human Lectin-like Oxidized LDL receptor-1 (sLOX-1) Soluble form Antibody (clone C019M) | ELISA | Mouse antibody |
| HPAB-0095-YC | Mouse Anti-LDLR Recombinant Antibody (clone 12G4) | ELISA, WB, IHC, FuncS | Mouse IgG |
| MRO-0922-CN | Recombinant Rabbit Anti-LDLR Monoclonal Antibody (CBACN-345) | WB, IF, IHC, FC | Rabbit IgG |
| VS11-QX101 | Mouse Anti-LDLR Recombinant Antibody (clone C7) | FC, IP, WB, Inhib, IF | Mouse IgG2b, κ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| BRD-0323MZ | Chicken Anti-LDLR Polyclonal IgY | Anti-LDLR antibody produced in chicken is suitable for WBting analysis at a dilution of 1:500, for tissue or cell staining at a dilution of 1:200. | Chicken antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-2033 | Hi-Affi™ Recombinant Rabbit Anti-LDLR Monoclonal Antibody (DS2033AB) | ICC, IF, WB, IP, FC, IHC-P | IgG |
| MOR-0086-FY | Rabbit Anti-LDLR Recombinant Antibody (clone AFY0057) | FC, ICC, IHC, WB | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0095-YC-F(E) | Mouse Anti-LDLR Recombinant Antibody (clone 12G4); Fab Fragment | ELISA, WB, IHC, FuncS | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-YC636 | Recombinant Anti-LDLR Vesicular Antibody, EV Displayed (VS-0425-YC636) | ELISA, FC, Cell-uptake |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY3975 | Anti-LDLR Immunohistochemistry Kit | IHC |
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