Human Anti-LINGO1 Recombinant Antibody; Fab Fragment (PFBL-627)
CAT#: PFBL-627
This product is a recombinant human antibody Fab fragment that recognizes LINGO1, a surface glycoprotein selectively expressed in neurons and oligodendrocytes in the CNS. The antibody can promote oligodendrocyte differentiation and myelination.
Gene Expression
Subcellular Location and Protein Expression
Figure 1 IF staining of human cell line HEK 293
Immunofluorescent staining of human cell line HEK 293 shows localization to plasma membrane.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/74653/1466_F12_2_selected.jpg
Subcellular Location and Protein Expression
Figure 2 IF staining of human cell line AF22
Immunofluorescent staining of human cell line AF22 shows localization to plasma membrane.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/74653/1595_E7_2_blue_red_green.jpg
Subcellular Location and Protein Expression
Figure 3 IF staining of human cell line U-2 OS
Immunofluorescent staining of human cell line U-2 OS shows localization to plasma membrane.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/74653/1521_F12_2_blue_red_green.jpg
RNA Expression
Figure 4 RNA cell line category: Cell line enhanced (AF22, AN3-CA, HAP1, HEK93, MCF7, NTERA-2, SuSa)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000169783-LINGO1
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Specifications
- Immunogen
- Human leucine rich repeat and Ig domain containing 1
- Host Species
- Human
- Derivation
- Human
- Type
- Human Fab
- Specificity
- Human LINGO1
- Species Reactivity
- Human
- Applications
- ELISA
Product Property
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- LINGO1; leucine rich repeat and Ig domain containing 1; LERN1; LRRN6A; UNQ201; leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1; leucine rich repeat neuronal 6A; leucine-rich repeat neuronal protein 1; leucine-rich repeat and immunoglobulin domain-containing protein 1
- Gene ID
- 84894
- UniProt ID
- Q96FE5
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Downloadable Resources
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "LINGO1"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NAB-1666-VHH | Recombinant Anti-Human LINGO1 VHH Single Domain Antibody | Neut, ChiP, IP, FUNC | Llama VHH |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PFBL-628 | Human Anti-LINGO1 Recombinant Antibody; Fab Fragment (PFBL-628) | WB, IF, FuncS | Human Fab |
| HPAB-1292-FY-S(P) | Human Anti-LINGO1 Recombinant Antibody; scFv Fragment (HPAB-1292-FY-S(P)) | WB, ELISA | Human scFv |
| HPAB-1576-FY-S(P) | Human Anti-LINGO1 Recombinant Antibody; scFv Fragment (HPAB-1576-FY-S(P)) | WB, ELISA, IF | Human scFv |
| HPAB-1577-FY-S(P) | Human Anti-LINGO1 Recombinant Antibody; scFv Fragment (HPAB-1577-FY-S(P)) | WB, ELISA, IF | Human scFv |
| HPAB-1578-FY-S(P) | Human Anti-LINGO1 Recombinant Antibody; scFv Fragment (HPAB-1578-FY-S(P)) | WB, ELISA, IF | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PSBL-627 | Human Anti-LINGO1 Recombinant Antibody; scFv Fragment (PSBL-627) | ELISA | Human scFv |
| PSBL-628 | Human Anti-LINGO1 Recombinant Antibody; scFv Fragment (PSBL-628) | WB, IF, FuncS | Human scFv |
| HPAB-1292-FY-F(E) | Human Anti-LINGO1 Recombinant Antibody; Fab Fragment (HPAB-1292-FY-F(E)) | WB, ELISA | Human Fab |
| HPAB-1576-FY-F(E) | Human Anti-LINGO1 Recombinant Antibody; Fab Fragment (HPAB-1576-FY-F(E)) | WB, ELISA, IF | Human Fab |
| HPAB-1577-FY-F(E) | Human Anti-LINGO1 Recombinant Antibody; Fab Fragment (HPAB-1577-FY-F(E)) | WB, ELISA, IF | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0681CL | Anti-Human LINGO1 Recombinant Antibody (4784) | ELISA, FC | Human antibody |
| TAB-0682CL | Anti-Human LINGO1 Recombinant Antibody (4785) | ELISA, FC | Human antibody |
| TAB-0681CL-S(P) | Anti-Human LINGO1 Recombinant Antibody scFv Fragment (4784) | ELISA, FC | Human antibody |
| TAB-0682CL-S(P) | Anti-Human LINGO1 Recombinant Antibody scFv Fragment (4785) | ELISA, FC | Human antibody |
| TAB-0681CL-F(E) | Anti-Human LINGO1 Recombinant Antibody Fab Fragment (4784) | ELISA, FC | Human antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-1292-FY | Human Anti-LINGO1 Recombinant Antibody (HPAB-1292-FY) | WB, ELISA | Human IgG |
| HPAB-1576-FY | Human Anti-LINGO1 Recombinant Antibody (HPAB-1576-FY) | WB, ELISA, IF | Human IgG |
| HPAB-1577-FY | Human Anti-LINGO1 Recombinant Antibody (HPAB-1577-FY) | WB, ELISA, IF | Human IgG |
| HPAB-1578-FY | Human Anti-LINGO1 Recombinant Antibody (HPAB-1578-FY) | WB, ELISA, IF | Human IgG |
| VS-0323-XY17 | Human Anti-LINGO1 Recombinant Antibody (VS-0323-XY17) | ELISA | Human IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-FY142 | Human Anti-LINGO1 (clone 4784) scFv-Fc Chimera | ELISA, FC | Human IgG1, scFv-Fc |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-YC311 | Recombinant Anti-LINGO1 Vesicular Antibody, EV Displayed (VS-0425-YC311) | ELISA, FC, Cell-uptake |
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