Recombinant Mouse Anti-LRP1 Antibody (8G1)
CAT#: NEUT-1701CQ
This antibody is a mouse monoclonal antibody that binds specifically to Low Density LRP, and it can neutralize the bioactivity of Low Density LRP.
Gene Expression
Subcellular Location and Protein Expression
Figure 1 IF staining of human cell line RH-30
Immunofluorescent staining of human cell line RH-30 shows localization to nucleoplasm & vesicles.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/4182/1150_F4_7_selected.jpg
Subcellular Location and Protein Expression
Figure 2 IHC staining of human placenta
Immunohistochemical staining of human placenta shows moderate membranous positivity in trophoblastic cells.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/4182/13067_A_2_7_selected.jpg
Normal Tissue
Figure 3 Cerebral cortex
Neuronal cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/18621/41781_B_9_5.jpg
Normal Tissue
Figure 4 Colon
Fibroblasts
Staining: High
Intensity: Strong
Mucosal lymphoid cells
Staining: Medium
Intensity: Strong
Quantity: <25%
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/18621/41781_A_9_3.jpg
Normal Tissue
Figure 5 Liver
Hepatocytes
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/18621/41781_A_9_4.jpg
Normal Tissue
Figure 6 Kidney
Cells in tubules
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/22903/51316_A_9_5.jpg
Normal Tissue
Figure 7 Testis
Leydig cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/18621/41781_A_4_6.jpg
Normal Tissue
Figure 8 Soft tissue
Fibroblasts
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/18621/41781_B_2_8.jpg
Normal Tissue
Figure 9 Lymph node
Non-germinal center cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/18621/41781_A_9_8.jpg
RNA Expression
Figure 10 RNA cell line category: Cell line enhanced (ASC diff, ASC TERT1, fHDF/TERT166, HSkMC, hTERT-RPE1)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000123384-LRP1
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Specifications
- Immunogen
- Human LRP/alpha2 MR.
- Host Species
- Mouse
- Type
- IgG1, κ
- Specificity
- Specifically reacts with the 515kDa alpha chain of LRP/alpha2 MR
- Species Reactivity
- Human
- Clone
- 8G1
- Applications
- Used for immunoassay techniques such as: Blocking; Flow Cytometry; Immunocytochemistry/Immunofluorescence; Immunohistochemistry-Frozen; Immunohistochemistry-Paraffin; Western Blot
- Conjugate
- Unconjugated
Product Property
- Purification
- Protein A purified
- Purity
- >95% as determined by analysis by SDS-PAGE
- Storage
- Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze-thaw cycles.
Target
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Downloadable Resources
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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Protocol & Troubleshooting
We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.
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| CAT | Product Name | Application | Type |
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| MOB-631-F(E) | Recombinant Anti-human LRP1 Antibody Fab Fragment | IF, Neut, FuncS | Fab |
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| CAT | Product Name | Application | Type |
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| MOB-631-S(P) | Recombinant Anti-human LRP1 Antibody scFv Fragment | FC, IP, FuncS | scFv |
| MHH-631-S(P) | Recombinant Human Anti-human LRP1 Antibody scFv Fragment | FC, Neut, Funcs | scFv |
| HPAB-N0364-YC-S(P) | Human Anti-LRP1 Recombinant Antibody; scFv Fragment (HPAB-N0364-YC-S(P)) | WB, FuncS | Human scFv |
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| CAT | Product Name | Application | Type |
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| VS-0525-XY4092 | Anti-LRP1 Immunohistochemistry Kit | IHC | |
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| VS-0525-XY4094 | Anti-Mouse LRP1 Immunohistochemistry Kit | IHC |
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