Afuco™ Anti-Human MAP3K14 ADCC Recombinant Antibody, ADCC Enhanced (CAT#: AFC-492CL)
Anti-MAP3K14 ADCC Enhanced Antibody is an ADCC enhanced antibody produced by our Afuco™ platform. This is an antibody capable of specifically binding the amino acid sequence of NF-&kgr B-inducing kinase (NIK) MAP3K14, used for treatment including malignant diseases and diseases associated with pathological immune responses, such as autoimmune, allergic, inflammatory, and transplantation-related diseases.
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Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line U-2 OS
(Immunofluorescent staining of human cell line U-2 OS shows localization to nucleoplasm, nucleoli fibrillar center, cytosol & vesicles.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/27270/254_H10_1_selected.jpg
(Immunofluorescent staining of human cell line U-2 OS shows localization to nucleoplasm, nucleoli fibrillar center, cytosol & vesicles.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/27270/254_H10_1_selected.jpg
Figure 2 IHC staining of human small intestine
(Immunohistochemical staining of human small intestine shows moderate cytoplasmic positivity in glandular cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/27269/62044_A_5_2_selected.jpg
(Immunohistochemical staining of human small intestine shows moderate cytoplasmic positivity in glandular cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/27269/62044_A_5_2_selected.jpg
Figure 3 Cerebral cortex
(Neuronal cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Neuropil Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/27269/62044_B_8_5.jpg
(Neuronal cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Neuropil Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/27269/62044_B_8_5.jpg
Figure 4 Colon
(Endothelial cells Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous Glandular cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Peripheral nerve/ganglion Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/27269/62044_A_8_3.jpg
(Endothelial cells Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous Glandular cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Peripheral nerve/ganglion Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/27269/62044_A_8_3.jpg
Figure 5 Kidney
(Cells in tubules Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/27269/62044_A_7_5.jpg
(Cells in tubules Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/27269/62044_A_7_5.jpg
Figure 6 Testis
(Elongated or late spermatids Staining: Medium Intensity: Moderate Quantity: 75%-25% Leydig cells Staining: Low Intensity: Weak Quantity: 75%-25% Pachytene spermatocytes Staining: Low Intensity: Moderate Quantity: <25% Preleptotene spermatocytes Staining: Low Intensity: Moderate Quantity: <25% Round or early spermatids Staining: Medium Intensity: Moderate Quantity: 75%-25% Sertoli cells Staining: Medium Intensity: Moderate Quantity:>75% Spermatogonia cells Staining: Medium Intensity: Strong)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/27269/62044_A_4_6.jpg
(Elongated or late spermatids Staining: Medium Intensity: Moderate Quantity: 75%-25% Leydig cells Staining: Low Intensity: Weak Quantity: 75%-25% Pachytene spermatocytes Staining: Low Intensity: Moderate Quantity: <25% Preleptotene spermatocytes Staining: Low Intensity: Moderate Quantity: <25% Round or early spermatids Staining: Medium Intensity: Moderate Quantity: 75%-25% Sertoli cells Staining: Medium Intensity: Moderate Quantity:>75% Spermatogonia cells Staining: Medium Intensity: Strong)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/27269/62044_A_4_6.jpg
Figure 7 Lymph node
(Germinal center cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Non-germinal center cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/27269/62044_A_9_8.jpg
(Germinal center cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Non-germinal center cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/27269/62044_A_9_8.jpg
Figure 8 RNA cell line category: Cell line enhanced (A549, U-251 MG)
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000006062-MAP3K14
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000006062-MAP3K14
Specifications
- Host Species
- Human
- Type
- ADCC enhanced antibody
- Species Reactivity
- Human
- Related Disease
- Autoimmune Diseases
Product Property
- Purity
- Purity>95% by SDS-PAGE
- Storage
- 4 °C, -20°C if preferred
Target
- Alternative Names
- MAP3K14; mitogen-activated protein kinase kinase kinase 14; HS; NIK; HSNIK; FTDCR1B; NF-kappa-beta-inducing kinase; serine/threonine-protein kinase NIK
- Gene ID
- 9020
- UniProt ID
- Q68D39
Related Resources
Endometrial Cancer
Throid Cancer
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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See other products for "MAP3K14"
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Mouse Antibody Products
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IgG Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0836CL | Anti-Human MAP3K14 Recombinant Antibody (NIK-81) | ELISA, IP, WB | |
| TAB-0836CL-S(P) | Anti-Human MAP3K14 Recombinant Antibody scFv Fragment (NIK-81) | ELISA, IP, WB | |
| TAB-0836CL-F(E) | Anti-Human MAP3K14 Recombinant Antibody Fab Fragment (NIK-81) | ELISA, IP, WB |
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