Afuco™ Anti-Human MICB ADCC Recombinant Antibody, ADCC Enhanced (CAT#: AFC-506CL)
Anti-MICB ADCC Enhanced Antibody is an ADCC enhanced antibody produced by our Afuco™ platform. The antibodies which bind to MIC and inhibit MIC shedding are used for the treatment of cancer. In humans, the MHC class I chain-related molecule A (MICA) and MICB (generally termed as MIC) are the most investigated NKG2D ligands, which were proposed to play roles in tumor rejection.
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Subcellular Location
RNA Expression
Figure 1 IF staining of human cell line BJ
(Immunofluorescent staining of human cell line BJ shows localization to nucleoplasm, plasma membrane & the Golgi apparatus.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/64618/1446_E9_5_selected.jpg
(Immunofluorescent staining of human cell line BJ shows localization to nucleoplasm, plasma membrane & the Golgi apparatus.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/64618/1446_E9_5_selected.jpg
Figure 2 RNA cell line category: Cell line enhanced (U-266/70, U-266/84)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000204516-MICB
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000204516-MICB
Specifications
- Host Species
- Humanized
- Derivation
- Humanized
- Type
- ADCC enhanced antibody
- Species Reactivity
- Human
- Related Disease
- Cancer
Product Property
- Purity
- Purity>95% by SDS-PAGE
- Storage
- Store it under sterile conditions at -20°C upon receiving. Recommend to pack the protein into smaller quantities for optimal storage.
Target
- Alternative Names
- MICB; MHC class I polypeptide-related sequence B; PERB11.2; MHC class I mic-B antigen; stress inducible class I homolog; MHC class I chain-related protein B; MHC class I-like molecule PERB11.2-IMX
- Gene ID
- 4277
- UniProt ID
- B4DUT9
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
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Extracellular Vesicle (EV) Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-3208z | Mouse Anti-MICB Recombinant Antibody (clone 25D2) | WB, IP, IF, ELISA | Mouse IgG1, κ |
| MOB-1235CT | Recombinant Mouse anti-Human MICB Monoclonal antibody (NN0584-4D48) | FC, WB | |
| HPAB-N0178-YC | Mouse Anti-MICB Recombinant Antibody (HPAB-N0178-YC) | ELISA, FC | Mouse IgG2 |
| VS-0723-WK236 | Rabbit Anti-MICB Recombinant Antibody (VS-0723-WK236) | ELISA, FC | Rabbit IgG |
| VS7-0425-WR384 | Mouse Anti-MICB Recombinant Antibody (clone 1B2F11) | FC | Mouse IgG1 |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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