Anti-Human MMP13 Recombinant Antibody (14D10) (CAT#: TAB-0819CL)
Recombinant monoclonal antibody 14D10 is a mouse monoclonal antibody that specifically binds to human MMP-13. The isotype of 14D10 is IgG2a.
Specific Inquiry
ELISA
Figure 1 Binding characteristics of the MMP-13-neutralizing antibody 14D10.
Binding of 14D10 to various MMPs was evaluated using a competitive inhibition ELISA.
Naito, S., Takahashi, T., Onoda, J., Yamauchi, A., Kawai, T., Kishino, J., ... & Numata, Y. (2012). Development of a neutralizing antibody specific for the active form of matrix metalloproteinase-13. Biochemistry, 51(44), 8877-8884.
Inhib
Figure 2 Inhibition of the collagenolytic activity of human chondrocyte culture by 14D10.
Human articular chondrocytes were cultured as a monolayer on a plate coated with native type II collagen and stimulated by IL-1β and Oncostatin M to release collagenases, in the presence of the indicated concentrations of 14D10 or control IgG2b.
Naito, S., Takahashi, T., Onoda, J., Yamauchi, A., Kawai, T., Kishino, J., ... & Numata, Y. (2012). Development of a neutralizing antibody specific for the active form of matrix metalloproteinase-13. Biochemistry, 51(44), 8877-8884.
Specifications
- Immunogen
- MMP13 partial peptide(225-246)-KLH complex.
- Host Species
- Mouse
- Specificity
- Human
- Clone
- 14D10
- Applications
- Inhib, ELISA
- Related Disease
- Osteoarthritis
Applications
- Application Notes
- ELISA: 1/10000
Target
- Alternative Names
- MMP13; matrix metallopeptidase 13 (collagenase 3); CLG3; MANDP1; MMP-13; collagenase 3; matrix metalloproteinase 13 (collagenase 3)
- Gene ID
- 4322
- UniProt ID
- P45452
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2081z | Mouse Anti-MMP13 Recombinant Antibody (clone 19A7) | WB, ICC, IF, IHC | Mouse IgG2a |
| MOB-1941MZ | Recombinant Mouse Anti-Rat MMP13 Antibody (clone MJQDP JJE2), Biotin-Conjugated | ICC/IF, IP, WB | Mouse antibody |
| MRO-1009-CN | Recombinant Rabbit Anti-MMP13 Monoclonal Antibody (JF0893) | WB, IF, IHC, FC | Rabbit IgG |
| VS3-WK1856 | Recombinant Rabbit Anti-MMP13 Capture Antibody (clone R73-2Z-9) | ELISA | Rabbit IgG |
| VS3-WK1857 | Recombinant Rabbit Anti-MMP13 Detection Antibody (clone R78-6T-5) | ELISA | Rabbit IgG |
Human Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0820CL | Human Anti-MMP13 Recombinant Antibody (TAB-0820CL) | ELISA, IHC | Human IgG |
| TAB-0821CL | Human Anti-MMP13 Recombinant Antibody (TAB-0821CL) | ELISA, IHC | Human IgG |
| TAB-0820CL-S(P) | Human Anti-MMP13 Recombinant Antibody; scFv Fragment (TAB-0820CL-S(P)) | ELISA, IHC | Human scFv |
| TAB-0821CL-S(P) | Human Anti-MMP13 Recombinant Antibody; scFv Fragment (TAB-0821CL-S(P)) | ELISA, IHC | Human scFv |
| TAB-0820CL-F(E) | Human Anti-MMP13 Recombinant Antibody; Fab Fragment (TAB-0820CL-F(E)) | ELISA, IHC | Human Fab |
Mouse Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0819CL-S(P) | Anti-Human MMP13 Recombinant Antibody scFv Fragment (14D10) | ELISA | |
| TAB-0819CL-F(E) | Anti-Human MMP13 Recombinant Antibody Fab Fragment (14D10) | ELISA |
Chicken IgY Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| BRD-0369MZ | Chicken Anti-MMP13 Polyclonal IgY | WB | Chicken antibody |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-2250 | Hi-Affi™ Recombinant Rabbit Anti-MMP13 Monoclonal Antibody (DS2250AB) | WB | IgG |
| MOR-4649 | Hi-Affi™ Recombinant Rabbit Anti-MMP13 Monoclonal Antibody (TH162DS) | WB, IF, ICC, IHC-P, FC | IgG |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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