Recombinant Anti-human PABPN1 Intrabody [(D-Arg)9]

CAT#: IAB-B060(A)

Recombinant anti-PABPN1 intrabody linked to (D-Arg)9 works within cells to bind human PABPN1, expressed in E. coli cells.

Gene Expression
Figure 1 IF staining of human cell line U-251 MG Figure 2 Cerebral cortex Figure 3 Colon Figure 4 Liver Figure 5 Pancreas Figure 6 Kidney Figure 7 Testis Figure 8 Lymph node Figure 9 RNA cell line category: Low cell line specificity

Specifications

  • Immunogen
  • human poly(A) binding protein, nuclear 1
  • Host Species
  • llama
  • Type
  • vhh-(D-Arg)9
  • Cell Penetrating Peptide
  • (D-Arg)9
    It has been proven that polyarginine peptides composed of nine arginine amino acids (Arg-9) are able to translocate across cells very efficiently. This raises the question if molecular dynamics simulations would show a similar pathway for this highly hydrophilic and charged peptide as predicted for the Tat peptide. The simplicity of Arg-9 over other CPPs also helps isolate the role of the Arg sidechain on the translocation without the effect of other sidechains. Therefore, in this work we study computationally the translocation of Arg-9 through a lipid bilayer and show that the translocation mechanism is the same as for the Tat peptide.
  • Species Reactivity
  • human
  • Applications
  • Antibody assay: Fluorescence-activated cell sorting; Immunocytochemistry; Functional studies

Product Property

  • Purity
  • >95% as determined by Analysis by RP-HPLC & analysis by SDS-PAGE
  • Storage
  • 4 °C, -20°C if preferred

Target

  • Alternative Names
  • PABPN1; poly(A) binding protein, nuclear 1; OPMD; PAB2; PABII; PABP2; PABP-2; polyadenylate-binding protein 2; poly(A) binding protein 2; poly(A) binding protein II
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Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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