Anti-Human PLAUR Recombinant Antibody Fab Fragment (2.6.1) (CAT#: TAB-237CQ-F(E))
The human monoclonal antibody binds to the uPAR with high affinity (KD=249 pM) and can inhibit uPAR-induced cell adhesion and invasion.
Specific Inquiry
Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line U-2 OS
(Immunofluorescent staining of human cell line U-2 OS shows localization to plasma membrane.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/73533/if_selected.jpg
(Immunofluorescent staining of human cell line U-2 OS shows localization to plasma membrane.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/73533/if_selected.jpg
Figure 2 IHC staining of human bone marrow
(Immunohistochemical staining of human bone marrow shows strong cytoplasmic positivity in megakaryocytes.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/50843/ihc_selected.jpg
(Immunohistochemical staining of human bone marrow shows strong cytoplasmic positivity in megakaryocytes.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/50843/ihc_selected.jpg
Figure 3 Cerebral cortex
(Neuropil
Staining:
Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/
membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/50843/117396_B_7_5.jpg
(Neuropil
Staining:
Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/
membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/50843/117396_B_7_5.jpg
Figure 4 Colon
(Peripheral nerve/ganglion
Staining:
Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/
membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/50843/117396_A_9_3.jpg
(Peripheral nerve/ganglion
Staining:
Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/
membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/50843/117396_A_9_3.jpg
Figure 5 Kidney
(Cells in tubules
Staining:
Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/
membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/50843/117396_A_8_5.jpg
(Cells in tubules
Staining:
Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/
membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/50843/117396_A_8_5.jpg
Figure 6 Testis
(Cells in seminiferous ducts
Staining:
Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/
membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/50843/117396_A_5_6.jpg
(Cells in seminiferous ducts
Staining:
Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/
membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/50843/117396_A_5_6.jpg
Figure 7 Bone marrow
(Hematopoietic cells
Staining:
Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/
membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/50843/117396_B_5_4.jpg
(Hematopoietic cells
Staining:
Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/
membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/50843/117396_B_5_4.jpg
Figure 8 RNA cell line category: Cell line enhanced.
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000011422-PLAUR
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000011422-PLAUR
Figure 8 RNA cell line category: Cell line enhanced.
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000011422-PLAUR
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000011422-PLAUR
Specifications
- Immunogen
- Soluble uPAR and cell-bound uPAR
- Host Species
- Human
- Type
- Human antibody
- Specificity
- Human
- Species Reactivity
- Human, Cynomolgous monkey
- Clone
- 2.6.1
- Applications
- Used for immunoassay techniques such as: Enzyme-linked Immunosorbent Assay; Flow Cytometry; Western Blot
- Related Disease
- Cell adhesion and invasion
Target
- Alternative Names
- PLAUR; Plasminogen activator, urokinase receptor; Urokinase receptor; uPA receptor; uPAR; CD87; Cluster of Differentiation 87; Urokinase Plasminogen Activator Receptor; UPAR; URKR; U-PAR
- Gene ID
- 5329
- UniProt ID
- Q03405
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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|---|---|---|---|
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| MOB-0021MZ | Recombinant Mouse Anti-Mouse Plaur Antibody (clone C042M) | ELISA | Mouse antibody |
| HPAB-0175-YC | Mouse Anti-PLAUR Recombinant Antibody (clone 7G1) | ELISA, WB | Mouse IgG |
| HPAB-0616YY | Human Anti-PLAUR Recombinant Antibody (clone H5L5) | ELISA, FC, WB | Humanized IgG |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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