Recombinant Anti-PREV Intrabody [(D-Arg)9] (CAT#: IAB-B007(A))
Recombinant anti-PREV intrabody linked to (D-Arg)9 works within cells to bind secifically to a retrovirus protein PREV particle protein, expressed in 293T cells. Intracellular antibody which disrupts the catalysis of the production of the xenoantigen galactose α 1,3 galactose and/or a polynucleotide construct which encodes an intracellular antibody which binds specifically to a retrovirus protein, such as a PERV particle protein.
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Specifications
- Immunogen
- porcine retroviruses
- Host Species
- llama
- Type
- vhh-(D-Arg)9
- Cell Penetrating Peptide
- (D-Arg)9
It has been proven that polyarginine peptides composed of nine arginine amino acids (Arg-9) are able to translocate across cells very efficiently. This raises the question if molecular dynamics simulations would show a similar pathway for this highly hydrophilic and charged peptide as predicted for the Tat peptide. The simplicity of Arg-9 over other CPPs also helps isolate the role of the Arg sidechain on the translocation without the effect of other sidechains. Therefore, in this work we study computationally the translocation of Arg-9 through a lipid bilayer and show that the translocation mechanism is the same as for the Tat peptide.
- Species Reactivity
- PERV
- Applications
- Used for immunoassay techniques such as: Fluorescence-activated cell sorting; Immunocytochemistry; Functional studies
Product Property
- Purity
- Purity>95% by SDS-PAGE
- Storage
- 4 °C, -20°C if preferred
Target
- Alternative Names
- PREV; porcine retroviruses
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
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Intrabody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| IAB-B007(G) | Recombinant Anti-PREV Intrabody [+36 GFP] | ELISA, ICC, FuncS | vhh-(+36GFP) |
| IAB-B007(T) | Recombinant Anti-PREV Intrabody [Tat] | PCA, Neut, FuncS | vhh-Tat |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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