Recombinant Anti-PrPC Intrabody [(D-Arg)9] (CAT#: IAB-B055(A))
Recombinant anti-PrPC intrabody linked to (D-Arg)9 works within cells and specifically reacts with endogenous PrPC, expressed in E. coli cells.
Specific Inquiry
Specifications
- Immunogen
- prion protein
- Host Species
- human
- Type
- scFv-(D-Arg)9
- Cell Penetrating Peptide
- (D-Arg)9
It has been proven that polyarginine peptides composed of nine arginine amino acids (Arg-9) are able to translocate across cells very efficiently. This raises the question if molecular dynamics simulations would show a similar pathway for this highly hydrophilic and charged peptide as predicted for the Tat peptide. The simplicity of Arg-9 over other CPPs also helps isolate the role of the Arg sidechain on the translocation without the effect of other sidechains. Therefore, in this work we study computationally the translocation of Arg-9 through a lipid bilayer and show that the translocation mechanism is the same as for the Tat peptide.
- Species Reactivity
- human
- Applications
- Antibody assay: Immunofluorescence; Enzyme-linked Immunosorbent Assay; Functional studies
Product Property
- Purity
- >95%, by SDS-PAGE with Coomassie Brilliant Blue staining
- Storage
- Store the antibody (in aliquots) at -20°C. Avoid repeated freezing and thawing of samples.
Target
- Alternative Names
- PrPC; prion protein
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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See other products for "PrPC"
Intrabody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| IAB-B055(G) | Recombinant Anti-PrPC Intrabody [+36 GFP] | FC, IF, FuncS | scFv-(+36GFP) |
| IAB-B055(T) | Recombinant Anti-PrPC Intrabody [Tat] | CO-IP, FuncS | scFv-Tat |
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0322-YJ | Mouse Anti-PrPc Recombinant Antibody (HPAB-0322-YJ) | ELISA, WB, IF, Inhib, FuncS | Mouse IgG |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0322-YJ-S(P) | Mouse Anti-PrPc Recombinant Antibody; scFv Fragment (HPAB-0322-YJ-S(P)) | ELISA, WB, IF, Inhib, FuncS | Mouse scFv |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0322-YJ-F(E) | Mouse Anti-PrPc Recombinant Antibody; Fab Fragment (HPAB-0322-YJ-F(E)) | ELISA, WB, IF, Inhib, FuncS | Mouse Fab |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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