Human Anti-ROBO4 Recombinant Antibody (clone YW71.22)
CAT#: NS-076CN
The anti-ROBO4 antibody specifically binds to ROBO4. ROBO4 relates generally to the fields of angiogenesis, and endothelial cell proliferation and migration. Thus, this antibody can be used to treatment studies of diseases and disorders associated angiogenesis, such as cancer, atherosclerosis, and so on.
Published Data
Gene Expression
Figure 1 The results of endothelial cell migration assay. Anti-Robo4 antibody did not block VEGF induced EC migration.
Figure 2 Changes in median tumor volume as a function of time in xenograft mouse models dosed with control, anti-VEGF, anti-Robo4 (YW71.22), and anti-Robo4 plus anti-VEGF antibodies.
Naked Robo4 antibody did not inhibit tumor growth in these experiments.
FuncS
Figure 3 anti-Robo4 antibody 71.22 associates with vasculature following injection into mice.
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Subcellular Location
Figure 1 IF staining of human cell line PC-3
Immunofluorescent staining of human cell line PC-3 shows localization to plasma membrane.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/65212/1589_F7_2_selected.jpg
RNA Expression
Figure 2 RNA cell line category: Group enriched (HUVEC TERT2, TIME)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000154133-ROBO4
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Specifications
- Immunogen
- His-tagged human ROBO4
- Host Species
- Human
- Derivation
- Phage display library
- Type
- Human IgG
- Specificity
- Human
- Species Reactivity
- Human, Mouse
- Clone
- YW71.22
- Applications
- FC, ELISA, FuncS
- Related Disease
- Angiogenesis disorder
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- This antibody has been tested for use in Functional Assay.
Target
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "Clone YW71.22"
- CAT
- Product Name
See other products for "ROBO4"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-329CT | Mouse Anti-Robo4 Recombinant Antibody (TAB-329CT) | WB, ELISA, FC, IHC | Mouse IgG2a |
| TAB-329CT-S(P) | Mouse Anti-Robo4 Recombinant Antibody; scFv Fragment (TAB-329CT-S(P)) | WB, ELISA, FC, IHC | Mouse scFv |
| TAB-329CT-F(E) | Mouse Anti-Robo4 Recombinant Antibody; Fab Fragment (TAB-329CT-F(E)) | WB, ELISA, FC, IHC | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-330CT | Anti-Human Robo4 Recombinant Antibody (YW79.11) | WB, ELISA, FC | Human antibody |
| TAB-330CT-S(P) | Anti-Human Robo4 Recombinant Antibody scFv Fragment (YW79.11) | WB, ELISA, FC | Human antibody |
| TAB-330CT-F(E) | Anti-Human Robo4 Recombinant Antibody Fab Fragment (YW79.11) | WB, ELISA, FC | Human antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-4396 | Hi-Affi™ Recombinant Rabbit Anti-ROBO4 Monoclonal Antibody (SI487DS) | ELISA | IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NS-076CN-F(E) | Human Anti-ROBO4 Recombinant Antibody (clone YW71.22); Fab Fragment | FC, ELISA | Human Fab |
| NS-076CN-S(P) | Human Anti-ROBO4 Recombinant Antibody (clone YW71.22); scFv Fragment | FC, ELISA | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0045-WJ-S(P) | Human Anti-ROBO4 Recombinant Antibody; scFv Fragment (HPAB-0045-WJ-S(P)) | ELISA, RIA | Humanized scFv |
| HPAB-AP412-YC-S(P) | Human Anti-ROBO4 Recombinant Antibody (clone cMAb1-1); scFv Fragment | ELISA, FC | Mouse scFv |
| HPAB-AP413-YC-S(P) | Human Anti-ROBO4 Recombinant Antibody (clone cMAb1-2); scFv Fragment | ELISA, FC | Mouse scFv |
| HPAB-J0217-YC-S(P) | Human Anti-ROBO4 Recombinant Antibody (clone YW71.6); scFv Fragment | ELISA | Human scFv |
| HPAB-J0218-YC-S(P) | Human Anti-ROBO4 Recombinant Antibody (clone YW71.1); scFv Fragment | ELISA | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0045-WJ-F(E) | Human Anti-ROBO4 Recombinant Antibody; Fab Fragment (HPAB-0045-WJ-F(E)) | ELISA, RIA | Humanized Fab |
| HPAB-AP412-YC-F(E) | Human Anti-ROBO4 Recombinant Antibody (clone cMAb1-1); Fab Fragment | ELISA, FC | Chimeric (mouse/human) Fab |
| HPAB-AP413-YC-F(E) | Human Anti-ROBO4 Recombinant Antibody (clone cMAb1-2); Fab Fragment | ELISA, FC | Chimeric (mouse/human) Fab |
| HPAB-J0217-YC-F(E) | Human Anti-ROBO4 Recombinant Antibody (clone YW71.6); Fab Fragment | ELISA | Human Fab |
| HPAB-J0218-YC-F(E) | Human Anti-ROBO4 Recombinant Antibody (clone YW71.1); Fab Fragment | ELISA | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-J0217-YC | Human Anti-ROBO4 Recombinant Antibody (clone YW71.6) | ELISA | Human IgG |
| HPAB-J0218-YC | Human Anti-ROBO4 Recombinant Antibody (clone YW71.1) | ELISA | Human IgG |
| HPAB-J0219-YC | Human Anti-ROBO4 Recombinant Antibody (clone YW79.1) | ELISA | Human IgG |
| HPAB-J0220-YC | Human Anti-ROBO4 Recombinant Antibody (clone YW79.8) | ELISA | Human IgG |
| HPAB-J0221-YC | Human Anti-ROBO4 Recombinant Antibody (clone YW71.22.S1.16) | ELISA, FC | Human IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-YC496 | Recombinant Anti-ROBO4 Vesicular Antibody, EV Displayed (VS-0425-YC496) | ELISA, FC, Cell-uptake |
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