Human Anti-ROBO4 Recombinant Antibody (clone YW71.22) (CAT#: NS-076CN)
The anti-ROBO4 antibody specifically binds to ROBO4. ROBO4 relates generally to the fields of angiogenesis, and endothelial cell proliferation and migration. Thus, this antibody can be used to treatment studies of diseases and disorders associated angiogenesis, such as cancer, atherosclerosis, and so on.
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We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
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Figure 1 The results of endothelial cell migration assay. Anti-Robo4 antibody did not block VEGF induced EC migration.
Figure 2 Changes in median tumor volume as a function of time in xenograft mouse models dosed with control, anti-VEGF, anti-Robo4 (YW71.22), and anti-Robo4 plus anti-VEGF antibodies.
Naked Robo4 antibody did not inhibit tumor growth in these experiments.
FuncS
Figure 3 anti-Robo4 antibody 71.22 associates with vasculature following injection into mice.
Specifications
- Immunogen
- His-tagged human ROBO4
- Host Species
- Human
- Derivation
- Phage display library
- Type
- Human IgG
- Specificity
- Human
- Species Reactivity
- Human, Mouse
- Clone
- YW71.22
- Applications
- FC, ELISA, FuncS
- Related Disease
- Angiogenesis disorder
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- This antibody has been tested for use in Functional Assay.
Target
- Alternative Names
- ROBO4; roundabout, axon guidance receptor, homolog 4 (Drosophila); MRB; ECSM4; roundabout homolog 4; roundabout homolog 4, magic roundabout
- Gene ID
- 54538
- UniProt ID
- B4DYV8
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
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Extracellular Vesicle (EV) Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-329CT | Mouse Anti-Robo4 Recombinant Antibody (TAB-329CT) | WB, ELISA, FC, IHC | Mouse IgG2a |
| TAB-329CT-S(P) | Mouse Anti-Robo4 Recombinant Antibody; scFv Fragment (TAB-329CT-S(P)) | WB, ELISA, FC, IHC | Mouse scFv |
| TAB-329CT-F(E) | Mouse Anti-Robo4 Recombinant Antibody; Fab Fragment (TAB-329CT-F(E)) | WB, ELISA, FC, IHC | Mouse Fab |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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