Human Anti-ROBO4 Recombinant Antibody (clone cMAb1-2); Fab Fragment (CAT#: HPAB-AP413-YC-F(E))
Provided is an anti-ROBO4 antibody that activates the downstream signal of ROBO4 and has suppressive activity against cell migration induced by VEGF or bFGF. The antibody also exhibits an anti-angiogenesis effect in in-vivo models.
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Custom Production
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
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Subcellular Location
RNA Expression
Figure 1 IF staining of human cell line PC-3
(Immunofluorescent staining of human cell line PC-3 shows localization to plasma membrane.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/65212/1589_F7_2_selected.jpg
(Immunofluorescent staining of human cell line PC-3 shows localization to plasma membrane.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/65212/1589_F7_2_selected.jpg
Figure 2 RNA cell line category: Group enriched (HUVEC TERT2, TIME)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000154133-ROBO4
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000154133-ROBO4
Specifications
- Immunogen
- rROBO4-ECD
- Host Species
- Human
- Derivation
- Chimeric (mouse/human)
- Type
- Chimeric (mouse/human) Fab
- Specificity
- Human ROBO4
- Species Reactivity
- Human
- Clone
- cMAb1-2
- Applications
- ELISA, FC
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- Roundabout Guidance Receptor 4; Magic Roundabout; Roundabout, Axon Guidance Receptor, Homolog 4 (Drosophila); Roundabout, Axon Guidance Receptor, Homolog 4; Roundabout Homolog 4, Magic Roundabout; Roundabout Homolog 4 (Drosophila); Roundabout Homolog 4; ECSM4; MRB
- Gene ID
- 54538
- UniProt ID
- Q8WZ75
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Mouse Antibodies
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Fab Antibodies
ScFv Antibodies
Extracellular Vesicle Antibodies
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-329CT | Mouse Anti-Robo4 Recombinant Antibody (TAB-329CT) | WB, ELISA, FC, IHC | Mouse IgG2a |
| TAB-329CT-S(P) | Mouse Anti-Robo4 Recombinant Antibody; scFv Fragment (TAB-329CT-S(P)) | WB, ELISA, FC, IHC | Mouse scFv |
| TAB-329CT-F(E) | Mouse Anti-Robo4 Recombinant Antibody; Fab Fragment (TAB-329CT-F(E)) | WB, ELISA, FC, IHC | Mouse Fab |
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