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Anti-Human SSB Recombinant Antibody (CAT#: TAB-583CL)

Recombinant Humanized monoclonal antibody expressed in CHO binding to Human SSB. The antibodiess against the human La protein can be used in immuno targeting, in particular the immuno targeting of tumour cells.

Specific Inquiry
  • Size:
  • Conjugation:
  • Endotoxin:
  • Purity:
  • Formats:
  • Isotype Switching:
  • Fc Engineering:
  • Modalities:
  • Gene Expression
  • Datasheet
  • MSDS
  • COA
Subcellular Location
Figure 1 IF staining of human cell line U-251 MG
Figure 1 IF staining of human cell line U-251 MG
(Immunofluorescent staining of human cell line U-251 MG shows localization to nucleoplasm.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/17287/if_selected.jpg
Figure 2 IHC staining of human nasopharynx
Figure 2 IHC staining of human nasopharynx
(Immunohistochemical staining of human nasopharynx shows strong nuclear positivity in respiratory epithelial cells.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/17287/40060_B_8_2_selected.jpg
Normal Tissue
Figure 3 Cerebral cortex
Figure 3 Cerebral cortex
(Endothelial cells
Staining:

Medium

Intensity: Moderate
Quantity:>75%
Location: Nuclear
Glial cells
Staining:

Medium

Intensity: Moderate
Quantity:>75%
Location: Nuclear
Neuronal cells
Staining:

High

Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/
membranous
nuclear)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/4643/15243_B_8_5.jpg
Figure 4 Colon
Figure 4 Colon
(Glandular cells
Staining:

High

Intensity: Strong
Quantity:>75%
Location: Nuclear)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/4643/15243_A_8_3.jpg
Figure 5 Liver
Figure 5 Liver
(Cholangiocytes
Staining:

High

Intensity: Strong
Quantity:>75%
Location: Nuclear
Hepatocytes
Staining:

High

Intensity: Strong
Quantity: 75%-25%
Location: Nuclear)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/4643/15243_A_8_4.jpg
Figure 6 Pancreas
Figure 6 Pancreas
(Exocrine glandular cells
Staining:

High

Intensity: Strong
Quantity:>75%
Location: Nuclear
Pancreatic endocrine cells
Staining:

High

Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/
membranous
nuclear)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/4643/15243_A_2_3.jpg
Figure 7 Kidney
Figure 7 Kidney
(Cells in glomeruli
Staining:

High

Intensity: Strong
Quantity:>75%
Location: Nuclear
Cells in tubules
Staining:

High

Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/
membranous
nuclear)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/4643/15243_A_9_5.jpg
Figure 8 Testis
Figure 8 Testis
(Leydig cells
Staining:

High

Intensity: Strong
Quantity:>75%
Pachytene spermatocytes
Staining:

High

Intensity: Strong
Quantity:>75%
Peritubular cells
Staining:

Medium

Intensity: Moderate
Quantity: 75%-25%
Preleptotene spermatocytes
Staining:

High

Intensity: Strong
Quantity:>75%
Round or early spermatids
Staining:

High

Intensity: Strong
Quantity:>75%
Sertoli cells
Staining:

High

Intensity: Strong
Quantity:>75%
Spermatogonia cells
Staining:

High

Intensity: Strong
Quantity:>75%)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/4643/15243_A_5_6.jpg
Figure 9 Lymph node
Figure 9 Lymph node
(Germinal center cells
Staining:

Medium

Intensity: Moderate
Quantity:>75%
Location: Nuclear
Non-germinal center cells
Staining:

Medium

Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/
membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/4643/15243_A_8_8.jpg
RNA Expression
Figure 10 RNA cell line category: Low cell line specificity
Figure 10 RNA cell line category: Low cell line specificity
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000138385-SSB
Figure 10 RNA cell line category: Low cell line specificity
Figure 10 RNA cell line category: Low cell line specificity
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000138385-SSB

Specifications

  • Derivation
  • Humanized
  • Type
  • Antibody
  • Species Reactivity
  • Human
  • Related Disease
  • Cancer

Product Property

  • Purity
  • >95% (SDS-PAGE)
  • Storage
  • Short Term Storage: 4°C
    Long Term Storage: -20°C

Target

  • Alternative Names
  • SSB; Sjogren syndrome antigen B (autoantigen La); La; LARP3; La/SSB; lupus La protein; SS-B; autoantigen La; la autoantigen; SS-B/La protein; lupus La antigen; sjoegren syndrome type B antigen; La ribonucleoprotein domain family, member 3

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

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CAT Product Name Application Type
MOB-1194z Mouse Anti-SSB Recombinant Antibody (clone 9H2) WB, ICC, IF, IHC, IP Mouse IgG1
HPAB-0881-FY Mouse Anti-SSB Recombinant Antibody (HPAB-0881-FY) WB, IP, IF Mouse IgG2a
HPAB-0882-FY Mouse Anti-SSB Recombinant Antibody (HPAB-0882-FY) WB, IP, IF Mouse IgG1
HPAB-0883-FY Mouse Anti-SSB Recombinant Antibody (HPAB-0883-FY) WB, IP, IF Mouse IgG2b
VS3-QX1054 Mouse Anti-SSB Recombinant Antibody (clone 4B10-E11-H11) WB Mouse IgG1

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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