Anti-Human TNFRSF21 Recombinant Antibody (DQM3) (CAT#: TAB-631CL)
Recombinant Human monoclonal antibody expressed in CHO binding to Human TNFRSF21. DQM3 is a functional agonist monoclonal antibody against DR6, which bound to the first cysteine-rich domain. Death receptor 6 (DR6) is a member of the death domain-containing receptors that belong to the TNFR superfamily.
Specific Inquiry
Stim
Figure 1 DQM3 stimulates DR6-induced IL-6 luciferase activity.
HEK293T cells were co-transfected with DR6-FL, IL-6 luciferase reporter and Renilla. Anti-DR6 mAbs (DQM2, DQM3 and DQM5, 10 lg/ml) were added 24 h after transfection, and isotype control antibody alone also served as a negative control. Luciferase assays were performed to measure promoter activity after 16 h of antibody incubation.
Hu, R., Du, Q., Yin, X., Li, J., Wang, T., & Zhang, L. (2014). Agonist antibody activates death receptor 6 downstream signaling involving TRADD recruitment. FEBS letters, 588(3), 401-407.
Specifications
- Host Species
- Human
- Type
- Antibody
- Species Reactivity
- Human
- Applications
- Stim
- Related Disease
- Cancer
Product Property
- Purity
- >95%, by SDS-PAGE with Coomassie Brilliant Blue staining
- Storage
- Short term: store at 4°C (over 6 months), long term: -20°C or -80°C.
Applications
- Application Notes
- This antibody has been tested for use in Stimulation. It's recommended that the optimal antibody concentration, dilution, incubition time, etc. be carefully titrated in specific assays.
Target
- Alternative Names
- TNFRSF21; tumor necrosis factor receptor superfamily, member 21; DR6; CD358; BM-018; tumor necrosis factor receptor superfamily member 21; death receptor 6; TNFR-related death receptor 6
- Gene ID
- 27242
- UniProt ID
- A0A024RD71
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "TNFRSF21"
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-984 | Recombinant Anti-human TNFRSF21 Antibody | ELISA, WB, FuncS | IgG |
| MHH-984 | Recombinant Human Anti-human TNFRSF21 Antibody | IF, FC, FuncS | IgG |
| MOB-2092MZ | Recombinant Mouse Anti-Human TNFRSF21 Antibody (clone ES-7-05-FD) | FC, ICC/IF, IP | Mouse antibody |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-984-F(E) | Recombinant Anti-human TNFRSF21 Antibody Fab Fragment | RIA, IP, FuncS | Fab |
| MHH-984-F(E) | Recombinant Human Anti-human TNFRSF21 Antibody Fab Fragment | WB, IF, FuncS | Fab |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-984-S(P) | Recombinant Anti-human TNFRSF21 Antibody scFv Fragment | ELISA, IP, FuncS | scFv |
| MHH-984-S(P) | Recombinant Human Anti-human TNFRSF21 Antibody scFv Fragment | WB, Neut, FuncS | scFv |
Mouse Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-108CQ-S(P) | Mouse Anti-TNFRSF21 Recombinant Antibody; scFv Fragment (TAB-108CQ-S(P)) | ELISA, FC, IHC, WB, IP | Mouse scFv |
| TAB-108CQ-F(E) | Mouse Anti-TNFRSF21 Recombinant Antibody; Fab Fragment (TAB-108CQ-F(E)) | ELISA, FC, IHC, WB, IP | Mouse Fab |
Human Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-109CQ-S(P) | Human Anti-TNFRSF21 Recombinant Antibody; scFv Fragment (TAB-109CQ-S(P)) | ELISA, FC, IHC, WB, IP | Human scFv |
| TAB-109CQ-F(E) | Human Anti-TNFRSF21 Recombinant Antibody; Fab Fragment (TAB-109CQ-F(E)) | ELISA, FC, IHC, WB, IP | Human Fab |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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