Anti-Human TNFRSF4 Recombinant Antibody (12H3) (CAT#: TAB-0886CL)
This antibody specifically recognizes the extracellular domain of human CD134 and can be potentially used in cancer treatment.
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Figure 1 Binding characteristics of mouse anti-human CD134 antibodies clone ACT35, clone 12H3, and clone 20E5 on PHA-M-stimulated human CD134 expressing T lymphocytes.
Figure 2 Binding of mouse anti-human CD134 antibodies clone 12H3 and clone 20E5 on PHA-M-stimulated human CD134 expressing CD4 T lymphocytes and CD8 T lymphocytes.
FuncS
Figure 3 Dose effect of exposure to mouse anti-human CD134 antibodies clone 12H3 or clone 20E5, or to human OX40L on proliferation of PHA-M-stimulated human CD134 expressing T lymphocytes.
FuncS
Figure 4 Effect of combining mouse anti-human CD134 antibodies clone 12H3 with human OX40L, or mouse anti-human CD134 antibodies clone 20E5 with human OX40L on proliferation of PHA-M-stimulated human CD134 expressing T lymphocytes.
FuncS
Figure 5 Effect of exposure to mouse anti-human CD134 antibodies clone 12H3 or clone 20E5, or to human OX40L on proliferation of anti-human CD3/anti-human CD28 antibody stimulator beads-stimulated human CD134 expressing human regulatory T lymphocytes.
Specifications
- Immunogen
- Human CD134-transfected Sf9 insect cell lysates
- Host Species
- Mouse
- Specificity
- Human
- Clone
- 12H3
- Applications
- FuncS, FC
- Related Disease
- Cancers expressing CD134
Applications
- Application Notes
- The antibody was validated for Functional Assay, Flow Cytometry. For details, refer to Published Data.
Target
- Alternative Names
- TNFRSF4; tumor necrosis factor receptor superfamily, member 4; OX40; ACT35; CD134; IMD16; TXGP1L; tumor necrosis factor receptor superfamily member 4; OX40 antigen; ACT35 antigen; ATC35 antigen; CD134 antigen; OX40 homologue; OX40L receptor; OX40 cell surface antigen; lymphoid activation antigene ACT35; TAX transcriptionally-activated glycoprotein 1 receptor; tax-transcriptionally activated glycoprotein 1 receptor
- Gene ID
- 7293
- UniProt ID
- P43489
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
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Extracellular Vesicle (EV) Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0873CL | Human Anti-TNFRSF4 Recombinant Antibody (TAB-0873CL) | FC, Inhib | Humanized antibody |
| TAB-0876CL | Human Anti-TNFRSF4 Recombinant Antibody (TAB-0876CL) | ELISA, FuncS, FC | Humanized IgG |
| TAB-0880CL | Human Anti-TNFRSF4 Recombinant Antibody (TAB-0880CL) | FC | Humanized antibody |
| TAB-445CQ | Anti-Human TNFRSF4 Recombinant Antibody (Vonlerolizumab) | ELISA, IHC, FC, IP, IF, FuncS | IgG1, κ |
| TAB-452CQ | Anti-Human TNFRSF4 Recombinant Antibody (TAB-452CQ) | ELISA, IHC, FC, IP, IF, FuncS | IgG1, κ |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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