Anti-Human TNFRSF4 Recombinant Antibody (20E5)

CAT#: TAB-0887CL

This antibody specifically recognizes the extracellular domain of human CD134 and can be potentially used in cancer treatment.

Published Data Gene Expression
Figure 1 Binding characteristics of mouse anti-human CD134 antibodies clone ACT35, clone 12H3, and clone 20E5 on PHA-M-stimulated human CD134 expressing T lymphocytes. Figure 2 Binding of mouse anti-human CD134 antibodies clone 12H3 and clone 20E5 on PHA-M-stimulated human CD134 expressing CD4 T lymphocytes and CD8 T lymphocytes. Figure 3 Dose effect of exposure to mouse anti-human CD134 antibodies clone 12H3 or clone 20E5, or to human OX40L on proliferation of PHA-M-stimulated human CD134 expressing T lymphocytes. Figure 4 Effect of combining mouse anti-human CD134 antibodies clone 12H3 with human OX40L, or mouse anti-human CD134 antibodies clone 20E5 with human OX40L on proliferation of PHA-M-stimulated human CD134 expressing T lymphocytes. Figure 5 Effect of exposure to mouse anti-human CD134 antibodies clone 12H3 or clone 20E5, or to human OX40L on proliferation of anti-human CD3/anti-human CD28 antibody stimulator beads-stimulated human CD134 expressing human regulatory T lymphocytes.
Figure 1 High expression in lymph node. Figure 2 Tonsil Figure 3 RNA cell line category: Group enriched (MOLT-4, NB-4)

Specifications

  • Immunogen
  • Human CD134-transfected Sf9 insect cell lysates
  • Host Species
  • Mouse
  • Specificity
  • Human
  • Clone
  • 20E5
  • Applications
  • FuncS, FC
  • Related Disease
  • Cancers expressing CD134

Applications

  • Application Notes
  • The antibody was validated for Functional Assay, Flow Cytometry. For details, refer to Published Data.

Target

  • Alternative Names
  • TNFRSF4; tumor necrosis factor receptor superfamily, member 4; OX40; ACT35; CD134; IMD16; TXGP1L; tumor necrosis factor receptor superfamily member 4; OX40 antigen; ACT35 antigen; ATC35 antigen; CD134 antigen; OX40 homologue; OX40L receptor; OX40 cell surface antigen; lymphoid activation antigene ACT35; TAX transcriptionally-activated glycoprotein 1 receptor; tax-transcriptionally activated glycoprotein 1 receptor
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Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Datasheet

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COA

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