Afuco™ Anti-Human UNC5B ADCC Recombinant Antibody, ADCC Enhanced
CAT#: AFC-628CL
Anti-UNC5B ADCC Enhanced Antibody is an ADCC enhanced antibody produced by our Afuco™ platform. The anti-Unc5B antibodies are used to treat or prevent disorders associated with abnormal angiogenesis. These include solid tumors and metastasis, atherosclerosis, retrolental fibroplasia, hemangiomas, chronic inflammation, intraocular neovascular diseases such as proliferative retinopathies, age-related macular degeneration (AMD), neovascular glaucoma, immune rejection of transplanted corneal tissue and other tissues, rheumatoid arthritis, and psoriasis.
Gene Expression
Normal Tissue
Figure 1 IHC staining of human small intestine
Immunohistochemical staining of human small intestine shows strong cytoplasmic positivity in glandular cells.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/76687/166866_A_4_2_selected.jpg
Normal Tissue
Figure 2 Cerebral cortex
Neuronal cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous Neuropil Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/76687/166866_B_8_5.jpg
Normal Tissue
Figure 3 Kidney
Cells in glomeruli Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Cells in tubules Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/76687/166866_A_8_5.jpg
Normal Tissue
Figure 4 Testis
Elongated or late spermatids Staining: Low Intensity: Moderate Quantity: <25% Leydig cells Staining: High Intensity: Strong Quantity:>75%
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/76687/166866_A_6_6.jpg
Normal Tissue
Figure 5 Seminal vesicle
Glandular cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/76687/166866_A_9_6.jpg
Normal Tissue
Figure 6 Lymph node
Germinal center cells Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous Non-germinal center cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/76687/166866_A_9_8.jpg
RNA Expression
Figure 7 RNA cell line category: Cell line enhanced (HaCaT, HHSteC, hTCEpi, SH-SY5Y)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000107731-UNC5B
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Specifications
- Host Species
- Human
- Type
- ADCC enhanced antibody
- Species Reactivity
- Human
- Related Disease
- Cancer
Product Property
- Purity
- >90% assessed by SDS-PAGE
- Storage
- Store at -20°C. Avoid multiple freeze/thaw cycles.
Target
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Downloadable Resources
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "UNC5B"
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-229CQ | Anti-Human UNC5B Recombinant Antibody (YW83.21) | ELISA, FC, WB | Human antibody |
| TAB-229CQ-S(P) | Anti-Human UNC5B Recombinant Antibody scFv Fragment (YW83.21) | ELISA, FC, WB | Human antibody |
| TAB-229CQ-F(E) | Anti-Human UNC5B Recombinant Antibody Fab Fragment (YW83.21) | ELISA, FC, WB | Human antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0058CQ-S(P) | Human Anti-UNC5B Recombinant Antibody (clone YW88.82); scFv Fragment | WB, FC, Block | Human scFv |
| HPAB-0059CQ-S(P) | Human Anti-UNC5B Recombinant Antibody (clone YW83.7); scFv Fragment | WB, FC | Human scFv |
| HPAB-AP840-YC-S(P) | Human Anti-UNC5B Recombinant Antibody (clone AP014/YC); scFv Fragment | ELISA, FC, WB | Human scFv |
| HPAB-AP841-YC-S(P) | Human Anti-UNC5B Recombinant Antibody (clone AP015/YC); scFv Fragment | ELISA, FC, WB | Human scFv |
| HPAB-AP842-YC-S(P) | Human Anti-UNC5B Recombinant Antibody (clone AP016/YC); scFv Fragment | ELISA, FC, WB | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0058CQ-F(E) | Human Anti-UNC5B Recombinant Antibody (clone YW88.82); Fab Fragment | WB, FC, Block | Human Fab |
| HPAB-0059CQ-F(E) | Human Anti-UNC5B Recombinant Antibody (clone YW83.7); Fab Fragment | WB, FC | Human Fab |
| HPAB-AP840-YC-F(E) | Human Anti-UNC5B Recombinant Antibody (clone AP014/YC); Fab Fragment | ELISA, FC, WB | Human Fab |
| HPAB-AP841-YC-F(E) | Human Anti-UNC5B Recombinant Antibody (clone AP015/YC); Fab Fragment | ELISA, FC, WB | Human Fab |
| HPAB-AP842-YC-F(E) | Human Anti-UNC5B Recombinant Antibody (clone AP016/YC); Fab Fragment | ELISA, FC, WB | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-AP840-YC | Human Anti-UNC5B Recombinant Antibody (clone AP014/YC) | ELISA, FC, WB | Human IgG |
| HPAB-AP841-YC | Human Anti-UNC5B Recombinant Antibody (clone AP015/YC) | ELISA, FC, WB | Human IgG |
| HPAB-AP842-YC | Human Anti-UNC5B Recombinant Antibody (clone AP016/YC) | ELISA, FC, WB | Human IgG |
| FAMAB-0713WJ | Mouse Anti-UNC5B Recombinant Antibody (clone 1.2.1) | ELISA, WB | Mouse IgG |
| FAMAB-0714WJ | Mouse Anti-UNC5B Recombinant Antibody (clone 1.2.2) | ELISA, WB | Mouse IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-YC652 | Recombinant Anti-UNC5B Vesicular Antibody, EV Displayed (VS-0425-YC652) | Block, ELISA, FC, Cell-uptake |
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