Recombinant Mouse Anti-Human UNC5B Antibody (clone Hvjep-2)
CAT#: MOB-1239MZ
This antibody is a recombinant mouse monoclonal antibody which specifically reacts with human UNC5B.
Gene Expression
Normal Tissue
Figure 1 IHC staining of human small intestine
Immunohistochemical staining of human small intestine shows strong cytoplasmic positivity in glandular cells.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/76687/166866_A_4_2_selected.jpg
Normal Tissue
Figure 2 Cerebral cortex
Neuronal cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous Neuropil Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/76687/166866_B_8_5.jpg
Normal Tissue
Figure 3 Kidney
Cells in glomeruli Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Cells in tubules Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/76687/166866_A_8_5.jpg
Normal Tissue
Figure 4 Testis
Elongated or late spermatids Staining: Low Intensity: Moderate Quantity: <25% Leydig cells Staining: High Intensity: Strong Quantity:>75%
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/76687/166866_A_6_6.jpg
Normal Tissue
Figure 5 Seminal vesicle
Glandular cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/76687/166866_A_9_6.jpg
Normal Tissue
Figure 6 Lymph node
Germinal center cells Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous Non-germinal center cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/76687/166866_A_9_8.jpg
RNA Expression
Figure 7 RNA cell line category: Cell line enhanced (HaCaT, HHSteC, hTCEpi, SH-SY5Y)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000107731-UNC5B
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Specifications
- Immunogen
- Recombinant fragment, corresponding to amino acids 28-363 of Human UNC5B
- Host Species
- Mouse
- Type
- Mouse antibody
- Specificity
- Human UNC5B
- Species Reactivity
- Human
- Clone
- Hvjep-2
- Applications
- FC, ICC, IF
Target
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Reliable Research Tool
Using the Recombinant Anti-Human UNC5B Antibody has significantly streamlined my research. The antibody showed remarkable specificity and sensitivity in our flow cytometry experiments, consistently delivering reliable results.
Great Performance
Our transition to UNC5B antibodies from Creative Biolabs has been fantastic. The outstanding performance in ICC/IF applications has made complex interactions easier to visualize. Delivery was prompt, and the technical support provided exceeded expectations. Their expertise helped optimize our experiment protocols, ensuring top-notch results.
Versatile Application
The versatility of this antibody across multiple applications is impressive. It has adapted well in our antibody-coupled liposome development studies, proving its broad functional scope.
Q&As
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What research applications can the Recombinant Anti-Human UNC5B Antibody be used for?
A: The Recombinant Anti-Human UNC5B Antibody can be utilized in various research applications such as flow cytometry (FC), immunocytochemistry/immunofluorescence (ICC/IF), and other cell signaling studies. It is particularly valuable in neuroscience and cancer biomarker research, providing insights into cell signalling pathways and protein interactions, which are critical for understanding tumourigenesis and neuronal cell behavior.
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How can the UNC5B antibody help in studying cancer's underlying mechanisms?
A: UNC5B is a receptor involved in cell survival and apoptosis, playing a significant role in cancer biology. Understanding how UNC5B interactions trigger apoptosis pathways can be crucial for developing cancer treatments. This antibody helps researchers identify the expression patterns of UNC5B in various cell types, providing a detailed understanding of its role in cancer progression and metastasis.
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What specific targets does the Recombinant Anti-Human UNC5B Antibody bind to?
A: This antibody targets the human UNC5B receptor, which is part of the netrin receptor family critical in neural development and axon guidance. Such specificity makes it instrumental in studying pathways involving cellular adhesion and migration, providing clarity on how these processes might go awry in diseases.
View the frequently asked questions answered by Creative Biolabs Support.
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Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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Protocol & Troubleshooting
We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.
See other products for "UNC5B"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-229CQ | Anti-Human UNC5B Recombinant Antibody (YW83.21) | ELISA, FC, WB | Human antibody |
| TAB-229CQ-S(P) | Anti-Human UNC5B Recombinant Antibody scFv Fragment (YW83.21) | ELISA, FC, WB | Human antibody |
| TAB-229CQ-F(E) | Anti-Human UNC5B Recombinant Antibody Fab Fragment (YW83.21) | ELISA, FC, WB | Human antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0058CQ-S(P) | Human Anti-UNC5B Recombinant Antibody (clone YW88.82); scFv Fragment | WB, FC, Block | Human scFv |
| HPAB-0059CQ-S(P) | Human Anti-UNC5B Recombinant Antibody (clone YW83.7); scFv Fragment | WB, FC | Human scFv |
| HPAB-0060CQ-S(P) | Human Anti-UNC5B Recombinant Antibody (clone YW83.4); scFv Fragment | WB, FC | Human scFv |
| HPAB-0061CQ-S(P) | Human Anti-UNC5B Recombinant Antibody (clone YW88.7); scFv Fragment | WB, FC, Block | Human scFv |
| HPAB-AP840-YC-S(P) | Human Anti-UNC5B Recombinant Antibody (clone AP014/YC); scFv Fragment | ELISA, FC, WB | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0058CQ-F(E) | Human Anti-UNC5B Recombinant Antibody (clone YW88.82); Fab Fragment | WB, FC, Block | Human Fab |
| HPAB-0059CQ-F(E) | Human Anti-UNC5B Recombinant Antibody (clone YW83.7); Fab Fragment | WB, FC | Human Fab |
| HPAB-AP840-YC-F(E) | Human Anti-UNC5B Recombinant Antibody (clone AP014/YC); Fab Fragment | ELISA, FC, WB | Human Fab |
| HPAB-AP841-YC-F(E) | Human Anti-UNC5B Recombinant Antibody (clone AP015/YC); Fab Fragment | ELISA, FC, WB | Human Fab |
| HPAB-AP842-YC-F(E) | Human Anti-UNC5B Recombinant Antibody (clone AP016/YC); Fab Fragment | ELISA, FC, WB | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-AP840-YC | Human Anti-UNC5B Recombinant Antibody (clone AP014/YC) | ELISA, FC, WB | Human IgG |
| HPAB-AP841-YC | Human Anti-UNC5B Recombinant Antibody (clone AP015/YC) | ELISA, FC, WB | Human IgG |
| HPAB-AP842-YC | Human Anti-UNC5B Recombinant Antibody (clone AP016/YC) | ELISA, FC, WB | Human IgG |
| FAMAB-0713WJ | Mouse Anti-UNC5B Recombinant Antibody (clone 1.2.1) | ELISA, WB | Mouse IgG |
| FAMAB-0714WJ | Mouse Anti-UNC5B Recombinant Antibody (clone 1.2.2) | ELISA, WB | Mouse IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-YC652 | Recombinant Anti-UNC5B Vesicular Antibody, EV Displayed (VS-0425-YC652) | Block, ELISA, FC, Cell-uptake |
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