Recombinant Anti-MET × Anti-EGFR Bispecific Antibody (Tandem Diabody) (CAT#: TAND-L008)
Recombinant Anti-MET × Anti-EGFR Bispecific Antibody (Tandem Diabody) is a bispecific fusion protein with four binding sites, two of which bind to antigens of one kind of cells and the other two to the other kind of cells. Tandem Diabodies do not carry Fc domains. So they are smaller than whole IgGs or IgG-derived BsAbs but larger than tandem scFvs. Therefore, they have a shorter serum half-life than IgGs but remain longer in the circulation compared with tandem scFvs. This BsAb can simultaneously block two receptors. It was designed for the treatment of colorectal cancer, pancreatic cancer, head and neck cancer, and non-small cell lung cancer (NSCLC).
Specific Inquiry
Specifications
- Target
- MET & EGFR
- Type
- Tandem Diabody
- Species Reactivity
- Human
- Target 1
- MET
- Host Species 1
- Mouse
- Target 2
- EGFR
- Host Species 2
- Mouse
- Application
- FuncS, Promising therapeutic agent
- Related Disease
- Colorectal cancer, Pancreatic cancer, Head and neck cancer, and Non-small cell lung cancer (NSCLC)
Target
- Target 1
- MET
- Gene ID
- 4233
- UniProt ID
- A0A024R759
- Alternative Names
- MET; MET proto-oncogene, receptor tyrosine kinase; HGFR; AUTS9; RCCP2; c-Met; hepatocyte growth factor receptor; SF receptor; HGF receptor; HGF/SF receptor; proto-oncogene c-Met; scatter factor receptor; tyrosine-protein kinase Met; met proto-oncogene tyr
- Target 2
- EGFR
- Gene ID
- 1956
- UniProt ID
- P00533
- Alternative Names
- EGFR; epidermal growth factor receptor; ERBB; HER1; mENA; ERBB1; PIG61; NISBD2; proto-oncogene c-ErbB-1; cell growth inhibiting protein 40; erb-b2 receptor tyrosine kinase 1; cell proliferation-inducing protein 61; receptor tyrosine-protein kinase erbB-1; avian erythroblastic leukemia viral (v-erb-b) oncogene homolog
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "MET & EGFR"
Select a product category from the dropdown menu below to view related products.
Please select product type
Triplebody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TRIAB-MZ006 | Recombinant Anti-MET × Anti-EGFR Bispecific Antibody (Triplebody) | WB, ICC | Triplebody |
| TRIAB-MZ007 | Recombinant Mouse Anti-MET × Anti-EGFR Bispecific Antibody (Triplebody) | FC | Triplebody |
Customer Reviews and Q&As
There are currently no Customer reviews or questions for TAND-L008. Click the button above to contact us or submit your feedback about this product.
Popular products with customers
Application: Neut, ELISA, IF, IP, FuncS, FC, ICC
Application: ELISA, Neut, IF, IP, FC, FuncS
Application: IP, IF, FuncS, FC, Neut, ELISA, ICC
Application: IF, IP, Neut, FuncS, ELISA, FC, WB
Application: IF, IP, Neut, FuncS, ELISA, FC, WB
Application: WB, ELISA, FC, IP, FuncS, IF, Neut
-1.jpg)
-1.jpg)
Application: ELISA, IHC, FC, IP, IF, BL
Application: ELISA, IHC, FC, IP, IF, Inhib
Application: FC, IHC, Cyt, FuncS
Application: ELISA, Inhib, FC, Neut
Application: FC
Application: ELISA, FC, WB, Inhib, IHC
For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
Send Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
