Cdc53 scaffold protein anti-Human Skp1
CAT#: SCC-L250
The Cdc53 that bound Skp1 was isolated from the library using phage display techonology. After affinity maturation, Cdc53 variants were identified having affinities for Skp1 as determined by biosensor technology. It's potential to be used in diagnostic, research and therapeutic applications.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line MCF7
Immunofluorescent staining of human cell line MCF7 shows localization to nucleoplasm & cytosol.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/53745/if_selected.jpg
Subcellular Location
Figure 2 IF staining of human cell line MCF7
Immunofluorescent staining of human cell line MCF7 shows localization to nucleoplasm.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/58134/if_selected.jpg
Normal Tissue
Figure 3 IHC staining of human gallbladder
Immunohistochemical staining of human gallbladder shows moderate cytoplasmic and nuclear positivity in glandular cells.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/12982/31727_A_6_4_selected.jpg
Normal Tissue
Figure 4 Lymph node
Germinal center cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: nuclear Non-germinal center cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/12982/31727_A_7_8.jpg
Normal Tissue
Figure 5 Cerebral cortex
Glial cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous Neuronal cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous nuclear Neuropil Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/12982/31727_B_7_5.jpg
Normal Tissue
Figure 6 Cerebellum
Cells in granular layer Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous Cells in molecular layer Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous nuclear Purkinje cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/12982/31727_B_7_8.jpg
Normal Tissue
Figure 7 Colon
Glandular cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Nuclear Peripheral nerve/ganglion Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/12982/31727_A_8_3.jpg
RNA Expression
Figure 8 RNA cell line category: Low cell line specificity
Cell lines ordered by descending RNA expression order
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000113558-SKP1
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Specifications
- Scaffold Name
- Cdc53
- Origin
- Cdc53
- Target
- Skp1
- Species Reactivity
- Human
- Expression Host
- E. coli
- Applications
- ELISA; IHC; Microscopy; FC; WB; FuncS
Target
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Related Signaling Pathways
TGF-β Signaling Pathway
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See other products for "SKP1"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1783MZ | Recombinant Mouse Anti-Human SKP1 Antibody | WB | Mouse antibody |
| VS3-XY1424 | Mouse Anti-SKP1 Recombinant Antibody (clone 4E11C10) | IHC, ICC, FC | Mouse IgG1 |
| VS3-FY1342 | Recombinant Rabbit Anti-SKP1 Antibody (clone R01-6H2) | WB, ICC, IF | Rabbit IgG |
| VS7-0425-WR866 | Mouse Anti-SKP1 Monoclonal Antibody (clone 1H9) | WB, IHC, FC | Mouse IgG1 |
| VS7-0425-WR867 | Mouse Anti-SKP1 Monoclonal Antibody (clone 4E11) | WB, IHC, ICC, FC | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-3274 | Hi-Affi™ Recombinant Rabbit Anti-SKP1 Monoclonal Antibody (DS3274AB) | WB, FC, ICC, IF | IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-1024-XY482 | Mouse Anti-NHP SKP1 Recombinant Antibody (clone 4E11) | WB, IHC, ICC, FC, ELISA | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-XY2079 | Anti-SKP1 Immunohistochemistry Kit | IHC |
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