H-2Kb/HBV HBsAg (ILSPFLPLL) MHC Tetramer
CAT#: MHC-LC736
This product is a tetramer of biotinylated peptide/MHC complex with streptavidin mainly composed of HBV-derived peptide of ILSPFLPLL sequence covering 208-216 and H-2Kb molecule. The pMHC tetramer recognizes mouse CD8 T cells, and can be used in the analysis of individual antigen-specific T cells.
Specifications
- Allele
- H-2Kb
- Class
- Class I
- MHC Species
- Mouse
- Antigen
- HBV HBsAg
- Antigen Species
- HBV
- Peptide
- ILSPFLPLL
- Range
- 208-216
- Application
- FCM
Target
- Antigen Introduction
- Hepatitis B virus, abbreviated HBV, is of the double stranded DNA type, a species of the genus Orthohepadnavirus, which is likewise a part of the Hepadnaviridae family of viruses. This virus causes the disease hepatitis B.
- Alternative Names
- HBV surface antigen; Hepatitis B virus surface antigen; HBsAg
- Gene ID
- 944569
- UniProt ID
- Q2F515
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Exceptional Specificity
This MHC tetramer's exceptional specificity for HBV-specific CD8 T cells has greatly enhanced the reliability of our flow cytometry assays. It's a fundamental tool in our efforts to analyze immune responses with clarity and precision.
Success in Hepatitis Research
In hepatitis research, this MHC tetramer is indispensable. The insights it provides into HBV-specific immune responses boost our understanding and guide our approaches to therapeutic interventions and vaccine development.
Q&As
-
What is the main use of the H-2Kb/HBV HBsAg MHC Tetramer?
A: This tetramer is primarily designed for flow cytometry, allowing researchers to identify and quantify CD8 T cells specific to the Hepatitis B surface antigen (HBsAg) in mouse models. This focus aids in understanding HBV-specific immune responses more thoroughly.
-
How does the ILSPFLPLL peptide sequence function in the tetramer?
A: The ILSPFLPLL peptide is derived from the Hepatitis B virus surface antigen, providing specificity for detecting HBV-specific CD8 T cells. This sequence enhances the reliability of studying T cell-mediated immune responses against HBV.
View the frequently asked questions answered by Creative Biolabs Support.
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Downloadable Resources
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Datasheet
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