PE-A*02:01/Human FASN (FLFDGSPTYVL) MHC Tetramer
CAT#: MHC-LC1986
This product is a tetramer of biotinylated peptide/MHC complex with streptavidin mainly composed of human FASN of peptide FLFDGSPTYVL covering 2335-2345 and A*02:01 molecule. The pMHC tetramer recognizes CD8 T cells, and can be used in the analysis of individual antigen-specific T cells.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line A-431
Immunofluorescent staining of human cell line A-431 shows localization to plasma membrane & cytosol.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/6461/if_selected.jpg
Subcellular Location
Figure 2 IF staining of human cell line U-2 OS
Immunofluorescent staining of human cell line U-2 OS shows localization to cytosol.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/5192/if_selected.jpg
Normal Tissue
Figure 3 Cerebral cortex
Neuronal cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/6461/155195_B_8_5.jpg
Normal Tissue
Figure 4 Testis
Leydig cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/6461/155195_A_4_6.jpg
Normal Tissue
Figure 5 Breast
Adipocytes Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous Glandular cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/6461/155195_B_3_4.jpg
Normal Tissue
Figure 6 Lymph node
Non-germinal center cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/6461/155195_A_9_8.jpg
RNA Expression
Figure 7 RNA cell line category: Cell line enhanced (SK-BR-3)
Cell lines ordered by descending RNA expression order
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000169710-FASN
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Specifications
- Allele
- A*02:01
- Class
- Class I
- MHC Species
- Human
- Antigen
- FASN
- Antigen Species
- Human
- Peptide
- FLFDGSPTYVL
- Range
- 2335-2345
- Conjugate
- PE
- Application
- FCM
Target
- Antigen Introduction
- The enzyme encoded by this gene is a multifunctional protein. Its main function is to catalyze the synthesis of palmitate from acetyl-CoA and malonyl-CoA, in the presence of NADPH, into long-chain saturated fatty acids. In some cancer cell lines, this protein has been found to be fused with estrogen receptor-alpha (ER-alpha), in which the N-terminus of FAS is fused in-frame with the C-terminus of ER-alpha. [provided by RefSeq, Jul 2008]
- Alternative Names
- FASN; Fatty acid synthase; FAS; OA-519; SDR27X1
- Gene ID
- 2194
- UniProt ID
- P49327
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Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-3035z | Mouse Anti-FASN Recombinant Antibody (clone 36H1) | WB, ICC, IF | Mouse IgG1, κ |
| MOB-0705CT | Recombinant Mouse anti-Human FASN Monoclonal antibody (3F2-1F3) | WB | |
| MRO-1855-CN | Rabbit Anti-FASN Polyclonal Antibody (MRO-1855-CN) | WB, IF, IHC | Rabbit IgG |
| ZG-0665J | Rabbit Anti-FASN Recombinant Antibody (clone 2A5) | ELISA, IF, FC | Rabbit IgG |
| VS3-CJ985 | Mouse Anti-FASN Recombinant Antibody (VS3-CJ985) | WB, ICC | Mouse IgM |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-1254 | Hi-Affi™ Rabbit Anti-FASN Recombinant Antibody (clone DS1254AB) | WB, IHC, ICC, FC | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHC-LC1941 | PE-A2/Human FASN (FLFDGSPTYVL) MHC Tetramer | FCM | |
| MHC-LC1942 | PE-A2/Human FASN (FLFDGSPTYV) MHC Tetramer | FCM | |
| MHC-LC1963 | APC-A2/Human FASN (FLFDGSPTYV) MHC Tetramer | FCM | |
| MHC-LC1964 | APC-A2/Human FASN (FLFDGSPTYVL) MHC Tetramer | FCM |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS3-QX416 | Mouse Anti-FASN Recombinant Antibody (clone 497CT15.2.5) | WB, ICC | Mouse IgM |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0424-XY98 | AbPlus™ Anti-FASN Magnetic Beads (2F9-B2-B6) | IP, Protein Purification | |
| VS-0724-YC513 | AbPlus™ Anti-FASN Magnetic Beads (VS-0724-YC513) | IP, Protein Purification |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-XY816 | Anti-FASN Immunohistochemistry Kit | IHC | |
| VS-0525-XY2452 | Anti-Mouse FASN Immunohistochemistry Kit | IHC | |
| VS-0525-XY2451 | Anti-Human FASN Immunohistochemistry Kit | IHC |
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