APC-A2/Human FASN (FLFDGSPTYVL) MHC Tetramer (CAT#: MHC-LC1964)
This product is a tetramer of biotinylated peptide/MHC complex with streptavidin mainly composed of human FASN of peptide FLFDGSPTYVL covering 2335-2345 and A2 molecule. The pMHC tetramer recognizes CD8 T cells, and can be used in the analysis of individual antigen-specific T cells.
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MHC tetramer custom production provides a vital tool for researchers seeking to understand and manipulate T-cell immunity with exceptional precision. Please specify your requirements, including peptide sequence, MHC allele, and desired fluorophore etc. We will respond as soon as possible with a tailored solution.
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Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line A-431
(Immunofluorescent staining of human cell line A-431 shows localization to plasma membrane & cytosol.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/6461/if_selected.jpg
(Immunofluorescent staining of human cell line A-431 shows localization to plasma membrane & cytosol.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/6461/if_selected.jpg
Figure 2 IF staining of human cell line U-2 OS
(Immunofluorescent staining of human cell line U-2 OS shows localization to cytosol.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/5192/if_selected.jpg
(Immunofluorescent staining of human cell line U-2 OS shows localization to cytosol.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/5192/if_selected.jpg
Figure 3 Cerebral cortex
(Neuronal cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/6461/155195_B_8_5.jpg
(Neuronal cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/6461/155195_B_8_5.jpg
Figure 4 Testis
(Leydig cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/6461/155195_A_4_6.jpg
(Leydig cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/6461/155195_A_4_6.jpg
Figure 5 Breast
(Adipocytes Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous Glandular cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/6461/155195_B_3_4.jpg
(Adipocytes Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous Glandular cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/6461/155195_B_3_4.jpg
Figure 6 Lymph node
(Non-germinal center cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/6461/155195_A_9_8.jpg
(Non-germinal center cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/6461/155195_A_9_8.jpg
Figure 7 RNA cell line category: Cell line enhanced (SK-BR-3)
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000169710-FASN
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000169710-FASN
Specifications
- Allele
- A2
- Class
- Class I
- MHC Species
- Human
- Antigen
- FASN
- Antigen Species
- Human
- Peptide
- FLFDGSPTYVL
- Range
- 2335-2345
- Conjugate
- APC
- Application
- FCM
Target
- Antigen Introduction
- The enzyme encoded by this gene is a multifunctional protein. Its main function is to catalyze the synthesis of palmitate from acetyl-CoA and malonyl-CoA, in the presence of NADPH, into long-chain saturated fatty acids. In some cancer cell lines, this protein has been found to be fused with estrogen receptor-alpha (ER-alpha), in which the N-terminus of FAS is fused in-frame with the C-terminus of ER-alpha. [provided by RefSeq, Jul 2008]
- Alternative Names
- FASN; Fatty acid synthase; FAS; OA-519; SDR27X1
- Gene ID
- 2194
- UniProt ID
- P49327
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-0705CT | Recombinant Mouse anti-Human FASN Monoclonal antibody (3F2-1F3) | WB | |
| MRO-1855-CN | Rabbit Anti-FASN Polyclonal Antibody (MRO-1855-CN) | WB, IF, IHC | Rabbit IgG |
| VS3-QX414 | Mouse Anti-FASN Recombinant Antibody (clone 2F9-B2-B6) | WB, IP, IF | Mouse IgG2a |
| VS3-QX415 | Mouse Anti-FASN Recombinant Antibody (clone 6B9-H12-E7) | WB, IP, IF | Mouse IgG1 |
| VS3-CJ985 | Mouse Anti-FASN Recombinant Antibody (VS3-CJ985) | WB, ICC | Mouse IgM |
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