PE-A2/Human FASN (FLFDGSPTYV) MHC Tetramer (CAT#: MHC-LC1942)
This product is a tetramer of biotinylated peptide/MHC complex with streptavidin mainly composed of human FASN of peptide FLFDGSPTYV covering 2333-2342 and A2 molecule. The pMHC tetramer recognizes CD8 T cells, and can be used in the analysis of individual antigen-specific T cells.
Specific Inquiry
Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line A-431
(Immunofluorescent staining of human cell line A-431 shows localization to plasma membrane & cytosol.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/6461/if_selected.jpg
(Immunofluorescent staining of human cell line A-431 shows localization to plasma membrane & cytosol.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/6461/if_selected.jpg
Figure 2 IF staining of human cell line U-2 OS
(Immunofluorescent staining of human cell line U-2 OS shows localization to cytosol.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/5192/if_selected.jpg
(Immunofluorescent staining of human cell line U-2 OS shows localization to cytosol.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/5192/if_selected.jpg
Figure 3 Cerebral cortex
(Neuronal cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/6461/155195_B_8_5.jpg
(Neuronal cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/6461/155195_B_8_5.jpg
Figure 4 Testis
(Leydig cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/6461/155195_A_4_6.jpg
(Leydig cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/6461/155195_A_4_6.jpg
Figure 5 Breast
(Adipocytes Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous Glandular cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/6461/155195_B_3_4.jpg
(Adipocytes Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous Glandular cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/6461/155195_B_3_4.jpg
Figure 6 Lymph node
(Non-germinal center cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/6461/155195_A_9_8.jpg
(Non-germinal center cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/6461/155195_A_9_8.jpg
Figure 7 RNA cell line category: Cell line enhanced (SK-BR-3)
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000169710-FASN
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000169710-FASN
Specifications
- Allele
- A2
- Class
- Class I
- Antigen
- FASN
- Antigen Species
- Human
- Peptide
- FLFDGSPTYV
- Range
- 2333-2342
- Conjugate
- PE
- Application
- FCM
Target
- Antigen Introduction
- The enzyme encoded by this gene is a multifunctional protein. Its main function is to catalyze the synthesis of palmitate from acetyl-CoA and malonyl-CoA, in the presence of NADPH, into long-chain saturated fatty acids. In some cancer cell lines, this protein has been found to be fused with estrogen receptor-alpha (ER-alpha), in which the N-terminus of FAS is fused in-frame with the C-terminus of ER-alpha. [provided by RefSeq, Jul 2008]
- Alternative Names
- FASN; fatty acid synthase; FAS; OA-519; SDR27X1
- Gene ID
- 2194
- UniProt ID
- P49327
Downloads
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Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-3035z | Mouse Anti-FASN Recombinant Antibody (clone 36H1) | WB, ICC, IF | Mouse IgG1, κ |
| MOB-0705CT | Recombinant Mouse anti-Human FASN Monoclonal antibody (3F2-1F3) | WB | |
| MRO-0571-CN | Rabbit Anti-FASN Recombinant Antibody (clone JJ0939) | WB, IF, IHC, IP, FC | Rabbit IgG |
| MRO-1855-CN | Rabbit Anti-FASN Polyclonal Antibody (MRO-1855-CN) | WB, IF, IHC | Rabbit IgG |
| VS3-CJ19 | Mouse Anti-FASN Recombinant Antibody (VS3-CJ19) | WB, ELISA | Mouse IgG |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-1254 | Hi-Affi™ Rabbit Anti-FASN Recombinant Antibody (clone DS1254AB) | WB, IHC, ICC, FC | Rabbit IgG |
MHC Tetramer for Cancer
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHC-LC1941 | PE-A2/Human FASN (FLFDGSPTYVL) MHC Tetramer | FCM | |
| MHC-LC1963 | APC-A2/Human FASN (FLFDGSPTYV) MHC Tetramer | FCM | |
| MHC-LC1964 | APC-A2/Human FASN (FLFDGSPTYVL) MHC Tetramer | FCM | |
| MHC-LC1986 | PE-A*02:01/Human FASN (FLFDGSPTYVL) MHC Tetramer | FCM |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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