AbPlus™ Anti-FASN Magnetic Beads (2F9-B2-B6) (CAT#: VS-0424-XY98)

• Applications
• Immunoprecipitation, Protein Purification

• Matrix
• Magrose bead (> 50 μmol/mL gel)

• Bead Ligand
• Anti-FASN specific antibody (2F9-B2-B6)

• Target
• FASN

• Immunogen
• Purified recombinant human fatty acid synthase protein expressed in E. coli

• Target Species
• Human, Mouse, Rat, Monkey

• Antibody Clone
• 2F9-B2-B6

• Bead Capacity
• 20-30 mg/mL binding antibody

• Bead size
• 10-37 μm

• Stability
• pH 2-14

• Format
• 20% Suspension

• Buffer
• PBS, pH 7.4, with 1% BSA

• Preservative
• 0.03% Proclin 300

• Storage
• Stored at 4°C, and is stable for up to 2 years. Do not centrifuge, dry or freeze the magnetic beads.

• Application Notes
• The beads are in suspension and will settle upon storage. Prior to use, mix the vial gently (do not vortex) to ensure delivery of proper bead volume.

• Introduction
• The enzyme encoded by this gene is a multifunctional protein. Its main function is to catalyze the synthesis of palmitate from acetyl-CoA and malonyl-CoA, in the presence of NADPH, into long-chain saturated fatty acids. In some cancer cell lines, this protein has been found to be fused with estrogen receptor-alpha (ER-alpha), in which the N-terminus of FAS is fused in-frame with the C-terminus of ER-alpha.

• Alternative Names
• FAS; OA-519; SDR27X1

• Gene ID
• 2194

• UniProt ID
• P49327

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