PE-A*03:01/Human MLANA (LIGCWYCRRR) MHC Tetramer (CAT#: MHC-LC3013)
This product is a tetramer of biotinylated peptide/MHC complex with streptavidin mainly composed of human MLANA of peptide LIGCWYCRRR covering 42-51 and A*03:01 molecule. The pMHC tetramer recognizes CD8 T cells, and can be used in the analysis of individual antigen-specific T cells.
Specific Inquiry
Custom Production
MHC tetramer custom production provides a vital tool for researchers seeking to understand and manipulate T-cell immunity with exceptional precision. Please specify your requirements, including peptide sequence, MHC allele, and desired fluorophore etc. We will respond as soon as possible with a tailored solution.
We require custom production
Normal Tissue
RNA Expression
Figure 1 High expression in skin 1
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/48662/167996_B_8_1_val_selected.jpg
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/48662/167996_B_8_1_val_selected.jpg
Figure 2 Low expression in liver
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/48662/167996_A_8_4_val_selected.jpg
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/48662/167996_A_8_4_val_selected.jpg
Figure 3 Testis
(Leydig cells Staining: Not detected Intensity: Weak Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/48662/167996_A_5_6.jpg
(Leydig cells Staining: Not detected Intensity: Weak Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/48662/167996_A_5_6.jpg
Figure 4 RNA cell line category: Cell line enriched (SK-MEL-30)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000120215-MLANA
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000120215-MLANA
Specifications
- Allele
- A*03:01
- Class
- Class I
- MHC Species
- Human
- Antigen
- MLANA
- Antigen Species
- Human
- Peptide
- LIGCWYCRRR
- Range
- 42-51
- Conjugate
- PE
- Application
- FCM
Target
- Antigen Introduction
- Protein melan-A also known as melanoma antigen recognized by T cells 1 or MART-1 is a protein that in humans is encoded by the MLANA o "MALENA" gene. A fragment of the protein, usually consisting of the nine amino acids 27 to 35, is bound by MHC class I complexes which present it to T cells of the immune system. These complexes can be found on the surface of melanoma cells. Decameric peptides (26-35) are being investigated as cancer vaccines.
- Alternative Names
- MLANA; melan-A; MART1; MART-1
- Gene ID
- 2315
- UniProt ID
- Q16655
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "MLANA"
Select a product category from the dropdown menu below to view related products.
Please select product type
IgG Antibody Products
Single Domain Antibody Products
Immunotoxin Products
MHC Tetramer Products for Cancer
Rabbit Monoclonal Antibody Products
Epitope-Specific Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1380z | Mouse Anti-MLANA Recombinant Antibody (clone 22A7) | ELISA, FC, ICC, IF, IHC, WB | Mouse IgG1 |
| MOB-0324MZ | Recombinant Mouse Anti-Human MLANA Antibody (clone B104) | IHC | Mouse antibody |
| MOB-0096F | Mouse Anti-MLANA Recombinant Antibody (MOB-0096F) | IHC-P, IF | Mouse IgG |
| ZG-0354U | Rabbit Anti-MLANA Recombinant Antibody (clone A19-P) | IHC-P | Rabbit IgG |
| VS3-XY3428 | Rabbit Anti-MLANA Recombinant Antibody (clone R08-8B5) | WB, IHC-P, ICC, IF, FC | Rabbit IgG |
Customer Reviews and Q&As
There are currently no Customer reviews or questions for MHC-LC3013. Click the button above to contact us or submit your feedback about this product.
Popular products with customers
Application: WB, ELISA, FC, IP, FuncS, IF, Neut
Application: Neut, ELISA, IF, IP, FuncS, FC, IHC
Application: IF, IP, Neut, FuncS, ELISA, FC, WB
Application: Neut, ELISA, IF, IP, FuncS, FC, ICC
Application: FC, IHC, FuncS, Inhib, Cyt
Application: FuncS, IF, Neut, ELISA, FC, IP, ICC
Application: ELISA, WB, BLI, SPR
-2.png)
Application: WB, ELISA, FC, IHC, IP
Application: Neut, FC
For Research Use Only. Not For Clinical Use.
Send Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
