PE-A*11:01/Human RPS6 (SVLNLVIVK) MHC Tetramer

CAT#: MHC-LC2373

This product is a tetramer of biotinylated peptide/MHC complex with streptavidin mainly composed of human RPS6 of peptide SVLNLVIVK covering 107-115 and A*11:01 molecule. The pMHC tetramer recognizes CD8 T cells, and can be used in the analysis of individual antigen-specific T cells.

Gene Expression
Figure 1 Cerebral cortex Figure 2 Colon Figure 3 Pancreas Figure 4 Kidney Figure 5 Testis Figure 6 Lymph node Figure 7 RNA cell line category: Cell line enhanced (NB-4)

Specifications

  • Allele
  • A*11:01
  • Class
  • Class I
  • MHC Species
  • Human
  • Antigen
  • RPS6
  • Antigen Species
  • Human
  • Peptide
  • SVLNLVIVK
  • Range
  • 107-115
  • Conjugate
  • PE
  • Application
  • FCM

Target

  • Antigen Introduction
  • Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a cytoplasmic ribosomal protein that is a component of the 40S subunit. The protein belongs to the S6E family of ribosomal proteins. It is the major substrate of protein kinases in the ribosome, with subsets of five C-terminal serine residues phosphorylated by different protein kinases. Phosphorylation is induced by a wide range of stimuli, including growth factors, tumor-promoting agents, and mitogens. Dephosphorylation occurs at growth arrest. The protein may contribute to the control of cell growth and proliferation through the selective translation of particular classes of mRNA. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008]
  • Alternative Names
  • RPS6; 40S ribosomal protein S6; S6
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MHC-LC2372 PE-A*03:01/Human RPS6 (SVLNLVIVK) MHC Tetramer FCM
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