APC-B*07:02/Human EIF4G1 (AARPATSTL) MHC Tetramer
CAT#: MHC-LC2091
This product is a tetramer of biotinylated peptide/MHC complex with streptavidin mainly composed of human EIF4G1 of peptide AARPATSTL covering 1113-1121 and B*07:02 molecule. The pMHC tetramer recognizes CD8 T cells, and can be used in the analysis of individual antigen-specific T cells.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line A-431
Immunofluorescent staining of human cell line A-431 shows localization to cytosol & vesicles.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/43866/if_selected.jpg
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Specifications
- Allele
- B*07:02
- Class
- Class I
- MHC Species
- Human
- Antigen
- EIF4G1
- Antigen Species
- Human
- Peptide
- AARPATSTL
- Range
- 1113-1121
- Conjugate
- APC
- Application
- FCM
Target
- Antigen Introduction
- The protein encoded by this gene is a component of the multi-subunit protein complex EIF4F. This complex facilitates the recruitment of mRNA to the ribosome, which is a rate-limiting step during the initiation phase of protein synthesis. The recognition of the mRNA cap and the ATP-dependent unwinding of 5'-terminal secondary structure is catalyzed by factors in this complex. The subunit encoded by this gene is a large scaffolding protein that contains binding sites for other members of the EIF4F complex. A domain at its N-terminus can also interact with the poly(A)-binding protein, which may mediate the circularization of mRNA during translation. Alternative splicing results in multiple transcript variants, some of which are derived from alternative promoter usage. [provided by RefSeq, Aug 2010]
- Alternative Names
- EIF4G1; Eukaryotic translation initiation factor 4 gamma 1; P220; EIF4F; EIF4G; EIF4GI; PARK18; EIF-4G1
- Gene ID
- 1981
- UniProt ID
- Q04637
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See other products for "EIF4G1"
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1377MZ | Recombinant Mouse Anti-Human EIF4G1 Antibody | WB | Mouse antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHC-LC2090 | PE-B*07:02/Human EIF4G1 (AARPATSTL) MHC Tetramer | FCM |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-XY754 | Anti-EIF4G1 Immunohistochemistry Kit | IHC | |
| VS-0525-XY2233 | Anti-Mouse EIF4G1 Immunohistochemistry Kit | IHC |
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