PE-B*07:02/Human Tyrosinase (LPWHRLFLL) MHC Tetramer (CAT#: MHC-LC015)
This product is a tetramer of biotinylated peptide/MHC complex with streptavidin mainly composed of Tyrosinase-derived peptide of LPWHRLFLL sequence covering 208-216 and B*07:02 molecule. The pMHC tetramer recognizes human CD8 T cells, and can be used in the analysis of individual antigen-specific T cells.
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Custom Production
MHC tetramer custom production provides a vital tool for researchers seeking to understand and manipulate T-cell immunity with exceptional precision. Please specify your requirements, including peptide sequence, MHC allele, and desired fluorophore etc. We will respond as soon as possible with a tailored solution.
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Subcellular Location and Protein Expression
RNA Expression
Figure 1 IF staining of human cell line SK-MEL-30
(Immunofluorescent staining of human cell line SK-MEL-30 shows localization to vesicles.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/43241/1291_D5_4_selected.jpg
(Immunofluorescent staining of human cell line SK-MEL-30 shows localization to vesicles.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/43241/1291_D5_4_selected.jpg
Figure 2 RNA cell line category: Cell line enriched (SK-MEL-30)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000077498-TYR/subcellular
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000077498-TYR/subcellular
Specifications
- Allele
- B*07:02
- Class
- Class I
- MHC Species
- Human
- Antigen
- Tyrosinase
- Antigen Species
- Human
- Peptide
- LPWHRLFLL
- Range
- 208-216
- Conjugate
- PE
- Application
- FCM
Target
- Antigen Introduction
- The enzyme encoded by this gene catalyzes the first 2 steps, and at least 1 subsequent step, in the conversion of tyrosine to melanin. The enzyme has both tyrosine hydroxylase and dopa oxidase catalytic activities, and requires copper for function. Mutations in this gene result in oculocutaneous albinism, and nonpathologic polymorphisms result in skin pigmentation variation. The human genome contains a pseudogene similar to the 3' half of this gene.
- Alternative Names
- TYR; Tyrosinase; ATN; CMM8; OCA1; OCA1A; OCAIA; SHEP3
- Gene ID
- 7299
- UniProt ID
- P14679
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IgM Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1019 | Recombinant Anti-Tyr Antibody | ELISA, WB, IP, FuncS | IgG |
| MHH-1019 | Recombinant Human Anti-Tyr Antibody | RIA, IF, FuncS | IgG |
| MRO-1543-CN | Mouse Anti-TYR Recombinant Antibody (clone C2-B5) | WB, IF, IHC, FC | Mouse IgG1 |
| MRO-1544-CN | Rabbit Anti-TYR Recombinant Antibody (clone JA52-11) | WB, IF, IHC | Rabbit IgG |
| ZG-0616U | Rabbit Anti-TYR Recombinant Antibody (clone 6B2) | ELISA, IF | Rabbit IgG |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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