Mouse Anti-TYR Recombinant Antibody (VS3-CJ655)
CAT#: VS3-CJ655
This product is a mouse antibody that recognizes human TYR.
Gene Expression
Subcellular Location and Protein Expression
Figure 1 IF staining of human cell line SK-MEL-30
Immunofluorescent staining of human cell line SK-MEL-30 shows localization to vesicles.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/43241/1291_D5_4_selected.jpg
RNA Expression
Figure 2 RNA cell line category: Cell line enriched (SK-MEL-30)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000077498-TYR/subcellular
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Specifications
- Immunogen
- KLH-conjugated synthetic peptide encompassing a sequence within human Tyrosinase
- Host Species
- Mouse
- Type
- Mouse IgM
- Specificity
- Human TYR
- Species Reactivity
- Human
- Applications
- IHC
- Conjugate
- Unconjugated
Product Property
- Purification
- Immunogen affinity chromatography
- Purity
- >95% as determined by SDS-PAGE
- Format
- Liquid
- Buffer
- 50% Glycerol, 0.2% BSA, PBS.
- Preservative
- 0.01% Sodium Azide
- Storage
- Store at 4°C for short term. Aliquot and store at -20°C for long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Shipped at 4°C
Applications
- Application Notes
- This antibody has been tested for use in Immunohistochemistry (1:100-1:300).
Target
- Alternative Names
- ATN; CMM8; OCA1; OCA1A; OCAIA; SHEP3
- Gene ID
- 7299
- UniProt ID
- P14679
- Sequence Similarities
- Belongs to the tyrosinase family.
- Cellular Localization
- Membrane
- Post Translation Modifications
- Glycosylated.
- Protein Refseq
- NP_000363.1
- Function
- This is a copper-containing oxidase that functions in the formation of pigments such as melanins and other polyphenolic compounds (By similarity).
Catalyzes the initial and rate limiting step in the cascade of reactions leading to melanin production from tyrosine (By similarity).
In addition to hydroxylating tyrosine to DOPA (3,4-dihydroxyphenylalanine), also catalyzes the oxidation of DOPA to DOPA-quinone, and possibly the oxidation of DHI (5,6-dihydroxyindole) to indole-5,6 quinone (By similarity).
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Downloadable Resources
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Protocol & Troubleshooting
We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.
Secondary Antibody
- CAT
- Product Name
Recommended Dilution Buffer
- CAT
- Product Name
See other products for "Tyr"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1019 | Recombinant Anti-Tyr Antibody | ELISA, WB, IP, FuncS | IgG |
| MOB-0343MZ | Recombinant Mouse Anti-Human TYR Antibody (clone U312) | IHC | Mouse antibody |
| MRO-2248-CN | Rabbit Anti-TYR Polyclonal Antibody (MRO-2248-CN) | WB, IF, IHC, FC | Rabbit IgG |
| VS3-FY1502 | Recombinant Mouse Anti-TYR Antibody (clone 8H8-6G5-6H3) | IHC-P | Mouse IgA |
| VS13-YC1194 | Rabbit Anti-TYR Recombinant Antibody (VS13-YC1194) | WB, IHC-P, ICC, IF | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1019-F(E) | Recombinant Anti-Tyr Antibody Fab Fragment | RIA, WB, FuncS | Fab |
| MHH-1019-F(E) | Recombinant Human Anti-Tyr Antibody Fab Fragment | ELISA, WB, FC, FuncS | Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1019-S(P) | Recombinant Anti-Tyr Antibody scFv Fragment | ELISA, IF, FuncS | scFv |
| MHH-1019-S(P) | Recombinant Human Anti-Tyr Antibody scFv Fragment | WB, Neut, FuncS | scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-3734 | Rabbit Anti-TYR Recombinant Antibody (clone DS3734AB) | IHC-P, WB, ICC, IF | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY7664 | Anti-TYR Immunohistochemistry Kit | IHC | |
| VS-0525-XY7665 | Anti-Mouse TYR Immunohistochemistry Kit | IHC |
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