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Tyr

Anti-Tyr Products
- Mouse Anti-TYR Recombinant Antibody (VS3-CJ655) (VS3-CJ655)
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- Species Reactivity: Human
- Type: Mouse IgM
- Application: IHC
- Recombinant Human Anti-Tyrosinase Soluble TCR (KIH) (VS-0622-YF5878) (VS-0622-YF5878)
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- Species Reactivity: Human
- Epitope: YMDGTMSQV
- MHC: HLA-A*0201
- Recombinant Human Anti-Tyrosinase Soluble TCR (T43) (KIH) (VS-0622-YF5877)
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- Species Reactivity: Human
- Epitope: YMDGTMSQV
- MHC: HLA-A*0201
- Recombinant Human Anti-Tyrosinase Soluble TCR (di111) (KIH) (VS-0622-YF5876)
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- Species Reactivity: Human
- Epitope: YMDGTMSQV
- MHC: HLA-A*0201
- Recombinant Human Anti-Tyrosinase Soluble TCR (B12) (KIH) (VS-0622-YF5875)
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- Species Reactivity: Human
- Epitope: YMDGTMSQV
- MHC: HLA-A*0201
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- Species Reactivity: Human
- Epitope: YMDGTMSQV
- MHC: HLA-A*0201
- Recombinant Human Anti-Tyrosinase Soluble TCR (T43) (C-Cys) (VS-0622-YF3169)
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- Species Reactivity: Human
- Epitope: YMDGTMSQV
- MHC: HLA-A*0201
- Recombinant Human Anti-Tyrosinase Soluble TCR (di111) (C-Cys) (VS-0622-YF3168)
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- Species Reactivity: Human
- Epitope: YMDGTMSQV
- MHC: HLA-A*0201
- Recombinant Human Anti-Tyrosinase Soluble TCR (B12) (C-Cys) (VS-0622-YF3167)
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- Species Reactivity: Human
- Epitope: YMDGTMSQV
- MHC: HLA-A*0201
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- Species Reactivity: Human
- Epitope: YMDGTMSQV
- MHC: HLA-A*0201
-
- Species Reactivity: Human
- Epitope: YMDGTMSQV
- MHC: HLA-A*0201
-
- Species Reactivity: Human
- Epitope: YMDGTMSQV
- MHC: HLA-A*0201
-
- Species Reactivity: Human
- Epitope: YMDGTMSQV
- MHC: HLA-A*0201
- Recombinant Human Anti-Tyrosinase Soluble TCR (scTCR-463CQ-S(P)) (scTCR-463CQ-S(P))
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- Species Reactivity: Human
- Epitope: YMDGTMSQV
- MHC: HLA-A*0201
- Recombinant Human Anti-Tyrosinase Soluble TCR (clone T43) (scTCR-462CQ-S(P))
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- Species Reactivity: Human
- Epitope: YMDGTMSQV
- MHC: HLA-A*0201
- Recombinant Human Anti-Tyrosinase Soluble TCR (clone di111) (scTCR-461CQ-S(P))
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- Species Reactivity: Human
- Epitope: YMDGTMSQV
- MHC: HLA-A*0201
- Recombinant Human Anti-Tyrosinase Soluble TCR (clone B12) (scTCR-460CQ-S(P))
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- Species Reactivity: Human
- Epitope: YMDGTMSQV
- MHC: HLA-A*0201
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- Class: Class I
- Antigen: Tyrosinase
- Antigen Species: Human
- Peptide: YMNGTMSQV
- Conjugate: Unlabeled, Biotin, R-PE, APC
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- Class: Class I
- Antigen: Tyrosinase
- Antigen Species: Human
- Peptide: FLPWHRLFLL
- Conjugate: Unlabeled, Biotin, R-PE, APC
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- Class: Class I
- Antigen: Tyrosinase
- Antigen Species: Human
- Peptide: AMVGAVLTA
- Conjugate: Unlabeled, Biotin, R-PE, APC
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- Class: Class I
- Antigen: Tyrosinase
- Antigen Species: Human
- Peptide: KCDICTDEY
- Conjugate: Unlabeled, Biotin, R-PE, APC
- A*01:01/Human Tyr A1a (DSDPDSFQDY) MHC Pentamer (MHC-YF761)
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- Class: Class I
- Antigen: Tyr A1a
- Antigen Species: Human
- Peptide: DSDPDSFQDY
- Conjugate: Unlabeled, Biotin, R-PE, APC
- A*02:01/Human Tyrosinase (YMDGTMSQV) MHC Monomer (MHC-YF230)
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- Class: Class I
- Antigen: Tyrosinase
- Antigen Species: Human
- Peptide: YMDGTMSQV
- Conjugate: Biotin
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- Class: Class II
- Antigen: tyrosinase
- Antigen Species: Human
- Peptide: ALHIYMDGTMSQVQGSA
- Conjugate: Biotin
- A*01:01/Human TYR (SSDYVIPIGTY) MHC Tetramer (MHC-CN1296)
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- Class: Class I
- Antigen: TYR
- Antigen Species: Human
- Peptide: SSDYVIPIGTY
- Conjugate: Unconjugated
- FITC-A*01:01/Human TYR (SSDYVIPIGTY) MHC Tetramer (MHC-CN1295)
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- Class: Class I
- Antigen: TYR
- Antigen Species: Human
- Peptide: SSDYVIPIGTY
- Conjugate: FITC
- APC-A*01:01/Human TYR (SSDYVIPIGTY) MHC Tetramer (MHC-CN1294)
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- Class: Class I
- Antigen: TYR
- Antigen Species: Human
- Peptide: SSDYVIPIGTY
- Conjugate: APC
- PE-A*01:01/Human TYR (SSDYVIPIGTY) MHC Tetramer (MHC-CN1293)
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- Class: Class I
- Antigen: TYR
- Antigen Species: Human
- Peptide: SSDYVIPIGTY
- Conjugate: PE
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- Class: Class II
- Antigen: TYR
- Antigen Species: Human
- Peptide: QNILLSNAPLGPQFP
- Conjugate: PE
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- Class: Class II
- Antigen: TYR
- Antigen Species: Human
- Peptide: NILLSNAPLGPQFP
- Conjugate: PE
- PE-A*02:01/Human TYR (YMNGTMSQV) MHC Tetramer (MHC-LC2230)
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- Class: Class I
- Antigen: TYR
- Antigen Species: Human
- Peptide: YMNGTMSQV
- Conjugate: PE
- PE-A*02:01/Human TYR (MLLAVLYCL) MHC Tetramer (MHC-LC2226)
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- Class: Class I
- Antigen: TYR
- Antigen Species: Human
- Peptide: MLLAVLYCL
- Conjugate: PE
- PE-B*35:01/Human TYR (LPWHRLFLL) MHC Tetramer (MHC-LC2514)
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- Class: Class I
- Antigen: TYR
- Antigen Species: Human
- Peptide: LPWHRLFLL
- Conjugate: PE
- PE-B*07:02/Human TYR (LPWHRLFLL) MHC Tetramer (MHC-LC2513)
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- Class: Class I
- Antigen: TYR
- Antigen Species: Human
- Peptide: LPWHRLFLL
- Conjugate: PE
- PE-B*07:02/Human TYR (IPLYRNGDF) MHC Tetramer (MHC-LC2482)
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- Class: Class I
- Antigen: TYR
- Antigen Species: Human
- Peptide: IPLYRNGDF
- Conjugate: PE
- PE-B*54:01/Human TYR (DPIFLLHHA) MHC Tetramer (MHC-LC2466)
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- Class: Class I
- Antigen: TYR
- Antigen Species: Human
- Peptide: DPIFLLHHA
- Conjugate: PE
- PE-B*51:01/Human TYR (DPIFLLHHA) MHC Tetramer (MHC-LC2465)
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- Class: Class I
- Antigen: TYR
- Antigen Species: Human
- Peptide: DPIFLLHHA
- Conjugate: PE
- PE-B*51:01/Human TYR (DPDSFQDYI) MHC Tetramer (MHC-LC2464)
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- Class: Class I
- Antigen: TYR
- Antigen Species: Human
- Peptide: DPDSFQDYI
- Conjugate: PE
- PE-B*53:01/Human TYR (SPASFFSSW) MHC Tetramer (MHC-LC2535)
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- Class: Class I
- Antigen: TYR
- Antigen Species: Human
- Peptide: SPASFFSSW
- Conjugate: PE
- PE-B*35:01/Human TYR (SPASFFSSW) MHC Tetramer (MHC-LC2534)
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- Class: Class I
- Antigen: TYR
- Antigen Species: Human
- Peptide: SPASFFSSW
- Conjugate: PE
- PE-B*07:02/Human TYR (SPASFFSSW) MHC Tetramer (MHC-LC2533)
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- Class: Class I
- Antigen: TYR
- Antigen Species: Human
- Peptide: SPASFFSSW
- Conjugate: PE
- PE-B*54:01/Human TYR (LPWHRLFLL) MHC Tetramer (MHC-LC2517)
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- Class: Class I
- Antigen: TYR
- Antigen Species: Human
- Peptide: LPWHRLFLL
- Conjugate: PE
- PE-B*53:01/Human TYR (LPWHRLFLL) MHC Tetramer (MHC-LC2516)
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- Class: Class I
- Antigen: TYR
- Antigen Species: Human
- Peptide: LPWHRLFLL
- Conjugate: PE
- PE-B*51:01/Human TYR (LPWHRLFLL) MHC Tetramer (MHC-LC2515)
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- Class: Class I
- Antigen: TYR
- Antigen Species: Human
- Peptide: LPWHRLFLL
- Conjugate: PE
- PE-A*02:01/Human TYR (ALLAGLVSL) MHC Tetramer (MHC-LC2901)
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- Class: Class I
- Antigen: TYR
- Antigen Species: Human
- Peptide: ALLAGLVSL
- Conjugate: PE
- APC-A*02:01/Human TYR (YMNGTMSQV) MHC Tetramer (MHC-LC2630)
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- Class: Class I
- Antigen: TYR
- Antigen Species: Human
- Peptide: YMNGTMSQV
- Conjugate: APC
- APC-A*02:01/Human TYR (MLLAVLYCL) MHC Tetramer (MHC-LC2626)
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- Class: Class I
- Antigen: TYR
- Antigen Species: Human
- Peptide: MLLAVLYCL
- Conjugate: APC
- PE-B*53:01/Human TYR (TPMFNDINI) MHC Tetramer (MHC-LC2550)
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- Class: Class I
- Antigen: TYR
- Antigen Species: Human
- Peptide: TPMFNDINI
- Conjugate: PE
- PE-B*51:01/Human TYR (TPMFNDINI) MHC Tetramer (MHC-LC2549)
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- Class: Class I
- Antigen: TYR
- Antigen Species: Human
- Peptide: TPMFNDINI
- Conjugate: PE
- PE-B*07:02/Human TYR (TPMFNDINI) MHC Tetramer (MHC-LC2548)
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- Class: Class I
- Antigen: TYR
- Antigen Species: Human
- Peptide: TPMFNDINI
- Conjugate: PE
- PE-A*02:01/Human TYR (LLAGLVSLL) MHC Tetramer (MHC-LC2919)
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- Class: Class I
- Antigen: TYR
- Antigen Species: Human
- Peptide: LLAGLVSLL
- Conjugate: PE
- PE-A*02:01/Human TYR (FLPWHRLFLL) MHC Tetramer (MHC-LC2911)
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- Class: Class I
- Antigen: TYR
- Antigen Species: Human
- Peptide: FLPWHRLFLL
- Conjugate: PE
- PE-A*02:01/Human TYR (FLPWHRLFL) MHC Tetramer (MHC-LC2910)
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- Class: Class I
- Antigen: TYR
- Antigen Species: Human
- Peptide: FLPWHRLFL
- Conjugate: PE
- PE-A*02:01/Human TYR (FLLRWEQEI) MHC Tetramer (MHC-LC2909)
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- Class: Class I
- Antigen: TYR
- Antigen Species: Human
- Peptide: FLLRWEQEI
- Conjugate: PE
- PE-A*02:01/Human TYR (AMVGAVLTA) MHC Tetramer (MHC-LC2905)
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- Class: Class I
- Antigen: TYR
- Antigen Species: Human
- Peptide: AMVGAVLTA
- Conjugate: PE
- PE-A*02:01/Human TYR (ALLAGLVSLL) MHC Tetramer (MHC-LC2902)
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- Class: Class I
- Antigen: TYR
- Antigen Species: Human
- Peptide: ALLAGLVSLL
- Conjugate: PE
- PE-Mamu-A1*011:01/Human TYR (SEIWRDIDF) MHC Tetramer (MHC-LC3000)
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- Class: Class I
- Antigen: TYR
- Antigen Species: Human
- Peptide: SEIWRDIDF
- Conjugate: PE
- PE-A*02:01/Human TYR (WLLGAAMVGA) MHC Tetramer (MHC-LC2939)
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- Class: Class I
- Antigen: TYR
- Antigen Species: Human
- Peptide: WLLGAAMVGA
- Conjugate: PE
- PE-A*02:01/Human TYR (VLTALLAGL) MHC Tetramer (MHC-LC2936)
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- Class: Class I
- Antigen: TYR
- Antigen Species: Human
- Peptide: VLTALLAGL
- Conjugate: PE
- PE-A*02:01/Human TYR (RIWSWLLGA) MHC Tetramer (MHC-LC2927)
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- Class: Class I
- Antigen: TYR
- Antigen Species: Human
- Peptide: RIWSWLLGA
- Conjugate: PE
- PE-A*02:01/Human TYR (LLWSFQTSA) MHC Tetramer (MHC-LC2922)
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- Class: Class I
- Antigen: TYR
- Antigen Species: Human
- Peptide: LLWSFQTSA
- Conjugate: PE
- PE-A*02:01/Human TYR (LLAVLYCLL) MHC Tetramer (MHC-LC2920)
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- Class: Class I
- Antigen: TYR
- Antigen Species: Human
- Peptide: LLAVLYCLL
- Conjugate: PE
- PE-A*03:01/Human TYR (YMVPFIPLYR) MHC Tetramer (MHC-LC3031)
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- Class: Class I
- Antigen: TYR
- Antigen Species: Human
- Peptide: YMVPFIPLYR
- Conjugate: PE
- PE-A*11:01/Human TYR (SIFEQWLRR) MHC Tetramer (MHC-LC3025)
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- Class: Class I
- Antigen: TYR
- Antigen Species: Human
- Peptide: SIFEQWLRR
- Conjugate: PE
- PE-A*03:01/Human TYR (SIFEQWLRR) MHC Tetramer (MHC-LC3024)
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- Class: Class I
- Antigen: TYR
- Antigen Species: Human
- Peptide: SIFEQWLRR
- Conjugate: PE
- PE-A*11:01/Human TYR (QTSAGHFPR) MHC Tetramer (MHC-LC3023)
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- Class: Class I
- Antigen: TYR
- Antigen Species: Human
- Peptide: QTSAGHFPR
- Conjugate: PE
- APC-B*07:02/Human TYR (LPWHRLFLL) MHC Tetramer (MHC-LC3017)
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- Class: Class I
- Antigen: TYR
- Antigen Species: Human
- Peptide: LPWHRLFLL
- Conjugate: APC
- PE-B*07:02/Human TYR (IPIGTYGQM) MHC Tetramer (MHC-LC3012)
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- Class: Class I
- Antigen: TYR
- Antigen Species: Human
- Peptide: IPIGTYGQM
- Conjugate: PE
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- Class: Class II
- Antigen: TYR
- Antigen Species: Human
- Peptide: DYSYLQDSDPDSFQD
- Conjugate: PE
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- Class: Class II
- Antigen: TYR
- Antigen Species: Human
- Peptide: ALHIYMNGTMSQVQGSA
- Conjugate: PE
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- Class: Class II
- Antigen: TYR
- Antigen Species: Human
- Peptide: ALHIYMNGTMSQVQGSA
- Conjugate: PE
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- Class: Class II
- Antigen: TYR
- Antigen Species: Human
- Peptide: ALHIYMDGTMSQVQGSA
- Conjugate: PE
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- Class: Class II
- Antigen: TYR
- Antigen Species: Human
- Peptide: ALHIYMDGTMSQVQGSA
- Conjugate: PE
- PE-A*11:01/Human TYR (YMVPFIPLYR) MHC Tetramer (MHC-LC3032)
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- Class: Class I
- Antigen: TYR
- Antigen Species: Human
- Peptide: YMVPFIPLYR
- Conjugate: PE
- PE-A*01:01/Human TYR (KCDICTDEY) MHC Tetramer (MHC-LC4411)
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- Class: Class I
- Antigen: TYR
- Antigen Species: Human
- Peptide: KCDICTDEY
- Conjugate: PE
- PE-A*24:02/Human TYR (AFLPWHRLF) MHC Tetramer (MHC-LC3294)
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- Class: Class I
- Antigen: TYR
- Antigen Species: Human
- Peptide: AFLPWHRLF
- Conjugate: PE
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- Class: Class II
- Antigen: TYR
- Antigen Species: Human
- Peptide: YGQMKNGSTPMFNDINIYDL
- Conjugate: PE
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- Class: Class II
- Antigen: TYR
- Antigen Species: Human
- Peptide: YGQMKNGSTPMFNDINIYDL
- Conjugate: PE
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- Class: Class II
- Antigen: TYR
- Antigen Species: Human
- Peptide: QNILLSNAPLGPQFP
- Conjugate: PE
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- Class: Class II
- Antigen: TYR
- Antigen Species: Human
- Peptide: QNILLSNAPLGPQFP
- Conjugate: APC
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- Class: Class I
- Antigen: Tyrosinase precursor
- Antigen Species: Human
- Peptide: KLTGDENFTI
- Conjugate: Unlabeled, Biotin, R-PE, APC
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- Class: Class I
- Antigen: Tyrosinase (371D)
- Antigen Species: Human
- Peptide: YMDGTMSQV
- Conjugate: Unlabeled, Biotin, R-PE, APC
-
- Class: Class I
- Antigen: Tyrosinase
- Antigen Species: Human
- Peptide: LPWHRLFLL
- Conjugate: Unlabeled, Biotin, R-PE, APC
-
- Class: Class I
- Antigen: Tyrosinase
- Antigen Species: Human
- Peptide: AFLPWHRLF
- Conjugate: Unlabeled, Biotin, R-PE, APC
- Recombinant Anti-Tyr Antibody (MOB-1019)
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- Derivation: Mouse
- Type: IgG
- Application: ELISA, WB, IP, FuncS
- Recombinant Human Anti-Tyr Antibody (MHH-1019)
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- Derivation: Human
- Type: IgG
- Application: RIA, IF, FuncS
- Rabbit Anti-TYR Recombinant Antibody (clone JA52-11) (MRO-1544-CN)
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- Species Reactivity: Human
- Type: Rabbit IgG
- Application: WB, IF, IHC
- Mouse Anti-TYR Recombinant Antibody (clone C2-B5) (MRO-1543-CN)
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- Species Reactivity: Human, Mouse
- Type: Mouse IgG1
- Application: WB, IF, IHC, FC
- Rabbit Anti-TYR Polyclonal Antibody (MRO-2248-CN) (MRO-2248-CN)
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- Species Reactivity: Human, Mouse
- Type: Rabbit IgG
- Application: WB, IF, IHC, FC
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- Species Reactivity: Human, Mouse
- Type: Mouse IgG
- Application: IHC-P, IF
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- Species Reactivity: Human, Mouse
- Type: Mouse IgG
- Application: IHC-P, IF
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- Species Reactivity: Human
- Type: Rabbit IgG
- Application: ELISA, IF
-
- Species Reactivity: Human
- Type: Mouse IgA
- Application: IHC-P
- Recombinant Human Anti-Tyr Antibody scFv Fragment (MHH-1019-S(P))
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- Derivation: Human
- Type: scFv
- Application: WB, Neut, FuncS
- Recombinant Anti-Tyr Antibody scFv Fragment (MOB-1019-S(P))
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- Derivation: Mouse
- Type: scFv
- Application: ELISA, IF, FuncS
- Recombinant Anti-Tyr Antibody Fab Fragment (MOB-1019-F(E))
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- Derivation: Mouse
- Type: Fab
- Application: RIA, WB, FuncS
- Recombinant Human Anti-Tyr Antibody Fab Fragment (MHH-1019-F(E))
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- Derivation: Human
- Type: Fab
- Application: ELISA, WB, FC, FuncS
- Anti-Mouse TYR Immunohistochemistry Kit (VS-0525-XY7665)
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- Species Reactivity: Human, Mouse
- Target: TYR
- Application: IHC
- Anti-TYR Immunohistochemistry Kit (VS-0525-XY7664)
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- Species Reactivity: Human
- Target: TYR
- Application: IHC
- Rabbit Anti-TYR Recombinant Antibody (VS13-YC1194) (VS13-YC1194)
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- Species Reactivity: Human
- Type: Rabbit IgG
- Application: WB, IHC-P, ICC, IF
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For Research Use Only. Not For Clinical Use.
The enzyme encoded by this gene catalyzes the first 2 steps, and at least 1 subsequent step, in the conversion of tyrosine to melanin. The enzyme has both tyrosine hydroxylase and dopa oxidase catalytic activities, and requires copper for function. Mutations in this gene result in oculocutaneous albinism, and nonpathologic polymorphisms result in skin pigmentation variation. The human genome contains a pseudogene similar to the 3' half of this gene. [provided by RefSeq, Oct 2008]
Protein class
Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins
Predicted location
Membrane
Single cell type specificity
Cell type enriched (Melanocytes)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Cell line enriched (SK-MEL-30)
Interaction
Forms an OPN3-dependent complex with DCT in response to blue light in melanocytes.
Molecular function
Monooxygenase, Oxidoreductase, Tumor antigen
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