PE-DRB1*15:01/Human MHC I (EAEQLRAYLDGTGVE) MHC Tetramer
CAT#: MHC-LC3351
This product is a tetramer of biotinylated peptide/MHC complex with streptavidin mainly composed of human MHC I of peptide EAEQLRAYLDGTGVE and DRB1*15:01 molecule. The pMHC tetramer recognizes CD4 T cells, and can be used in the analysis of individual antigen-specific T cells.
Specifications
- Allele
- DRB1*15:01
- Class
- Class II
- MHC Species
- Human
- Antigen
- MHC I
- Antigen Species
- Human
- Peptide
- EAEQLRAYLDGTGVE
- Conjugate
- PE
- Application
- FCM
Target
- Antigen Introduction
- MHC class I molecules are one of two primary classes of major histocompatibility complex (MHC) molecules (the other being MHC class II) and are found on the cell surface of all nucleated cells in the bodies of jawed vertebrates. They also occur on platelets, but not on red blood cells. Their function is to display peptide fragments of non-self proteins from within the cell to cytotoxic T cells; this will trigger an immediate response from the immune system against a particular non-self antigen displayed with the help of an MHC class I protein. Because MHC class I molecules present peptides derived from cytosolic proteins, the pathway of MHC class I presentation is often called cytosolic or endogenous pathway.
- Alternative Names
- MHC I; Class I MHC; MHC class I antigen
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