Recombinant Anti-Human NPHS1 Antibody Fab Fragment (CAT#: MOB-1833z-F(E))
Recombinant Mouse Antibody Fab Fragment is against Human NPHS1, expressed in Chinese Hamster Ovary cells(CHO).
Specific Inquiry
Custom Production
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
We require custom production
Normal Tissue
RNA Expression
Figure 1 Cerebral cortex
(Endothelial cells Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous Neuronal cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Nuclear Neuropil Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/35555/67641_B_8_5.jpg
(Endothelial cells Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous Neuronal cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Nuclear Neuropil Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/35555/67641_B_8_5.jpg
Figure 2 Colon
(Endothelial cells Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous Glandular cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Peripheral nerve/ganglion Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/35555/67641_A_9_3.jpg
(Endothelial cells Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous Glandular cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Peripheral nerve/ganglion Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/35555/67641_A_9_3.jpg
Figure 3 High expression in kidney.
(Cells in glomeruli Staining: High Intensity: Strong Quantity: 75%-25% Distal tubules Staining: Low Intensity: Weak Quantity:>75%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/35555/67641_A_9_5.jpg
(Cells in glomeruli Staining: High Intensity: Strong Quantity: 75%-25% Distal tubules Staining: Low Intensity: Weak Quantity:>75%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/35555/67641_A_9_5.jpg
Figure 4 Testis
(Cells in seminiferous ducts Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Leydig cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/35555/67641_A_4_6.jpg
(Cells in seminiferous ducts Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Leydig cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/35555/67641_A_4_6.jpg
Figure 5 Lymph node
(Germinal center cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/35555/67641_A_9_8.jpg
(Germinal center cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/35555/67641_A_9_8.jpg
Figure 6 RNA cell line category: Cell line enhanced (HMC-1, JURKAT)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000161270-NPHS1
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000161270-NPHS1
Specifications
- Immunogen
- Human Nephrosis 1, Congenital, Finnish Type (Nephrin)
- Host Species
- Mouse
- Derivation
- Mouse
- Type
- Fab
- Specificity
- Tested positive against native Human Nephrosis 1, Congenital, Finnish Type (Nephrin)
- Species Reactivity
- Human
- Applications
- Can be useful in applications such as: Immunofluorescence; Neutralization; Functional Study
Product Property
- Purity
- >95% as determined by analysis by SDS-PAGE
- Storage
- 4°C or -20°C, avoid repeated freezing and thawing.
Target
- Alternative Names
- NPHS1; NPHN; Renal Glomerulus-Specific Cell Adhesion Receptor; CNF; Nephrin; Nephrosis 1, Congenital, Finnish Type (Nephrin)
- Gene ID
- 4868
- UniProt ID
- O60500
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "NPHS1"
Select a product category from the dropdown menu below to view related products.
Please select product type
ScFv Antibody Products
Rabbit Monoclonal Antibody Products
IgG Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1833z-S(P) | Recombinant Anti-Human NPHS1 Antibody scFv Fragment | WB, Neut, FuncS | scFv |
Customer Reviews and Q&As
Customer Review
Q&As
Focused Kidney Research Utility
The Anti-Human NPHS1 Fab Fragment has been a key tool in our kidney research. Its ability to target nephrin specifically helps us shed light on its role in podocyte function and integrity, which is crucial for our studies into nephrotic syndrome mechanisms.
Exemplary for Glomerular Studies
This Fab fragment has been exemplary in our glomerular research, allowing us to zero in on nephrin's role in maintaining filtration barrier function. The crisp results in our immunofluorescence assays have highlighted differences between healthy and diseased states, aiding our understanding of glomerular pathologies.
Superior Tissue Penetration
The Fab fragment's small size allows it to penetrate tissues more effectively than full-sized antibodies, giving us enhanced resolution in heavily structured areas within our kidney tissue studies.
Popular products with customers
Application: FC, IP, ELISA, Neut, FuncS, IF, IHC
Application: ELISA, IP, FC, FuncS, Neut, IF, WB
Application: IF, IP, Neut, FuncS, ELISA, FC, ICC
Application: ELISA, Neut, IF, IP, FC, FuncS
Application: IP, IF, FuncS, FC, Neut, ELISA, ICC
Application: ELISA, IHC
Application: IF, IP, Neut, FuncS, ELISA, FC, ICC
Application: ELISA, IHC, FC, IP, IF, BL
For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
Send Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
