Recombinant Anti-Human CTGF Antibody (Fc glycosylation) (CAT#: Gly-119LC)
This product is a human monoclonal antibody with glycoyslation site at in Fc region. The antibody mAb1 with enhanced ADCC specficfically binds to human CTGF and can be potentially used in the treatment of cardiovascular disease.
Specific Inquiry
Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line U-2 OS
(Immunofluorescent staining of human cell line U-2 OS shows localization to the Golgi apparatus & vesicles.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/31074/564_D9_2_selected.jpg
(Immunofluorescent staining of human cell line U-2 OS shows localization to the Golgi apparatus & vesicles.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/31074/564_D9_2_selected.jpg
Figure 2 IHC staining of human stomach, upper
(Immunohistochemical staining of human stomach, upper shows moderate positivity in plasma and stromal cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/31075/ihc_selected.jpg
(Immunohistochemical staining of human stomach, upper shows moderate positivity in plasma and stromal cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/31075/ihc_selected.jpg
Figure 3 Lymph node
(Non-germinal center cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/5123/15554_A_9_8.jpg
(Non-germinal center cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/5123/15554_A_9_8.jpg
Figure 4 Cerebral cortex
(Neuronal cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/5123/15554_B_7_5.jpg
(Neuronal cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/5123/15554_B_7_5.jpg
Figure 5 Liver
(Hepatocytes Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/5123/15554_A_8_4.jpg
(Hepatocytes Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/5123/15554_A_8_4.jpg
Figure 6 Smooth muscle
(Smooth muscle cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/5123/15554_B_5_7.jpg
(Smooth muscle cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/5123/15554_B_5_7.jpg
Figure 7 RNA cell line category: Cell line enhanced (EFO-21, HUVEC TERT2, TIME)
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000118523-CTGF
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000118523-CTGF
Glyco-engineering
- Glycosylation site
- Fc region
- Glycosylation Type
- N-glycosylation
- Activity
- Enhanced ADCC
Specifications
- Target
- CTGF (Connective tissue growth factor)
- Host Species
- Human
- Derivation
- 8C12-F10 cell line
- Type
- Human antibody
- Specificity
- Human
- Clone
- mAb1
- Applications
- ELISA
Target
- Alternative Names
- CTGF; connective tissue growth factor; CCN2; NOV2; HCS24; IGFBP8; IBP-8; IGFBP-8; CCN family member 2; IGF-binding protein 8; hypertrophic chondrocyte-specific protein 24; insulin-like growth factor-binding protein 8
- Related Disease
- Cardiovascular disease
- Gene ID
- 1490
- UniProt ID
- P29279
Downloads
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IgG Antibody Products
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IHC Kit and Antibody Products: Precision Tools for Immunohistochemistry
ScFv-Fc Chimera Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1576z | Mouse Anti-CTGF Recombinant Antibody (clone 32G9) | ELISA, IHC | Mouse IgG1 |
| HPAB-0181-YC | Human Anti-CTGF Recombinant Antibody (HPAB-0181-YC) | ELISA, FuncS | Human IgG |
| MRO-1793-CN | Rabbit Anti-CTGF Polyclonal Antibody (MRO-1793-CN) | WB, IF, IHC | Rabbit IgG |
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