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    Afuco™ Anti-CTGF ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-443CQ) (CAT#: AFC-TAB-443CQ)

    This product is an ADCC enhanced antibody produced by our Afuco™ platform. Recombinant monoclonal antibody to CTGF. It is a human monoclonal antibody that can be potentially used in the treatment of Duchenne muscular dystrophy, Hepatic fibrosis, Idiopathic pulmonary fibrosis, Pancreatic cancer. It inhibits connective tissue growth factor (CTGF).

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    Custom Production

    We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.

    Sequences:
    Isotype :
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    Other Requirements:
    We require custom production
    • Gene Expression
    • Datasheet
    • MSDS
    • COA
    Subcellular Location
    Figure 1 IF staining of human cell line U-2 OS
    Figure 1 IF staining of human cell line U-2 OS
    (Immunofluorescent staining of human cell line U-2 OS shows localization to the Golgi apparatus & vesicles.)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/31074/564_D9_2_selected.jpg
    Normal Tissue
    Figure 2 IHC staining of human stomach, upper
    Figure 2 IHC staining of human stomach, upper
    (Immunohistochemical staining of human stomach, upper shows moderate positivity in plasma and stromal cells.)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/31075/ihc_selected.jpg
    Figure 3 Lymph node
    Figure 3 Lymph node
    (Non-germinal center cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/5123/15554_A_9_8.jpg
    Figure 4 Cerebral cortex
    Figure 4 Cerebral cortex
    (Neuronal cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/5123/15554_B_7_5.jpg
    Figure 5 Liver
    Figure 5 Liver
    (Hepatocytes Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/5123/15554_A_8_4.jpg
    Figure 6 Smooth muscle
    Figure 6 Smooth muscle
    (Smooth muscle cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/5123/15554_B_5_7.jpg
    RNA Expression
    Figure 7 RNA cell line category: Cell line enhanced (EFO-21, HUVEC TERT2, TIME)
    Figure 7 RNA cell line category: Cell line enhanced (EFO-21, HUVEC TERT2, TIME)
    (Cell lines ordered by descending RNA expression order)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000118523-CTGF

    Specifications

    • Immunogen
    • The details of the immunogen for this antibody are not available.
    • Host Species
    • Human
    • Derivation
    • Human
    • Type
    • ADCC enhanced antibody
    • Specificity
    • Human CTGF
    • Species Reactivity
    • Human
    • Applications
    • ELISA, IHC, FC, IP, IF, Inhib
    • Conjugate
    • Unconjugated
    • Generic Name
    • Pamrevlumab
    • Related Disease
    • Duchenne muscular dystrophy, Hepatic fibrosis, Idiopathic pulmonary fibrosis, Pancreatic cancer

    Product Property

    • Purity
    • >95% by SDS-PAGE
    • Storage
    • Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

    Target

    • Alternative Names
    • CTGF; connective tissue growth factor; CCN2; NOV2; HCS24; IGFBP8; IBP-8; IGFBP-8; CCN family member 2; IGF-binding protein 8; hypertrophic chondrocyte-specific protein 24; insulin-like growth factor-binding protein 8

    Product Notes

    This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

    • Increased sensitivity
    • Confirmed specificity
    • High repeatability
    • Excellent batch-to-batch consistency
    • Sustainable supply
    • Animal-free production

    See more details about Hi-Affi™ recombinant antibody benefits.

    Downloads

    Download resources about recombinant antibody development and antibody engineering to boost your research.

    See other products for "CTGF"

    Select a product category from the dropdown menu below to view related products.
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    IgG Antibody Products Human Antibody Products Mouse Antibody Products Fc Glycosylation Antibody Products ScFv Antibody Products Fab Antibody Products IHC Kit and Antibody Products: Precision Tools for Immunohistochemistry ScFv-Fc Chimera Products
    CAT Product Name Application Type
    MOB-1576z Mouse Anti-CTGF Recombinant Antibody (clone 32G9) ELISA, IHC Mouse IgG1
    HPAB-0181-YC Human Anti-CTGF Recombinant Antibody (HPAB-0181-YC) ELISA, FuncS Human IgG
    MRO-1793-CN Rabbit Anti-CTGF Polyclonal Antibody (MRO-1793-CN) WB, IF, IHC Rabbit IgG

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    For Research Use Only. Not For Clinical Use.

    For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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