Recombinant Human Anti-Human KDM4A Antibody Fab Fragment, clone D266
CAT#: DrMAB-366
Recombinant Human Antibody binds selectively to Human KDM4A, expressed in E. coli.
Gene Expression
Subcellular Location and Protein Expression
Figure 1 IF staining of human cell line U-2 OS
Immunofluorescent staining of human cell line U-2 OS shows localization to nucleoli fibrillar center.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/7610/if_selected.jpg
Subcellular Location and Protein Expression
Figure 2 IHC staining of human testis
Immunohistochemical staining of human testis shows strong cytoplasmic positivity in cells in seminiferus ducts.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/7610/ihc_selected.jpg
Subcellular Location and Protein Expression
Figure 3 IF staining of human cell line A-431
Immunofluorescent staining of human cell line A-431 shows localization to nucleoli fibrillar center.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/7610/75_D3_1_blue_red_green.jpg
Subcellular Location and Protein Expression
Figure 4 IF staining of human cell line U-251 MG
Immunofluorescent staining of human cell line U-251 MG shows localization to nucleoli fibrillar center.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/7610/74_D3_1_blue_red_green.jpg
Normal Tissue
Figure 5 Cerebral cortex
Neuronal cells
Staining:High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous nuclear
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/7610/21324_B_7_5.jpg
Normal Tissue
Figure 6 Testis
Cells in seminiferous ducts
Staining:High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/7610/21324_A_4_6.jpg
RNA Expression
Figure 7 RNA cell line category: Low cell line specificity
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000066135-KDM4A
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Specifications
- Immunogen
- The details of the immunogen for this antibody are not available.
- Host Species
- Human
- Type
- Fab
- Specificity
- reacts with human KDM4A
- Species Reactivity
- Human
- Clone
- D266
- Applications
- IP; IF; ELISA; IP-MS
Product Property
- Storage
- short term – store at 4°C (over 6 months), long term - PBS -20°C or -80°C
Target
- Alternative Names
- KDM4A; lysine (K)-specific demethylase 4A; JMJD2; JHDM3A; JMJD2A; TDRD14A; lysine-specific demethylase 4A; jmjC domain-containing histone demethylation protein 3A; jumonji C domain-containing histone demethylase 3A; jumonji domain containing 2; jumonji do
- Gene ID
- 9682
- UniProt ID
- O75164
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Easy to Use
As a Fab fragment, this antibody is straightforward to incorporate into our assays. It's compatible with various applications, and we've had success in both ELISA and immunoprecipitation experiments.
Valuable in Cancer Research
Studying the role of KDM4A in cancer cells has been enriched by using this antibody. It helps us understand the epigenetic mechanisms at play, contributing valuable insights into our oncology projects.
Suitable for Multiple Assays
We've successfully used this antibody in different types of assays, including IP, IF, and ELISA. Its versatility makes it a staple in our laboratory.
Q&As
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What is the main target of this antibody?
A: This antibody specifically targets human KDM4A, a lysine-specific demethylase 4A involved in epigenetic regulation. KDM4A plays a key role in modifying histones, which can influence gene expression in various biological processes.
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What applications is this antibody suitable for?
A: It is suitable for applications like immunoprecipitation and ELISA. Researchers use it to detect and quantify KDM4A protein levels in different sample types.
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Does this antibody recognize KDM4A in other species?
A: This antibody is specific for human KDM4A. Cross-reactivity with KDM4A from other species has not been confirmed, so it's primarily recommended for human protein studies.
View the frequently asked questions answered by Creative Biolabs Support.
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Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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Protocol & Troubleshooting
We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.
See other products for "KDM4A"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1431MZ | Recombinant Mouse Anti-Human KDM4A Antibody (clone 6I2) | ELISA, ICC, IF, IHC-P, WB | Mouse antibody |
| VS3-WK56 | Mouse Anti-KDM4A Recombinant Antibody (clone E7-H1) | WB, ELISA | Mouse IgG1 |
| VS3-XY963 | Mouse Anti-KDM4A Recombinant Antibody (clone 5H1) | ELISA, WB, IHC, ICC | Mouse IgG1 |
| VS3-FY791 | Recombinant Rabbit Anti-KDM4A Antibody (clone R01-7F2) | WB, IP | Rabbit IgG |
| VS7-0425-WR200 | Mouse Anti-KDM4A Recombinant Antibody (clone 6E10G4) | ICC, FC | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY3752 | Anti-KDM4A Immunohistochemistry Kit | IHC |
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