Recombinant Human Anti-human COMT Antibody
CAT#: MHH-231
Recombinant Human Antibody is directed against Human COMT, expressed in HEK 293 cells. Expressed as the combination of a heavy chain (HC) containing VH from anti-COMT mAb and CH1-3 region of human IgG1 and a light chain (LC) encoding VL from anti-COMT mAb and CL of human kappa light chain. Exists as a disulfide linked dimer of the HC and LC hetero-dimer under non-reducing condition.
Gene Expression
Normal Tissue
Figure 1 Colon
Glandular cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/11233/26804_A_7_3.jpg
Normal Tissue
Figure 2 Liver
Hepatocytes
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/11233/26804_A_9_4.jpg
Normal Tissue
Figure 3 Kidney
Bowman's capsule
Staining: Medium
Intensity: Moderate
Quantity:>75%
Cells in glomeruli
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Collecting ducts
Staining: High
Intensity: Strong
Quantity: 75%-25%
Distal tubules
Staining: High
Intensity: Strong
Quantity:>75%
Proximal tubules (cell body)
Staining: Medium
Intensity: Strong
Quantity: <25%
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/11233/26804_A_8_5.jpg
Normal Tissue
Figure 4 Testis
Leydig cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Sertoli cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/11233/26804_A_6_6.jpg
Normal Tissue
Figure 5 Placenta
Cytotrophoblasts
Staining: High
Intensity: Strong
Quantity:>75%
Endothelial cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Hofbauer cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Syncytiotrophoblasts - cell body
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Syncytiotrophoblasts - microvilli
Staining: Medium
Intensity: Moderate
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/11233/26804_A_2_7.jpg
RNA Expression
Figure 6 RNA cell line category: Cell line enhanced (MCF7)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000093010-COMT
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Specifications
- Immunogen
- Human catechol-O-methyltransferase
- Host Species
- Human
- Derivation
- Human
- Type
- IgG
- Specificity
- Tested positive against native Human catechol-O-methyltransferase
- Species Reactivity
- Human
- Applications
- Used for immunoassaytechniques such as: Western blot; Neutralization; Functional Study
Product Property
- Purity
- >95% as determined by analysis by RP-HPLC
- Storage
- Short term: store at 4°C (over 6 months), long term: -20°C or -80°C.
Target
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "COMT"
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-231 | Recombinant Anti-human COMT Antibody | WB, IHC, FuncS | IgG |
| MOB-1690MZ | Recombinant Mouse Anti-Human COMT Antibody (clone 1G4-1A1) | ELISA, WB | Mouse antibody |
| MRO-0379-CN | Rabbit Anti-COMT Recombinant Antibody (clone JG39-48) | WB, IHC | Rabbit IgG |
| ZG-0063U | Rabbit Anti-COMT Recombinant Antibody (clone 8E1) | ELISA, WB, IHC | Rabbit IgG |
| VS3-WK535 | Rabbit Anti-COMT Recombinant Antibody (clone JM103-7) | WB, ELISA | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-231-F(E) | Recombinant Anti-human COMT Antibody Fab Fragment | RIA, IF, FuncS | Fab |
| MHH-231-F(E) | Recombinant Human Anti-human COMT Antibody Fab Fragment | ELISA, RIA, FuncS | Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-231-S(P) | Recombinant Anti-human COMT Antibody scFv Fragment | ELISA, WB, FuncS | scFv |
| MHH-231-S(P) | Recombinant Human Anti-human COMT Antibody scFv Fragment | ELISA, IF, FuncS | scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-0759 | Hi-Affi™ Rabbit Anti-COMT Recombinant Antibody (clone DS759AB) | WB, IHC | Rabbit IgG |
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