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    Recombinant Human Anti-human GDF11 Antibody (CAT#: MHH-390)

    Recombinant Human Antibody reacts with an antigen Human GDF11, expressed in HEK 293 cells. Expressed as the combination of a heavy chain (HC) containing VH from anti-GDF11 mAb and CH1-3 region of human IgG1 and a light chain (LC) encoding VL from anti-GDF11 mAb and CL of human kappa light chain. Exists as a disulfide linked dimer of the HC and LC hetero-dimer under non-reducing condition.

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    Custom Production

    We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.

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    We require custom production
    • Gene Expression
    • Datasheet
    • MSDS
    • COA
    Subcellular Location
    Figure 1 IF staining of human cell line U-2 OS
    Figure 1 IF staining of human cell line U-2 OS
    (Immunofluorescent staining of human cell line U-2 OS shows localization to vesicles.)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/60985/1118_F9_3_selected.jpg
    Figure 3 IF staining of human cell line CACO-2
    Figure 3 IF staining of human cell line CACO-2
    (Immunofluorescent staining of human cell line CACO-2 shows localization to vesicles.)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/60985/1261_D2_3_blue_red_green.jpg
    Normal Tissue
    Figure 2 IHC staining of human cerebral cortex
    Figure 2 IHC staining of human cerebral cortex
    (Immunohistochemical staining of human cerebral cortex shows strong cytoplasmic and nuclear positivity in a subset of glial cells.)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/69609/161896_B_7_5_selected.jpg
    Figure 4 Cerebral cortex
    Figure 4 Cerebral cortex
    (Glial cells
    Staining: High
    Intensity: Strong
    Quantity: 75%-25%
    Location: Cytoplasmic/membranous nuclear
    Neuropil
    Staining: Medium
    Intensity: Moderate
    Quantity: 75%-25%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/69609/161896_B_9_5.jpg
    Figure 5 Testis
    Figure 5 Testis
    (Leydig cells
    Staining: High
    Intensity: Strong
    Quantity:>75%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/69609/161896_A_4_6.jpg
    RNA Expression
    Figure 6 RNA cell line category: Cell line enhanced (HMC-1)
    Figure 6 RNA cell line category: Cell line enhanced (HMC-1)
    (Cell lines ordered by descending RNA expression order.)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000135414-GDF11

    Specifications

    • Immunogen
    • Human growth differentiation factor 11
    • Host Species
    • Human
    • Derivation
    • Human
    • Type
    • IgG
    • Specificity
    • Tested positive against native Human growth differentiation factor 11
    • Species Reactivity
    • Human
    • Applications
    • Products can be used for: Enzyme-linked Immunosorbent Assay; Western blot; Flow Cytometry; Functional Study

    Product Property

    • Purity
    • >95%, by SDS-PAGE with Coomassie Brilliant Blue staining
    • Storage
    • 4°C. For long term storage, aliquot and store at -20°C. Repeated thawing and freezing must be avoided.

    Target

    • Alternative Names
    • GDF11; growth differentiation factor 11; BMP11; BMP-11; growth/differentiation factor 11; GDF-11; bone morphogenetic protein 11

    Product Notes

    This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

    • Increased sensitivity
    • Confirmed specificity
    • High repeatability
    • Excellent batch-to-batch consistency
    • Sustainable supply
    • Animal-free production

    See more details about Hi-Affi™ recombinant antibody benefits.

    Downloads

    Download resources about recombinant antibody development and antibody engineering to boost your research.

    See other products for "GDF11"

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    CAT Product Name Application Type
    MOB-390 Recombinant Anti-human GDF11 Antibody ELISA, WB, IP, FuncS IgG
    MOB-0265CT Recombinant Mouse anti-Human GDF11 Monoclonal antibody (EML1029) IHC-P
    MRO-1696-CN Rabbit Anti-GDF11 Polyclonal Antibody (MRO-1696-CN) IF, IHC, FC Rabbit IgG
    VS3-FY2115 Rabbit Anti-GDF11 Recombinant Antibody (clone R41-2N-8) WB, IHC-P, IF Rabbit IgG

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