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    Recombinant Human Anti-human GDF11 Antibody (CAT#: MHH-390)

    Recombinant Human Antibody reacts with an antigen Human GDF11, expressed in HEK 293 cells. Expressed as the combination of a heavy chain (HC) containing VH from anti-GDF11 mAb and CH1-3 region of human IgG1 and a light chain (LC) encoding VL from anti-GDF11 mAb and CL of human kappa light chain. Exists as a disulfide linked dimer of the HC and LC hetero-dimer under non-reducing condition.

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    Custom Production

    We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.

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    We require custom production
    • Gene Expression
    • Datasheet
    • MSDS
    • COA
    Subcellular Location
    Figure 1 IF staining of human cell line U-2 OS
    Figure 1 IF staining of human cell line U-2 OS
    (Immunofluorescent staining of human cell line U-2 OS shows localization to vesicles.)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/60985/1118_F9_3_selected.jpg
    Figure 3 IF staining of human cell line CACO-2
    Figure 3 IF staining of human cell line CACO-2
    (Immunofluorescent staining of human cell line CACO-2 shows localization to vesicles.)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/60985/1261_D2_3_blue_red_green.jpg
    Normal Tissue
    Figure 2 IHC staining of human cerebral cortex
    Figure 2 IHC staining of human cerebral cortex
    (Immunohistochemical staining of human cerebral cortex shows strong cytoplasmic and nuclear positivity in a subset of glial cells.)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/69609/161896_B_7_5_selected.jpg
    Figure 4 Cerebral cortex
    Figure 4 Cerebral cortex
    (Glial cells
    Staining: High
    Intensity: Strong
    Quantity: 75%-25%
    Location: Cytoplasmic/membranous nuclear
    Neuropil
    Staining: Medium
    Intensity: Moderate
    Quantity: 75%-25%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/69609/161896_B_9_5.jpg
    Figure 5 Testis
    Figure 5 Testis
    (Leydig cells
    Staining: High
    Intensity: Strong
    Quantity:>75%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/69609/161896_A_4_6.jpg
    RNA Expression
    Figure 6 RNA cell line category: Cell line enhanced (HMC-1)
    Figure 6 RNA cell line category: Cell line enhanced (HMC-1)
    (Cell lines ordered by descending RNA expression order.)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000135414-GDF11

    Specifications

    • Immunogen
    • Human growth differentiation factor 11
    • Host Species
    • Human
    • Derivation
    • Human
    • Type
    • IgG
    • Specificity
    • Tested positive against native Human growth differentiation factor 11
    • Species Reactivity
    • Human
    • Applications
    • Products can be used for: Enzyme-linked Immunosorbent Assay; Western blot; Flow Cytometry; Functional Study

    Product Property

    • Purity
    • >95%, by SDS-PAGE with Coomassie Brilliant Blue staining
    • Storage
    • 4°C. For long term storage, aliquot and store at -20°C. Repeated thawing and freezing must be avoided.

    Target

    • Alternative Names
    • GDF11; growth differentiation factor 11; BMP11; BMP-11; growth/differentiation factor 11; GDF-11; bone morphogenetic protein 11

    Product Notes

    This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

    • Increased sensitivity
    • Confirmed specificity
    • High repeatability
    • Excellent batch-to-batch consistency
    • Sustainable supply
    • Animal-free production

    See more details about Hi-Affi™ recombinant antibody benefits.

    Downloads

    Download resources about recombinant antibody development and antibody engineering to boost your research.

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    CAT Product Name Application Type
    MOB-390 Recombinant Anti-human GDF11 Antibody ELISA, WB, IP, FuncS IgG
    MOB-0265CT Recombinant Mouse anti-Human GDF11 Monoclonal antibody (EML1029) IHC-P
    MRO-1696-CN Rabbit Anti-GDF11 Polyclonal Antibody (MRO-1696-CN) IF, IHC, FC Rabbit IgG
    VS3-FY2115 Rabbit Anti-GDF11 Recombinant Antibody (clone R41-2N-8) WB, IHC-P, IF Rabbit IgG

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    For Research Use Only. Not For Clinical Use.

    For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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