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    Recombinant Human Anti-human PAPPA Antibody (CAT#: MHH-748)

    Recombinant Human Antibody specifically reacts with Human PAPPA, expressed in HEK 293 cells. Expressed as the combination of a heavy chain (HC) containing VH from anti-PAPPA mAb and CH1-3 region of human IgG1 and a light chain (LC) encoding VL from anti-PAPPA mAb and CL of human kappa light chain. Exists as a disulfide linked dimer of the HC and LC hetero-dimer under non-reducing condition.

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    Custom Production

    We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.

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    We require custom production
    • Gene Expression
    • Datasheet
    • MSDS
    • COA
    Normal Tissue
    Figure 1 IHC staining of human placenta
    Figure 1 IHC staining of human placenta
    (High expression. RNA expression: 72.3 nTPM)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/1667/ihc_selected.jpg
    Figure 2 IHC staining of human prostate
    Figure 2 IHC staining of human prostate
    (Low expression. RNA expression: 1.1 nTPM)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/1667/7481_A_2_5_val_selected.jpg
    Figure 3 Cerebral cortex
    Figure 3 Cerebral cortex
    (Neuronal cells
    Staining: Medium
    Intensity: Moderate
    Quantity:>75%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/1667/7481_B_7_5.jpg
    Figure 4 Colon
    Figure 4 Colon
    (Glandular cells
    Staining: Not detected
    Intensity: Weak
    Quantity: <25%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/1667/7481_A_9_3.jpg
    Figure 5 Liver
    Figure 5 Liver
    (Cholangiocytes
    Staining: Medium
    Intensity: Moderate
    Quantity:>75%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/1667/7481_A_9_4.jpg
    Figure 6 Kidney
    Figure 6 Kidney
    (Cells in tubules
    Staining: High
    Intensity: Strong
    Quantity:>75%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/1667/7481_A_9_5.jpg
    Figure 7 Testis
    Figure 7 Testis
    (Cells in seminiferous ducts
    Staining: Not detected
    Intensity: Weak
    Quantity: <25%
    Location: Cytoplasmic/membranous
    Leydig cells
    Staining: Not detected
    Intensity: Weak
    Quantity: <25%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/1667/7481_A_4_6.jpg
    Figure 8 Lymph node
    Figure 8 Lymph node
    (Non-germinal center cells
    Staining: Medium
    Intensity: Moderate
    Quantity: 75%-25%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/1667/7481_A_8_8.jpg
    RNA Expression
    Figure 9 RNA cell line category: Cell line enhanced (ASC diff, ASC TERT1, HSkMC, U-138 MG)
    Figure 9 RNA cell line category: Cell line enhanced (ASC diff, ASC TERT1, HSkMC, U-138 MG)
    (Cell lines ordered by descending RNA expression order.)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000182752-PAPPA

    Specifications

    • Immunogen
    • Human pregnancy-associated plasma protein A, pappalysin 1
    • Host Species
    • Human
    • Derivation
    • Human
    • Type
    • IgG
    • Specificity
    • Tested positive against native Human pregnancy-associated plasma protein A, pappalysin 1
    • Species Reactivity
    • Human
    • Applications
    • Used for immunoassaytechniques such as: Immunoprecipitation; Immunofluorescence; Functional Study

    Product Property

    • Purity
    • >90% assessed by SDS-PAGE
    • Storage
    • Store it under sterile conditions at -20°C upon receiving. Recommend to pack the protein into smaller quantities for optimal storage.

    Target

    • Alternative Names
    • PAPPA; pregnancy-associated plasma protein A, pappalysin 1; PAPA; DIPLA1; PAPP-A; PAPPA1; ASBABP2; IGFBP-4ase; pappalysin-1; IGF-dependent IGFBP-4 protease; aspecific BCL2 ARE-binding protein 2; pregnacy-associated plasma protein A; differentially placent

    Product Notes

    This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

    • Increased sensitivity
    • Confirmed specificity
    • High repeatability
    • Excellent batch-to-batch consistency
    • Sustainable supply
    • Animal-free production

    See more details about Hi-Affi™ recombinant antibody benefits.

    Downloads

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    See other products for "PAPPA"

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    Please select product type
    IgG Antibodies Fab Antibodies ScFv Antibodies Rabbit Monoclonal Antibodies IHC Kits & Antibodies
    CAT Product Name Application Type
    MOB-748 Recombinant Anti-human PAPPA Antibody ELISA, WB, FuncS IgG
    MOB-1532CT Recombinant Mouse anti-Human PAPPA Monoclonal antibody (005-00) ELISA, IHC-Fr, IHC-P, WB
    HPAB-1890-FY Human Anti-PAPPA Recombinant Antibody (clone ABa01) Inhib Human IgG
    HPAB-1891-FY Human Anti-PAPPA Recombinant Antibody (clone ABa02) Inhib Human IgG
    HPAB-1892-FY Human Anti-PAPPA Recombinant Antibody (clone ABa03) Inhib Human IgG

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