Scorpion toxins scaffold protein anti-Cu2+ ions

CAT#: SSX-L183

The Scorpion toxin that bound Cu2+ ions was isolated from the library using Phage display techonology. After affinity maturation, Scorpion toxins variants were identified having affinities (KD=42 nM) for Cu2+ ions as determined by biosensor technology. It's potential to be used in diagnostic, research and therapeutic applications.

Specifications

  • Scaffold Name
  • Scorpion toxins
  • Origin
  • Scorpion toxins
  • Core Structure
  • Triple-stranded β-sheet, short α-helix
  • Variable Regions
  • Grafting of functional sites onto b-sheet
  • Target
  • Cu2+ ions
  • Expression Host
  • E. coli
  • Affinity Constant
  • 42 nM
  • Applications
  • ELISA; IHC; Microscopy; FC; WB; FuncS

Target

  • Alternative Names
  • Scorpion toxins; Scorpion toxins; Cu2+; Cu; Cu2+ ions
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